Topographical changes and bactericidal efficacy of antimicrobial photodynamic therapy on titanium implant surface.

Anti-Bacterial Agents Anti-Infective Agents Biofilms Photochemotherapy / methods Photosensitizing Agents / pharmacology Porphyromonas gingivalis Titanium / pharmacology
Antimicrobial photodynamic therapy Chlorhexidine and hydrogen peroxide Disinfectants Laser therapy Surface modification Titanium

Journal

Photodiagnosis and photodynamic therapy
ISSN: 1873-1597
Titre abrégé: Photodiagnosis Photodyn Ther
Pays: Netherlands
ID NLM: 101226123

Informations de publication

Date de publication:
Sep 2022
Historique:
received: 04 04 2022
revised: 20 04 2022
accepted: 22 04 2022
pubmed: 28 4 2022
medline: 9 9 2022
entrez: 27 4 2022
Statut: ppublish

Résumé

reExtensive rsearch has been done on various disinfection modalities used to achieve an aseptic implant surface. However, the bacterial efficacy and the topographical alterations resulting from the use of these techniques have never been compared. This study aimed to evaluate and compare the disinfection efficacy and surface changes on a bacteria contaminated titanium block following application of various disinfectants. Ultrasonically cleaned titanium blocks were contaminated with Porphyromonas gingivalis and Tannerella forsythia. The infected titanium implants were randomly divided into four experimental groups and decontaminated using antimicrobial photodynamic therapy (aPDT), laser therapy, chlorhexidine and hydrogen peroxide. Bacterial viability and surface changes following decontamination were analyzed. Bacterial viability decreased in all the groups, with aPDT having the highest reduction. Surface roughness remained unchanged whereas the contact angle lessened in the aPDT group. aPDT could possibly be a suitable alternative to other disinfection regimen to treat periimplantitis.

Sections du résumé

BACKGROUND BACKGROUND
reExtensive rsearch has been done on various disinfection modalities used to achieve an aseptic implant surface. However, the bacterial efficacy and the topographical alterations resulting from the use of these techniques have never been compared.
OBJECTIVE OBJECTIVE
This study aimed to evaluate and compare the disinfection efficacy and surface changes on a bacteria contaminated titanium block following application of various disinfectants.
METHOD METHODS
Ultrasonically cleaned titanium blocks were contaminated with Porphyromonas gingivalis and Tannerella forsythia. The infected titanium implants were randomly divided into four experimental groups and decontaminated using antimicrobial photodynamic therapy (aPDT), laser therapy, chlorhexidine and hydrogen peroxide. Bacterial viability and surface changes following decontamination were analyzed.
RESULT RESULTS
Bacterial viability decreased in all the groups, with aPDT having the highest reduction. Surface roughness remained unchanged whereas the contact angle lessened in the aPDT group.
CONCLUSION CONCLUSIONS
aPDT could possibly be a suitable alternative to other disinfection regimen to treat periimplantitis.

Identifiants

DOI: 10.1016/j.pdpdt.2022.102882 PMID: 35477046
pubmed: 35477046
pii: S1572-1000(22)00168-5
doi: 10.1016/j.pdpdt.2022.102882
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Anti-Infective Agents 0
Photosensitizing Agents 0
Titanium D1JT611TNE

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

102882

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Sukumaran Anil (S)

Department of Dentistry-Oral Health Institute, Hamad Medical Corporation, Doha, Qatar; College of Dental Medicine, Qatar University, Doha, Qatar. Electronic address: drsanil@gmail.com.

Omar Alageel (O)

Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.

Omar Alsadon (O)

Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.

Samer M Alaqeel (SM)

Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.

Majed M Alsarani (MM)

Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.

Mohamed Hashem (M)

Dental Health Department, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.

Hassan Fouad (H)

Applied Medical Science Department, CC, King Saud University, P.O Box 10219, Riyadh, 11433, Saudi Arabia.

Mohammad Javaid (M)

School of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Topographical changes and bactericidal...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Topographical changes and bactericidal...
questionsmedicales.fr › Phénomènes microbiologiques › Biofilms › Topographical changes and bactericidal...
questionsmedicales.fr › Thérapeutique › Photothérapie › Photothérapie dynamique › Topographical changes and bactericidal...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Radiosensibilisants › Photosensibilisants › Topographical changes and bactericidal...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Bactéries anaérobies à Gram négatif › Bâtonnets à Gram négatif anaérobies droits, incurvés et spiralés › Bacteroidaceae › Porphyromonas › Porphyromonas gingivalis › Topographical changes and bactericidal...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux légers › Titane › Topographical changes and bactericidal...