The β2
Autosomal dominant sleep-related hypermotor epilepsy
CHRNB2
EPSC
M2
Nicotinic acetylcholine receptors
Nocturnal frontal lobe epilepsy
Synaptogenesis
Journal
Progress in neurobiology
ISSN: 1873-5118
Titre abrégé: Prog Neurobiol
Pays: England
ID NLM: 0370121
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
received:
02
07
2021
revised:
02
04
2022
accepted:
28
04
2022
pubmed:
6
5
2022
medline:
9
6
2022
entrez:
5
5
2022
Statut:
ppublish
Résumé
Mutant subunits of the neuronal nicotinic ACh receptor (nAChR) can cause Autosomal Dominant Sleep-related Hypermotor Epilepsy (ADSHE), characterized by frontal seizures during non-rapid eye movement (NREM) sleep. We studied the cellular bases of the pathogenesis in brain slices from mice conditionally expressing the ADSHE-linked β2
Identifiants
pubmed: 35513164
pii: S0301-0082(22)00065-X
doi: 10.1016/j.pneurobio.2022.102279
pii:
doi:
Substances chimiques
Receptors, Nicotinic
0
Somatostatin
51110-01-1
Nicotine
6M3C89ZY6R
Acetylcholine
N9YNS0M02X
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102279Informations de copyright
Copyright © 2022 Elsevier Ltd. All rights reserved.