Neonatal morbidities and postnatal growth failure in very low birth weight, very preterm infants.


Journal

Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
Titre abrégé: Acta Paediatr
Pays: Norway
ID NLM: 9205968

Informations de publication

Date de publication:
08 2022
Historique:
revised: 17 04 2022
received: 16 02 2022
accepted: 27 04 2022
pubmed: 2 5 2022
medline: 14 7 2022
entrez: 1 5 2022
Statut: ppublish

Résumé

To assess postnatal growth in infants with and without major neonatal morbidities. This study is based on analysis of data collected by the Israel Neonatal Network on VLBW infants (≤1500 g) born in Israel from 2009 to 2018. Postnatal growth was assessed in two 5 years epochs: 2009-2013 (n = 4583) and 2014-2018 (n = 4558). Outcome was considered as severe, mild and no postnatal growth failure (PNGF). Morbidities included respiratory distress syndrome, bronchopulmonary dysplasia, necrotising enterocolitis, patent ductus arteriosus and grades 3-4 intraventricular haemorrhage. Multinomial logistic regression analyses with the generalised estimating equation approach were applied. The study population composed 9141 infants. Of them, 2089 had at least one major morbidity and 7052 infants had none. In infants with no morbidities, 2.1% had severe PNGF, 23.7% mild PNGF and 74.2% had no PNGF, as compared to 13.6%, 43.9% and 42.5%, respectively, in infants with any major neonatal morbidity (p < 0.0001). Despite enormous advances in neonatal care, postnatal growth remains a challenge in VLBW infants, particularly in infants with major neonatal morbidities. Along with efforts to decrease morbidity, a more personalised plan and follow-up may be required in infants with major morbidities, given their high risk for diminished growth and potentially, adverse neurodevelopmental outcomes.

Identifiants

pubmed: 35490375
doi: 10.1111/apa.16380
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1536-1545

Informations de copyright

© 2022 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Références

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Auteurs

Noa Ofek Shlomai (N)

Department of Neonatology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Brian Reichman (B)

Women and Children's Health Research Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Inna Zaslavsky-Paltiel (I)

Women and Children's Health Research Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel.

Liat Lerner-Geva (L)

Women and Children's Health Research Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Smadar Eventov-Friedman (S)

Department of Neonatology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

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