Staging right heart failure in patients with tricuspid regurgitation undergoing tricuspid surgery.


Journal

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
ISSN: 1873-734X
Titre abrégé: Eur J Cardiothorac Surg
Pays: Germany
ID NLM: 8804069

Informations de publication

Date de publication:
11 07 2022
Historique:
received: 21 11 2021
revised: 26 03 2022
accepted: 28 04 2022
pubmed: 6 5 2022
medline: 16 7 2022
entrez: 5 5 2022
Statut: ppublish

Résumé

This study evaluated the prognostic value of staging right heart failure in patients with significant tricuspid regurgitation (TR) undergoing tricuspid valve (TV) surgery. Patients with significant TR who underwent TV surgery were divided into 4 right heart failure stages according to the presence of right ventricular (RV) dysfunction and clinical signs of right heart failure: stage 1 was defined as no RV dysfunction and no signs of right heart failure; stage 2 indicated RV dysfunction without signs of right heart failure; stage 3 included RV dysfunction and signs of right heart failure; and stage 4 was defined as RV dysfunction and refractory signs of right heart failure at rest. A total of 278 patients [mean age 64 (12), 49% males] were included, of whom 34 (12%) patients were classified as stages 1 and 2, 141 (51%) as stage 3 and 103 (37%) as stage 4 right heart failure. The majority of patients (91%) had TV surgery concomitant to left-sided valve surgery or coronary artery bypass grafting and 95% underwent TV annuloplasty. Cumulative survival rates were 89%, 78% and 61% at 1 month, 1 year and 5 years, respectively. Stages 1 and 2 and stage 3 were independently associated with better survival compared to stage 4 (hazard ratio: 0.391 [95% confidence interval: 0.186-0.823] and 0.548 [95% confidence interval: 0.369-0.813], respectively). Patients with significant TR undergoing TV surgery and diagnosed without advanced right heart failure have better survival as compared to patients with right heart failure.

Identifiants

pubmed: 35511132
pii: 6576630
doi: 10.1093/ejcts/ezac290
pmc: PMC9789688
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentIn

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

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Auteurs

Xavier Galloo (X)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.
Department of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.

Jan Stassen (J)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.

Steele C Butcher (SC)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.
Department of Cardiology, Royal Perth Hospital, Perth, Australia.

Maria Chiara Meucci (MC)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.
Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

Marlieke F Dietz (MF)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.

Bart J A Mertens (BJA)

Department of Bioinformatics, Bioinformatics Centre of Expertise, Leiden University Medical Centre, Leiden, Netherlands.

Edgard A Prihadi (EA)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.
Hartcentrum, Ziekenhuis Netwerk Antwerpen (ZNA) Middelheim, Antwerp, Belgium.

Pieter van der Bijl (P)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.

Nina Ajmone Marsan (N)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.

Jerry Braun (J)

Department of Cardio-Thoracic Surgery, Leiden University Medical Centre, Leiden, Netherlands.

Jeroen J Bax (JJ)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.
Heart Centre, University of Turku and Turku University Hospital, Turku, Finland.

Victoria Delgado (V)

Department of Cardiology, Leiden University Medical Centre, Leiden, Netherlands.

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