Five nanometer size highly positive silver nanoparticles are bactericidal targeting cell wall and adherent fimbriae expression.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
25 04 2022
25 04 2022
Historique:
received:
19
10
2021
accepted:
08
04
2022
entrez:
26
4
2022
pubmed:
27
4
2022
medline:
28
4
2022
Statut:
epublish
Résumé
To tackle growing antibiotic resistance (AR) and hospital-acquired infections (HAIs), novel antimicrobials are warranted that are effective against HAIs and safer for human use. We hypothesize that small 5 nm size positively charged nanoparticles could specifically target bacterial cell wall and adherent fimbriae expression, serving as the next generation antibacterial agent. Herein we show highly positively charged, 5 nm amino-functionalized silver nanoparticles (NH
Identifiants
pubmed: 35468937
doi: 10.1038/s41598-022-10778-9
pii: 10.1038/s41598-022-10778-9
pmc: PMC9039075
doi:
Substances chimiques
Anti-Bacterial Agents
0
Ions
0
Citric Acid
2968PHW8QP
Silver
3M4G523W1G
Dihydrotachysterol
R5LM3H112R
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6729Informations de copyright
© 2022. The Author(s).
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