Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome.
Lynch syndrome
MLH3 gene
colorectal cancer genes
custom panel
in silico analysis
microsatellite instability‑high status
mismatch repair genes
next‑generation sequencing
rare variants
uncertain variants
Journal
International journal of molecular medicine
ISSN: 1791-244X
Titre abrégé: Int J Mol Med
Pays: Greece
ID NLM: 9810955
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
14
12
2021
accepted:
09
03
2022
entrez:
27
4
2022
pubmed:
28
4
2022
medline:
29
4
2022
Statut:
ppublish
Résumé
The molecular characterization of patients with Lynch syndrome (LS) involves germline testing to detect a deleterious mutation in one of the genes of the mismatch repair (
Identifiants
pubmed: 35475445
doi: 10.3892/ijmm.2022.5137
pii: 81
pmc: PMC9083887
doi:
pii:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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