Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

ADAMTS Proteins / chemistry Animals Fibrillin-1 / genetics Fibrillin-2 / metabolism Fibrillins / metabolism Mice Microfibrils / metabolism Proteolysis
ADAMTS Protease developmental biology extracellular matrix fibrillin mouse proteolysis skeletal development

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
03 05 2022
Historique:
received: 10 06 2021
accepted: 13 04 2022
entrez: 3 5 2022
pubmed: 4 5 2022
medline: 6 5 2022
Statut: epublish

Résumé

The embryonic extracellular matrix (ECM) undergoes transition to mature ECM as development progresses, yet few mechanisms ensuring ECM proteostasis during this period are known. Fibrillin microfibrils are macromolecular ECM complexes serving structural and regulatory roles. In mice,

Identifiants

DOI: 10.7554/eLife.71142 PMID: 35503090 PMC: PMC9064305
pubmed: 35503090
doi: 10.7554/eLife.71142
pii: 71142
pmc: PMC9064305
doi:
pii:

Substances chimiques

Fibrillin-1 0
Fibrillin-2 0
Fibrillins 0
ADAMTS Proteins EC 3.4.24.-
ADAMTS10 protein, mouse EC 3.4.24.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAMS NIH HHS
ID : F32 AR063548
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL156987
Pays : United States
Organisme : NIDDK NIH HHS
ID : TL1 DK132770
Pays : United States
Organisme : CIHR
ID : PJT-162099
Pays : Canada

Informations de copyright

© 2022, Mead et al.

Déclaration de conflit d'intérêts

TM, DM, LW, SC, CG, EC, JM, DR, CL, CB, SA No competing interests declared

Références

Cell Rep. 2015 Jun 16;11(10):1519-28
pubmed: 26027930
J Biol Chem. 2019 Jun 21;294(25):9924-9936
pubmed: 31085586
J Biol Chem. 2005 May 27;280(21):20349-55
pubmed: 15788413
J Biol Chem. 2005 Aug 26;280(34):30526-37
pubmed: 15980072
Invest Ophthalmol Vis Sci. 2012 Jan 31;53(1):461-9
pubmed: 21989719
J Biol Chem. 2005 Feb 11;280(6):5013-21
pubmed: 15569675
Sci Rep. 2017 Feb 08;7:41871
pubmed: 28176809
Mol Biol Cell. 2009 Feb;20(3):846-58
pubmed: 19037100
J Biol Chem. 2002 Dec 27;277(52):50795-804
pubmed: 12399449
Matrix Biol. 2018 Oct;71-72:225-239
pubmed: 29885460
J Biol Chem. 2010 Jun 25;285(26):20242-51
pubmed: 20404337
Nature. 2015 May 28;521(7553):520-4
pubmed: 25807483
BMC Evol Biol. 2007 Apr 17;7:63
pubmed: 17439641
J Biol Chem. 2010 Feb 12;285(7):4870-82
pubmed: 19940141
Genesis. 2014 Jul;52(7):702-12
pubmed: 24753090
Matrix Biol. 2019 Jan;75-76:170-189
pubmed: 29133183
Essays Biochem. 2019 Sep 13;63(3):365-376
pubmed: 31395654
Methods Mol Biol. 2020;2043:173-178
pubmed: 31463911
Hum Mol Genet. 2018 Nov 1;27(21):3675-3687
pubmed: 30060141
J Biol Chem. 2011 Feb 18;286(7):5087-99
pubmed: 21135108
Matrix Biol. 2015 Sep;47:13-33
pubmed: 25963142
Matrix Biol. 2015 May-Jul;44-46:24-37
pubmed: 25770910
J Biol Chem. 2006 Mar 24;281(12):8016-23
pubmed: 16407178
Development. 2005 Mar;132(5):1057-67
pubmed: 15689378
Genome Biol. 2018 Jul 17;19(1):87
pubmed: 30012220
Am J Hum Genet. 2004 Nov;75(5):801-6
pubmed: 15368195
J Cell Biol. 2010 Sep 20;190(6):1107-21
pubmed: 20855508
Invest Ophthalmol Vis Sci. 2013 Dec 23;54(13):8337-44
pubmed: 24265020
Genomics. 2004 Mar;83(3):461-72
pubmed: 14962672
Matrix Biol. 2012 Sep-Oct;31(7-8):398-411
pubmed: 23010571
J Biol Chem. 2016 Jun 10;291(24):12732-12746
pubmed: 27059954
Int J Biochem Cell Biol. 2005 Sep;37(9):1838-45
pubmed: 15899586
FASEB J. 2016 May;30(5):1741-56
pubmed: 26740262
Matrix Biol. 2018 Oct;71-72:82-89
pubmed: 28782645
Nat Methods. 2012 Jun 28;9(7):676-82
pubmed: 22743772
J Med Genet. 2006 Oct;43(10):769-87
pubmed: 16571647
Stem Cells. 2015 Mar;33(3):762-73
pubmed: 25377511
Am J Hum Genet. 2009 Nov;85(5):558-68
pubmed: 19836009
Curr Opin Cell Biol. 2009 Oct;21(5):616-22
pubmed: 19525102
Curr Top Dev Biol. 2019;133:343-385
pubmed: 30902258
J Biol Chem. 2001 Oct 26;276(43):39661-6
pubmed: 11481325
Dev Cell. 2009 Nov;17(5):687-98
pubmed: 19922873
J Cell Biol. 1994 Mar;124(5):855-63
pubmed: 8120105
Semin Cell Dev Biol. 2017 Feb;62:16-33
pubmed: 27180955
J Mol Biol. 1999 Jan 22;285(3):1277-87
pubmed: 9887276
J Biol Chem. 2011 May 13;286(19):17156-67
pubmed: 21402694
Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):573-585
pubmed: 28125844
JCI Insight. 2018 Apr 5;3(7):
pubmed: 29618652
J Cell Biol. 2001 Jul 23;154(2):275-81
pubmed: 11470817
Nature. 2019 Apr;568(7751):193-197
pubmed: 30944477
Nat Commun. 2019 Feb 27;10(1):953
pubmed: 30814516
Matrix Biol. 2019 Nov;84:31-40
pubmed: 31669522
J Cell Sci. 2008 Aug 15;121(Pt 16):2696-704
pubmed: 18653538
J Biol Chem. 2006 Apr 14;281(15):10089-97
pubmed: 16492672
Proteomics. 2006 Jan;6(1):111-22
pubmed: 16302274
Nat Genet. 2008 Sep;40(9):1119-23
pubmed: 18677313
J Med Genet. 2003 Jan;40(1):34-6
pubmed: 12525539
Matrix Biol. 2011 Jan;30(1):43-52
pubmed: 20970500
Proc Natl Acad Sci U S A. 2008 May 6;105(18):6548-53
pubmed: 18448684
Development. 2010 Dec;137(23):4029-38
pubmed: 21041365
J Cell Biol. 1995 May;129(4):1165-76
pubmed: 7744963
Matrix Biol. 2007 Jan;26(1):2-11
pubmed: 17055232
Development. 2020 Aug 14;147(15):
pubmed: 32816903
Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3819-23
pubmed: 10097121
Nat Biotechnol. 2010 Mar;28(3):281-8
pubmed: 20208520
FASEB J. 2021 Mar;35(3):e21353
pubmed: 33629769
Am J Med Genet A. 2003 Dec 1;123A(2):204-7
pubmed: 14598350
Methods Mol Biol. 2020;2043:207-212
pubmed: 31463914
J Biol Chem. 2005 Jul 29;280(30):27970-80
pubmed: 15929982
Science. 1996 Aug 2;273(5275):613-22
pubmed: 8662546
Biomolecules. 2020 Apr 12;10(4):
pubmed: 32290605
Elife. 2022 May 03;11:
pubmed: 35503090
Sci Rep. 2020 Oct 7;10(1):16659
pubmed: 33028938
Matrix Biol. 2019 Apr;77:117-128
pubmed: 30201140
Semin Cell Dev Biol. 2019 May;89:109-117
pubmed: 30016650
PLoS One. 2010 Sep 17;5(9):
pubmed: 20862248
Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14420-5
pubmed: 19590010
JCI Insight. 2020 Jul 23;5(14):
pubmed: 32544089
Matrix Biol. 2015 Sep;47:34-43
pubmed: 25957949
J Biol Chem. 2008 May 16;283(20):13874-88
pubmed: 18339631
J Biol Chem. 2011 Nov 4;286(44):38602-38613
pubmed: 21880733
J Biol Chem. 2004 Dec 3;279(49):51208-17
pubmed: 15355968
Matrix Biol Plus. 2021 May 14;10:100064
pubmed: 34195596
Sci Rep. 2016 Oct 25;6:35956
pubmed: 27779234
Sci Rep. 2017 Mar 02;7:43714
pubmed: 28252045
J Bone Miner Res. 2000 Jan;15(1):68-81
pubmed: 10646116
J Biol Chem. 2003 Jan 24;278(4):2740-9
pubmed: 12429739
J Cell Biochem. 2004 Apr 15;91(6):1204-17
pubmed: 15048875
PLoS Genet. 2015 Jun 26;11(6):e1005340
pubmed: 26114882

Auteurs

Timothy J Mead (TJ)

Department of Biomedical Engineering and Musculoskeletal Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.
ORCID: 0000-0003-1891-3652

Daniel R Martin (DR)

Department of Biomedical Engineering and Musculoskeletal Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.

Lauren W Wang (LW)

Department of Biomedical Engineering and Musculoskeletal Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.

Stuart A Cain (SA)

Division of Cell-Matrix Biology and Regenerative Medicine, Wellcome Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

Cagri Gulec (C)

Department of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.

Elisabeth Cahill (E)

Department of Biomedical Engineering and Musculoskeletal Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.

Joseph Mauch (J)

Department of Biomedical Engineering and Musculoskeletal Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.

Dieter Reinhardt (D)

Faculty of Medicine and Health Sciences and Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Canada.

Cecilia Lo (C)

Department of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.

Clair Baldock (C)

Division of Cell-Matrix Biology and Regenerative Medicine, Wellcome Centre for Cell-Matrix Research, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom.

Suneel S Apte (SS)

Department of Biomedical Engineering and Musculoskeletal Research Center, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.
ORCID: 0000-0001-8441-1226

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Protéines ADAMTS › Proteolysis of fibrillin-2 microfibrils is...
questionsmedicales.fr › Eucaryotes › Animaux › Proteolysis of fibrillin-2 microfibrils is...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Fibrillines › Fibrilline-1 › Proteolysis of fibrillin-2 microfibrils is...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Fibrillines › Fibrilline-2 › Proteolysis of fibrillin-2 microfibrils is...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Fibrillines › Proteolysis of fibrillin-2 microfibrils is...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Proteolysis of fibrillin-2 microfibrils is...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace extracellulaire › Matrice extracellulaire › Microfibrilles › Proteolysis of fibrillin-2 microfibrils is...
questionsmedicales.fr › Métabolisme › Protéolyse › Proteolysis of fibrillin-2 microfibrils is...