Povidone-iodine irrigation reduces infection after total hip and knee arthroplasty.
Infection
Periprosthetic infection
Povidone-iodine
Total hip arthroplasty
Total knee arthroplasty
Journal
Archives of orthopaedic and trauma surgery
ISSN: 1434-3916
Titre abrégé: Arch Orthop Trauma Surg
Pays: Germany
ID NLM: 9011043
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
18
06
2021
accepted:
15
04
2022
pubmed:
1
5
2022
medline:
24
3
2023
entrez:
30
4
2022
Statut:
ppublish
Résumé
One of the most important challenges faced by orthopedic surgeons is periprosthetic joint infection (PJI). PJI is a common cause for total joint arthroplasty failure with an incidence of 0.3-1.9%. PJI can be devastating for the patient and extremely costly for the healthcare system. There is concern that a major cause of PJI is intra-operative colonization and recent studies have shown a decrease in PJI with the use of dilute povidone-iodine (Betadine Retrospective chart review performed at our hospital looking at PJI amongst patients who underwent primary total hip arthroplasty (THA) or total knee arthroplasty (TKA) between 2013 and 2017 comparing different irrigation methods (n = 3232). The study group (n = 1207) underwent irrigation prior to wound closure with dilute Betadine for 3 min and the control group (n = 1511) underwent irrigation using normal saline (NS). Using a logistic regression model where the following variables were adjusted for; ASA, age, sex, foley insertion, surgical duration and diabetes mellitus status a statistical significant reduction was seen in any infection (OR 0.45 [0.22; 0.89], p value < 0.05) and SSI (OR 0.30 [0.13; 0.70], p value 0.01) with the Betadine group. No significant reduction was seen with deep infections with the Betadine group compared to the NS group. PJI is a devastating complication following total joint arthroplasty and we found Betadine compared to NS irrigation provides an inexpensive and simple method to lower any PJI and more specifically SSI in THA and TKA. III.
Identifiants
pubmed: 35488919
doi: 10.1007/s00402-022-04451-z
pii: 10.1007/s00402-022-04451-z
doi:
Substances chimiques
Povidone-Iodine
85H0HZU99M
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2175-2180Informations de copyright
© 2022. Crown.
Références
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