Case Report: Therapeutic Use of Ibrutinib in a Patient With Schnitzler Syndrome.
Bruton tyrosine kinase inhibitor
Schnitzler syndrome
case report
ibrutinib
interleukin-1
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2022
2022
Historique:
received:
11
03
2022
accepted:
22
03
2022
entrez:
6
5
2022
pubmed:
7
5
2022
medline:
10
5
2022
Statut:
epublish
Résumé
Schnitzler syndrome is a rare adult-onset acquired autoinflammatory disorder typically characterized by chronic urticarial rash and immunoglobulin M (IgM) (rarely IgG) monoclonal gammopathy. Its clinical symptoms usually respond well to interleukin-1 blockade therapy, which, however, does not impact the underlying monoclonal gammopathy. Herein, we described a female patient who presented with urticarial rash, recurrent fevers, and fatigue for 7 years. Laboratory investigations revealed IgMκ monoclonal protein and
Identifiants
pubmed: 35514998
doi: 10.3389/fimmu.2022.894464
pmc: PMC9065412
doi:
Substances chimiques
Antibodies, Monoclonal
0
Piperidines
0
ibrutinib
1X70OSD4VX
Adenine
JAC85A2161
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
894464Informations de copyright
Copyright © 2022 Huang, Wang, Yu, Mao, Wang, Li and Li.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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