Molecular Determinants of Human T-cell Leukemia Virus Type 1 Gag Targeting to the Plasma Membrane for Assembly.

Arginine / metabolism Cell Membrane / metabolism Gene Products, gag / genetics Human T-lymphotropic virus 1 / genetics Humans Lysine / metabolism Phosphatidylinositol 4,5-Diphosphate / metabolism Phosphatidylserines / chemistry Protein Binding Virus Assembly
Gag polyprotein human T-cell leukemia virus type 1 (HTLV-1) human immunodeficiency virus type 1 (HIV-1) matrix (MA) protein plasma membrane (PM)

Journal

Journal of molecular biology
ISSN: 1089-8638
Titre abrégé: J Mol Biol
Pays: Netherlands
ID NLM: 2985088R

Informations de publication

Date de publication:
30 06 2022
Historique:
received: 28 02 2022
revised: 20 04 2022
accepted: 23 04 2022
pubmed: 2 5 2022
medline: 9 6 2022
entrez: 1 5 2022
Statut: ppublish

Résumé

Assembly of human T-cell leukemia virus type 1 (HTLV-1) particles is initiated by the trafficking of virally encoded Gag polyproteins to the inner leaflet of the plasma membrane (PM). Gag-PM interactions are mediated by the matrix (MA) domain, which contains a myristoyl group (myr) and a basic patch formed by lysine and arginine residues. For many retroviruses, Gag-PM interactions are mediated by phosphatidylinositol 4,5-bisphosphate [PI(4,5)P

Identifiants

DOI: 10.1016/j.jmb.2022.167609 PMID: 35490898 PMC: PMC10557380
pubmed: 35490898
pii: S0022-2836(22)00189-9
doi: 10.1016/j.jmb.2022.167609
pmc: PMC10557380
mid: NIHMS1934950
pii:
doi:

Substances chimiques

Gene Products, gag 0
Phosphatidylinositol 4,5-Diphosphate 0
Phosphatidylserines 0
Arginine 94ZLA3W45F
Lysine K3Z4F929H6

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

167609

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI150901
Pays : United States
Organisme : NIAID NIH HHS
ID : R37 AI150901
Pays : United States

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

J Virol. 2013 Mar;87(6):3609-15
pubmed: 23325682
J Biomol NMR. 1994 Sep;4(5):603-14
pubmed: 22911360
J Virol. 2007 Sep;81(17):8977-88
pubmed: 17596311
J Virol. 2011 Apr;85(8):3802-10
pubmed: 21289126
J Mol Biol. 2009 Jul 24;390(4):775-90
pubmed: 19481095
Front Microbiol. 2014 Jan 21;4:423
pubmed: 24478762
Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11364-9
pubmed: 16840558
J Virol. 2019 Nov 13;93(23):
pubmed: 31511376
J Virol. 2002 Jan;76(2):905-11
pubmed: 11752179
J Virol. 2009 Jun;83(11):5375-87
pubmed: 19297499
J Mol Graph. 1996 Feb;14(1):33-8, 27-8
pubmed: 8744570
Biochemistry. 2006 Apr 4;45(13):4077-83
pubmed: 16566581
Traffic. 2011 Apr;12(4):438-51
pubmed: 21176037
J Comput Chem. 2010 Mar;31(4):671-90
pubmed: 19575467
PLoS Pathog. 2016 Oct 24;12(10):e1005916
pubmed: 27776189
Bioinformatics. 2013 Apr 1;29(7):845-54
pubmed: 23407358
J Mol Biol. 2008 Oct 3;382(2):434-47
pubmed: 18657545
Front Microbiol. 2012 Nov 15;3:388
pubmed: 23162541
Annu Rev Immunol. 2018 Apr 26;36:43-71
pubmed: 29144838
J Cell Biol. 1988 Nov;107(5):1707-15
pubmed: 2846585
J Biol Chem. 2018 Dec 7;293(49):18841-18853
pubmed: 30309982
Front Microbiol. 2015 Mar 20;6:232
pubmed: 25852680
Proteins. 2013 Oct;81(10):1776-91
pubmed: 23760740
Biophys J. 2011 Mar 16;100(6):1587-95
pubmed: 21402042
J Virol. 1999 May;73(5):4136-44
pubmed: 10196310
Proc Natl Acad Sci U S A. 1990 Jan;87(2):523-7
pubmed: 2405382
J Virol. 1997 Jan;71(1):259-66
pubmed: 8985345
Lancet. 1985 Aug 24;2(8452):407-10
pubmed: 2863442
Biophys J. 2010 Aug 4;99(3):979-88
pubmed: 20682277
Int J Mol Sci. 2020 Nov 06;21(21):
pubmed: 33172190
J Biomol NMR. 1995 Nov;6(3):277-93
pubmed: 8520220
J Mol Biol. 2012 Oct 26;423(3):427-38
pubmed: 22863803
Curr Opin Struct Biol. 2008 Apr;18(2):203-17
pubmed: 18406133
J Comput Chem. 2008 Aug;29(11):1859-65
pubmed: 18351591
J Virol. 2007 Jul;81(14):7476-90
pubmed: 17507489
J Mol Biol. 2016 Feb 22;428(4):720-725
pubmed: 26410586
J Biol Chem. 2019 Dec 6;294(49):18600-18612
pubmed: 31640987
Virus Res. 2014 Nov 26;193:108-15
pubmed: 24998886
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3525-30
pubmed: 23401539
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7415-9
pubmed: 6261256
Viruses. 2015 Apr 30;7(5):2210-29
pubmed: 25941825
Front Microbiol. 2012 Feb 17;3:55
pubmed: 22363329
PLoS Pathog. 2007 Mar;3(3):e36
pubmed: 17381240
Ann Neurol. 1987 Feb;21(2):117-22
pubmed: 2881513
J Mol Biol. 2007 Feb 16;366(2):574-85
pubmed: 17188710
mBio. 2014 Dec 09;5(6):e02202
pubmed: 25491356
J Virol. 2008 Mar;82(5):2405-17
pubmed: 18094158
Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14889-94
pubmed: 15465916
J Virol. 1996 Dec;70(12):8540-8
pubmed: 8970978
Biophys Chem. 2006 Jan 1;119(1):23-32
pubmed: 16183191
PLoS Biol. 2006 Dec;4(12):e435
pubmed: 17147474
J Mol Biol. 2016 Apr 24;428(8):1637-55
pubmed: 26992353
J Mol Biol. 2014 Apr 3;426(7):1611-24
pubmed: 24316368
J Virol. 2004 Feb;78(3):1503-12
pubmed: 14722305
J Virol. 2000 Apr;74(7):3264-72
pubmed: 10708443
Biochemistry. 2010 Jun 29;49(25):5109-16
pubmed: 20496925
Gene. 1992 Oct 1;119(2):273-7
pubmed: 1398108
J Comput Chem. 2012 Dec 5;33(31):2451-68
pubmed: 22821581
J Biol Chem. 2018 Dec 7;293(49):18828-18840
pubmed: 30309983
J Virol. 2010 Jan;84(1):503-15
pubmed: 19828619
J Mol Biol. 2021 Sep 17;433(19):167161
pubmed: 34298060
Nat Rev Microbiol. 2015 Aug;13(8):484-96
pubmed: 26119571
J Virol. 1999 Mar;73(3):1860-7
pubmed: 9971764
Biophys J. 2020 Jan 21;118(2):281-293
pubmed: 31870539
J Virol. 1997 Sep;71(9):6582-92
pubmed: 9261380
PLoS Pathog. 2008 Mar 07;4(3):e1000015
pubmed: 18369466
J Am Chem Soc. 2003 Feb 19;125(7):1731-7
pubmed: 12580598
Proc Natl Acad Sci U S A. 1982 Mar;79(6):2031-5
pubmed: 6979048
J Virol. 2007 Sep;81(18):9769-77
pubmed: 17609263

Auteurs

Dominik Herrmann (D)

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, United States.

Heather M Hanson (HM)

Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455, United States.

Lynne W Zhou (LW)

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, United States.

Rayna Addabbo (R)

Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455, United States; School of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455, United States.

Nora A Willkomm (NA)

Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455, United States.

Isaac Angert (I)

Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455, United States; School of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455, United States.

Joachim D Mueller (JD)

Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455, United States; School of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455, United States.

Louis M Mansky (LM)

Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455, United States. Electronic address: mansky@umn.edu.

Jamil S Saad (JS)

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, United States. Electronic address: saad@uab.edu.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Arginine › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Protéines nucléocapside › Protéines du core viral › Produits du gène gag › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Deltaretrovirus › Virus T-lymphotrope de type 1 des primates › Virus T-lymphotrope humain de type 1 › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Lysine › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Lipides › Lipides membranaires › Phospholipides › Glycérophosphate › Acides phosphatidiques › Glycérophospholipides › Phosphatidyl inositols › Phosphates phosphatidylinositol › Phosphatidylinositol diphosphate-4,5 › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Lipides › Lipides membranaires › Phospholipides › Glycérophosphate › Acides phosphatidiques › Glycérophospholipides › Phosphatidylsérine › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Molecular Determinants of Human T-cell...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Réplication virale › Assemblage viral › Molecular Determinants of Human T-cell...