Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study (the ECHO-COVID study).

Aged COVID-19 Echocardiography Female Heart Failure Humans Hypertension, Pulmonary Intensive Care Units Male Pulmonary Embolism Retrospective Studies Ventricular Dysfunction, Left Ventricular Dysfunction, Right / diagnostic imaging

COVID-19 Cardiac function Echocardiography Intensive care unit

Journal

Intensive care medicine

ISSN: 1432-1238

Titre abrégé: Intensive Care Med

Pays: United States

ID NLM: 7704851

Informations de publication

Date de publication:
06 2022

Historique:

received: 19 01 2022

accepted: 16 03 2022

pubmed: 22 4 2022

medline: 22 6 2022

entrez: 21 4 2022

Statut: ppublish

Résumé

Severely ill patients affected by coronavirus disease 2019 (COVID-19) develop circulatory failure. We aimed to report patterns of left and right ventricular dysfunction in the first echocardiography following admission to intensive care unit (ICU). Retrospective, descriptive study that collected echocardiographic and clinical information from severely ill COVID-19 patients admitted to 14 ICUs in 8 countries. Patients admitted to ICU who received at least one echocardiography between 1st February 2020 and 30th June 2021 were included. Clinical and echocardiographic data were uploaded using a secured web-based electronic database (REDCap). Six hundred and seventy-seven patients were included and the first echo was performed 2 [1, 4] days after ICU admission. The median age was 65 [56, 73] years, and 71% were male. Left ventricle (LV) and/or right ventricle (RV) systolic dysfunction were found in 234 (34.5%) patients. 149 (22%) patients had LV systolic dysfunction (with or without RV dysfunction) without LV dilatation and no elevation in filling pressure. 152 (22.5%) had RV systolic dysfunction. In 517 patients with information on both paradoxical septal motion and quantitative RV size, 90 (17.4%) had acute cor pulmonale (ACP). ACP was associated with mechanical ventilation (OR > 4), pulmonary embolism (OR > 5) and increased PaCO Almost one-third of this cohort of critically ill COVID-19 patients exhibited abnormal LV and/or RV systolic function in their first echocardiography assessment. While LV systolic dysfunction appears similar to septic cardiomyopathy, RV systolic dysfunction was related to pressure overload due to positive pressure ventilation, hypercapnia and pulmonary embolism. ACP and age seemed to be associated with mortality in this cohort.

Identifiants

DOI: 10.1007/s00134-022-06685-2 PMID: 35445822 PMC: PMC9022062

pubmed: 35445822

doi: 10.1007/s00134-022-06685-2

pii: 10.1007/s00134-022-06685-2

pmc: PMC9022062

doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

Pagination

667-678

Investigateurs

Anne-Marie Welsh (AM)

H Didriksson (H)

Yoann Zerbib (Y)

Clément Brault (C)

Laetitia Bodénes (L)

Nicolas Ferrière (N)

S Clavier (S)

I Ma (I)

Luigi La Via (L)

Veronica Dezio (V)

J B Rius (JB)

J R Palomares (JR)

Fernando Piscioneri (F)

S Giglioli (S)

S Banauch-Mayer (S)

Bruno François (B)

Anne-Laure Fedoux (AL)

Thomas Daix (T)

Commentaires et corrections

Type : CommentIn

Informations de copyright

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