The anterior thalamic nuclei: core components of a tripartite episodic memory system.
Journal
Nature reviews. Neuroscience
ISSN: 1471-0048
Titre abrégé: Nat Rev Neurosci
Pays: England
ID NLM: 100962781
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
accepted:
25
03
2022
pubmed:
29
4
2022
medline:
23
7
2022
entrez:
28
4
2022
Statut:
ppublish
Résumé
Standard models of episodic memory focus on hippocampal-parahippocampal interactions, with the neocortex supplying sensory information and providing a final repository of mnemonic representations. However, recent advances have shown that other regions make distinct and equally critical contributions to memory. In particular, there is growing evidence that the anterior thalamic nuclei have a number of key cognitive functions that support episodic memory. In this article, we describe these findings and argue for a core, tripartite memory system, comprising a 'temporal lobe' stream (centred on the hippocampus) and a 'medial diencephalic' stream (centred on the anterior thalamic nuclei) that together act on shared cortical areas. We demonstrate how these distributed brain regions form complementary and necessary partnerships in episodic memory formation.
Identifiants
pubmed: 35478245
doi: 10.1038/s41583-022-00591-8
pii: 10.1038/s41583-022-00591-8
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
505-516Subventions
Organisme : Wellcome Trust
ID : 103722/Z14/Z
Pays : United Kingdom
Informations de copyright
© 2022. Springer Nature Limited.
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