Synthesis and cholinesterase inhibitory activity study of Amaryllidaceae alkaloid analogues with

Acetylcholinesterase / metabolism Alkaloids / chemistry Amaryllidaceae / chemistry Amaryllidaceae Alkaloids / chemistry Butyrylcholinesterase / metabolism Cholinesterase Inhibitors / chemistry Humans Molecular Docking Simulation Nitrogen Structure-Activity Relationship

Journal

Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995

Informations de publication

Date de publication:
18 05 2022
Historique:
pubmed: 27 4 2022
medline: 20 5 2022
entrez: 26 4 2022
Statut: epublish

Résumé

Polycyclic compounds with

Identifiants

DOI: 10.1039/d2ob00553k PMID: 35471452
pubmed: 35471452
doi: 10.1039/d2ob00553k
doi:

Substances chimiques

Alkaloids 0
Amaryllidaceae Alkaloids 0
Cholinesterase Inhibitors 0
Acetylcholinesterase EC 3.1.1.7
Butyrylcholinesterase EC 3.1.1.8
Nitrogen N762921K75

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3960-3966

Auteurs

Petr Jansa (P)

Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 00 Praha 2, Czech Republic. eliska.matousova@natur.cuni.cz.

Ivan Barvík (I)

Faculty of Mathematics and Physics, Institute of Physics, Charles University, Ke Karlovu 2026/5, 121 16 Praha 2, Czech Republic.
ORCID: 0000-0002-0802-1346

Daniela Hulcová (D)

Department of Pharmacognosy, Faculty of Pharmacy, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic.
ORCID: 0000-0003-2414-3551

Eliška Matoušová (E)

Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 00 Praha 2, Czech Republic. eliska.matousova@natur.cuni.cz.
ORCID: 0000-0002-3248-5263

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Carboxylic ester hydrolases › Cholinesterases › Acetylcholinesterase › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Composés hétérocycliques › Alcaloïdes › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Lilianae › Asparagales › Amaryllidaceae › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Composés hétérocycliques › Alcaloïdes › Alcaloïdes des Amaryllidaceae › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Carboxylic ester hydrolases › Cholinesterases › Butyrylcholine esterase › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents cholinergiques › Anticholinestérasiques › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Azote › Synthesis and cholinesterase inhibitory...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Synthesis and cholinesterase inhibitory...