Osteoarthritis of the Knee in Middle-age Athletes: Many Measures are Practiced, but Lack Sound Scientific Evidence.


Journal

Sports medicine and arthroscopy review
ISSN: 1538-1951
Titre abrégé: Sports Med Arthrosc Rev
Pays: United States
ID NLM: 9315689

Informations de publication

Date de publication:
01 Jun 2022
Historique:
entrez: 9 5 2022
pubmed: 10 5 2022
medline: 12 5 2022
Statut: ppublish

Résumé

Osteoarthritis of the knee generally affects individuals from the fifth decade, the typical age of middle-age athletes. In the early stages, management is conservative and multidisciplinary. It is advisable to avoid sports with high risk of trauma, but it is important that patients continue to be physically active. Conservative management offers several options; however, it is unclear which ones are really useful. This narrative review briefly reports the conservative options for which there is no evidence of effectiveness, or there is only evidence of short-term effectiveness.

Identifiants

pubmed: 35533062
doi: 10.1097/JSA.0000000000000341
pii: 00132585-202206000-00006
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102-110

Informations de copyright

Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure: The authors declare no conflict of interest.

Références

Goldring MB, Goldring SR. Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis. Ann N Y Acad Sci. 2010;1192:230–237.
Kellgren JH, Lawrence JS, Bier F. Genetic factors in generalized osteo-arthrosis. Ann Rheum Dis. 1963;22:237–255.
Valdes AM, Spector TD. Genetic epidemiology of hip and knee osteoarthritis. Nat Rev Rheumatol. 2011;7:23–32.
Musumeci G, Aiello FC, Szychlinska MA, et al. Osteoarthritis in the XXIst century: risk factors and behaviours that influence disease onset and progression. Int J Mol Sci. 2015;16:6093–6112.
Blagojevic M, Jinks C, Jeffery A, et al. Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage. 2010;18:24–33.
Deshpande BR, Katz JN, Solomon DH, et al. Number of persons with symptomatic knee osteoarthritis in the US: impact of race and ethnicity, age, sex, and obesity. Arthritis Care & Research. 2016;68:1743–1750.
Cruz-Almeida Y, Sibille KT, Goodin BR, et al. Racial and ethnic differences in older adults with knee osteoarthritis. Arthritis & Rheumatol (Hoboken, NJ). 2014;66:1800–1810.
Gandhi R, Wasserstein D, Razak F, et al. BMI independently predicts younger age at hip and knee replacement. Obesity (Silver Spring, Md). 2010;18:2362–2366.
Klussmann A, Gebhardt H, Nübling M, et al. Individual and occupational risk factors for knee osteoarthritis: results of a case-control study in Germany. Arthritis Res Ther. 2010;12:R88.
Joseph GB, Nevitt MC, McCulloch CE, et al. Associations between molecular biomarkers and MR-based cartilage composition and knee joint morphology: data from the Osteoarthritis Initiative. Osteoarthritis and Cartilage. 2018;26:1070–1077.
Belo JN, Berger MY, Reijman M, et al. Prognostic factors of progression of osteoarthritis of the knee: a systematic review of observational studies. Arthritis Rheum. 2007;57:13–26.
Bortoluzzi A, Furini F, Scirè CA. Osteoarthritis and its management—epidemiology, nutritional aspects and environmental factors. Autoimmun Rev. 2018;17:1097–1104.
Cibere J, Zhang H, Thorne A, et al. Association of clinical findings with pre-radiographic and radiographic knee osteoarthritis in a population-based study. Arthritis Care Res (Hoboken). 2010;62:1691–1698.
Bijlsma JWJ, Knahr K. Strategies for the prevention and management of osteoarthritis of the hip and knee. Best Pract Res Clin Rheumatol. 2007;21:59–76.
Muthuri SG, McWilliams DF, Doherty M, et al. History of knee injuries and knee osteoarthritis: a meta-analysis of observational studies. Osteoarthr Cartil. 2011;19:1286–1293.
Cooper C, Snow S, McAlindon TE, et al. Risk factors for the incidence and progression of radiographic knee osteoarthritis. Arthritis Rheum. 2000;43:995–1000.
Wilson MG, Michet CJ, Ilstrup DM, et al. Idiopathic symptomatic osteoarthritis of the hip and knee: a population-based incidence study. Mayo Clin Proc. 1990;65:1214–1221.
Pal CP, Singh P, Chaturvedi S, et al. Epidemiology of knee osteoarthritis in India and related factors. Indian J Orthop. 2016;50:518–522.
Kodama R, Muraki S, Oka H, et al. Prevalence of hand osteoarthritis and its relationship to hand pain and grip strength in Japan: the third survey of the ROAD study. Mod Rheumatol. 2016;26:767–773.
Davatchi F, Sandoughi M, Moghimi N, et al. Epidemiology of rheumatic diseases in Iran from analysis of four COPCORD studies. Int J Rheum Dis. 2016;19:1056–1062.
Alshami AM. Knee osteoarthritis related pain: a narrative review of diagnosis and treatment. Int J Health Sci (Qassim). 2014;8:85–104.
Driban JB, Hootman JM, Sitler MR, et al. Is participation in certain sports associated with knee osteoarthritis? A systematic review. J Athl Train. 2017;52:497–506.
Roos H, Lindberg H, Gärdsell P, et al. The prevalence of gonarthrosis and its relation to meniscectomy in former soccer players. Am J Sports Med. 1994;22:219–222.
Moretz JA, Harlan SD, Goodrich J, et al. Long-term followup of knee injuries in high school football players. Am J Sports Med. 1984;12:298–300.
Reynard LN, Loughlin J. Genetics and epigenetics of osteoarthritis. Maturitas. 2012;71:200–204.
Bruns J, Volkmer M, Luessenhop S. Pressure distribution in the knee joint. Arch Orthop Trauma Surg. 1994;113:204–209.
Lohmander LS, Atley LM, Pietka TA, et al. The release of crosslinked peptides from type II collagen into human synovial fluid is increased soon after joint injury and in osteoarthritis. Arthritis Rheum. 2003;48:3130–3139.
Kujala UM, Kettunen J, Paananen H, et al. Knee osteoarthritis in former runners, soccer players, weight lifters, and shooters. Arthritis and Rheumatism. 1995;38:539–546.
Andriacchi TP, Mündermann A, Smith RL, et al. A framework for the in vivo pathomechanics of osteoarthritis at the knee. Annals of Biomedical Engineering. 2004;32:447–457.
Madaleno FO, Santos BA, Araújo VL, et al. Prevalence of knee osteoarthritis in former athletes: a systematic review with meta-analysis. Braz J Phys Ther. 2018;22:437–451.
Sharma L, Kapoor D, Issa S. Epidemiology of osteoarthritis: an update. Current Opinion in Rheumatology. 2006;18:147–156.
Woolf AD. Driving musculoskeletal health for Europe: EUMUSC.NET. Reumatismo. 2011;63:1–4.
Stevenson JD, Roach R. The benefits and barriers to physical activity and lifestyle interventions for osteoarthritis affecting the adult knee. J Orthop Surg Res. 2012;7:15.
Øiestad BE, White DK, Booton R, et al. Longitudinal course of physical function in people with symptomatic knee osteoarthritis: data from the multicenter osteoarthritis study and the osteoarthritis initiative. Arthritis Care & Research. 2016;68:325–331.
Veronese N, Stubbs B, Solmi M, et al. Association between lower limb osteoarthritis and incidence of depressive symptoms: data from the osteoarthritis initiative. Age Ageing. 2017;46:470–476.
WOMAC-AUSCAN-Osteoarthritis Global Index. Available at: http://www.womac.com/ . Accessed October 12, 2020.
Bannuru RR, Osani MC, Vaysbrot EE, et al. OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis Cartilage. 2019;27:1578–1589.
Zhang W, Moskowitz RW, Nuki G, et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthr Cartil. 2008;16:137–162.
Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;n71:372.
Deyle GD, Henderson NE, Matekel RL, et al. Effectiveness of manual physical therapy and exercise in osteoarthritis of the knee. A randomized, controlled trial. Ann Intern Med. 2000;132:173–181.
French HP, Brennan A, White B, et al. Manual therapy for osteoarthritis of the hip or knee—a systematic review. Man Ther. 2011;16:109–117.
Xu Q, Chen B, Wang Y, et al. The effectiveness of manual therapy for relieving pain, stiffness, and dysfunction in knee osteoarthritis: a systematic review and meta-analysis. Pain Physician. 2017;20:229–243.
Anwer S, Alghadir A, Zafar H, et al. Effects of orthopaedic manual therapy in knee osteoarthritis: a systematic review and meta-analysis. Physiotherapy. 2018;104:264–276.
Felson DT, Zhang Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum. 1998;41:1343–1355.
Abbott JH, Robertson MC, Chapple C, et al. Manual therapy, exercise therapy, or both, in addition to usual care, for osteoarthritis of the hip or knee: a randomized controlled trial. 1: clinical effectiveness. Osteoarthritis Cartilage. 2013;21:525–534.
Kappetijn O, van Trijffel E, Lucas C. Efficacy of passive extension mobilization in addition to exercise in the osteoarthritic knee: an observational parallel-group study. Knee. 2014;21:703–709.
Brosseau L, Wells GA, Tugwell P, et al. Ottawa panel evidence-based clinical practice guidelines for therapeutic exercises and manual therapy in the management of osteoarthritis. Phys Ther. 2005;85:907–971.
Anwer S, Alghadir A, Brismée J-M. Effect of home exercise program in patients with knee osteoarthritis: a systematic review and meta-analysis. J Geriatr Phys Ther. 2016;39:38–48.
Hootman JM, FitzGerald S, Macera CA, et al. Lower extremity muscle strength and risk of self-reported hip or knee osteoarthritis. J Phys Act Health. 2004;1:321–330.
Segal NA, Glass NA, Torner J, et al. Quadriceps weakness predicts risk for knee joint space narrowing in women in the MOST cohort. Osteoarthritis Cartilage. 2010;18:769–775.
Goh S-L, Persson MSM, Stocks J, et al. Efficacy and potential determinants of exercise therapy in knee and hip osteoarthritis: a systematic review and meta-analysis. Ann Phys Rehabil Med. 2019;62:356–365.
Petersen W, Ellermann A, Henning J, et al. Non-operative treatment of unicompartmental osteoarthritis of the knee: a prospective randomized trial with two different braces-ankle-foot orthosis versus knee unloader brace. Arch Orthop Trauma Surg. 2019;139:155–166.
Laxafoss E, Jacobsen S, Gosvig KK, et al. The alignment of the knee joint in relationship to age and osteoarthritis: the Copenhagen Osteoarthritis Study. Skeletal Radiol. 2013;42:531–540.
van Raaij TM, Reijman M, Brouwer RW, et al. Medial knee osteoarthritis treated by insoles or braces: a randomized trial. Clin Orthop Relat Res. 2010;468:1926–1932.
Duivenvoorden T, Brouwer RW, van Raaij TM, et al. Braces and orthoses for treating osteoarthritis of the knee. Cochrane Database Syst Rev. 2015;2015:CD004020.
Gohal C, Shanmugaraj A, Tate P, et al. Effectiveness of valgus offloading knee braces in the treatment of medial compartment knee osteoarthritis: a systematic review. Sports Health. 2018;10:500–514.
Fantini Pagani CH, Potthast W, Brüggemann G-P. The effect of valgus bracing on the knee adduction moment during gait and running in male subjects with varus alignment. Clin Biomech (Bristol, Avon). 2010;25:70–76.
Menger B, Kannenberg A, Petersen W, et al. Effects of a novel foot-ankle orthosis in the non-operative treatment of unicompartmental knee osteoarthritis. Arch Orthop Trauma Surg. 2016;136:1281–1287.
Hsieh R-L, Lee W-C. Clinical effects of lateral wedge arch support insoles in knee osteoarthritis: a prospective double-blind randomized study. Medicine (Baltimore). 2016;95:e3952.
Fernandes L, Hagen KB, Bijlsma JWJ, et al. EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis. Ann Rheum Dis. 2013;72:1125–1135.
Hinman RS, Bowles KA, Bennell KL. Laterally wedged insoles in knee osteoarthritis: do biomechanical effects decline after one month of wear? BMC Musculoskelet Disord. 2009;10:146.
Crenshaw SJ, Pollo FE, Calton EF. Effects of lateral-wedged insoles on kinetics at the knee. Clin Orthop Relat Res. 2000:185–192.
Xing F, Lu B, Kuang M-J, et al. A systematic review and meta-analysis into the effect of lateral wedge arch support insoles for reducing knee joint load in patients with medial knee osteoarthritis. Medicine (Baltimore). 2017;96:e7168.
Shaw KE, Charlton JM, Perry CKL, et al. The effects of shoe-worn insoles on gait biomechanics in people with knee osteoarthritis: a systematic review and meta-analysis. Br J Sports Med. 2018;52:238–253.
Zafar AQ, Zamani R, Akrami M. The effectiveness of foot orthoses in the treatment of medial knee osteoarthritis: a systematic review. Gait Posture. 2020;76:238–251.
Jones RK, Chapman GJ, Parkes MJ, et al. The effect of different types of insoles or shoe modifications on medial loading of the knee in persons with medial knee osteoarthritis: a randomised trial. J Orthop Res. 2015;33:1646–1654.
Arnold JB. Lateral wedge insoles for people with medial knee osteoarthritis: one size fits all, some or none? Osteoarthritis Cartilage. 2016;24:193–195.
Kamper SJ, Henschke N. Kinesio taping for sports injuries. Br J Sports Med. 2013;47:1128–1129.
Han J-W, Lee D-K, Park C-B. The immediate effects of taping therapy on knee pain and depression in patients with degenerative arthritis. J Phys Ther Sci. 2018;30:704–706.
Woźniak-Czekierda W, Woźniak K, Hadamus A, et al. Use of kinesiology taping in rehabilitation after knee arthroplasty: a randomised clinical study. Ortop Traumatol Rehabil. 2017;19:461–468.
Li X, Zhou X, Liu H, et al. Effects of elastic therapeutic taping on knee osteoarthritis: a systematic review and meta-analysis. Aging Dis. 2018;9:296–308.
Lu Z, Li X, Chen R, et al. Kinesio taping improves pain and function in patients with knee osteoarthritis: a meta-analysis of randomized controlled trials. Int J Surg. 2018;59:27–35.
Rahlf AL, Braumann K-M, Zech A. Kinesio taping improves perceptions of pain and function of patients with knee osteoarthritis: a randomized, controlled trial. J Sport Rehabil. 2019;28:481–487.
Melzack R, Wall PD. Pain mechanisms: a new theory. Science. 1965;150:971–979.
Babault N, Cometti C, Maffiuletti NA, et al. Does electrical stimulation enhance post-exercise performance recovery? Eur J Appl Physiol. 2011;111:2501–2507.
Zeng C, Li H, Yang T, et al. Electrical stimulation for pain relief in knee osteoarthritis: systematic review and network meta-analysis. Osteoarthritis Cartilage. 2015;23:189–202.
Poitras S, Brosseau L. Evidence-informed management of chronic low back pain with transcutaneous electrical nerve stimulation, interferential current, electrical muscle stimulation, ultrasound, and thermotherapy. Spine J. 2008;8:226–233.
Goats GC. Interferential current therapy. Br J Sports Med. 1990;24:87–92.
McAlindon TE, Bannuru RR, Sullivan MC, et al. OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis Cartilage. 2014;22:363–388.
Davis AM, MacKay C. Osteoarthritis year in review: outcome of rehabilitation. Osteoarthritis Cartilage. 2013;21:1414–1424.
Park SH, Hwangbo G. Effects of combined application of progressive resistance training and Russian electrical stimulation on quadriceps femoris muscle strength in elderly women with knee osteoarthritis. J Phys Ther Sci. 2015;27:729–731.
Hassan BS, Mockett S, Doherty M. Static postural sway, proprioception, and maximal voluntary quadriceps contraction in patients with knee osteoarthritis and normal control subjects. Ann Rheum Dis. 2001;60:612–618.
Cherian JJ, Jauregui JJ, Leichliter AK, et al. The effects of various physical non-operative modalities on the pain in osteoarthritis of the knee. Bone Joint J. 2016;98-B:89–94.
Novak S, Guerron G, Zou Z, et al. New guidelines for electrical stimulation parameters in adult patients with knee osteoarthritis based on a systematic review of the current literature. Am J Phys Med Rehabil. 2020;99:682–688.
de Oliveira Melo M, Pompeo KD, Baroni BM, et al. Effects of neuromuscular electrical stimulation and low-level laser therapy on neuromuscular parameters and health status in elderly women with knee osteoarthritis: a randomized trial. J Rehabil Med. 2016;48:293–299.
Hasan S. Quadriceps femoris strength training: effect of neuromuscular electrical stimulation vs isometric exercise in osteoarthritis of knee. Ind Jour of Physioth and Occupat Therapy - An Inter Jour. 2015;9:129.
Rutjes AW, Nüesch E, Sterchi R, et al. Transcutaneous electrostimulation for osteoarthritis of the knee. Cochrane Database Syst Rev. 2009;2009:CD002823.
Chen L-X, Zhou Z-R, Li Y-L, et al. Transcutaneous electrical nerve stimulation in patients with knee osteoarthritis: evidence from randomized-controlled trials. Clin J Pain. 2016;32:146–154.
Vance CGT, Rakel BA, Blodgett NP, et al. Effects of transcutaneous electrical nerve stimulation on pain, pain sensitivity, and function in people with knee osteoarthritis: a randomized controlled trial. Phys Ther. 2012;92:898–910.
Law PPW, Cheing GLY, Tsui AYY. Does transcutaneous electrical nerve stimulation improve the physical performance of people with knee osteoarthritis? J Clin Rheumatol. 2004;10:295–299.
Alayat MSM, Aly THA, Elsayed AEM, et al. Efficacy of pulsed Nd:YAG laser in the treatment of patients with knee osteoarthritis: a randomized controlled trial. Lasers Med Sci. 2017;32:503–511.
Ebid AA, Ibrahim AR, Omar MT, et al. Long-term effects of pulsed high-intensity laser therapy in the treatment of post-burn pruritus: a double-blind, placebo-controlled, randomized study. Lasers Med Sci. 2017;32:693–701.
Zati A, Valent A. Terapia fisica: nuove tecnologie in medicina riabilitativa, 2nd Edition. Minerva Medica: 2017.
Wyszyńska J, Bal-Bocheńska M. Efficacy of high-intensity laser therapy in treating knee osteoarthritis: a first systematic review. Photomed Laser Surg. 2018;36:343–353.
Kheshie AR, Alayat MSM, Ali MME. High-intensity versus low-level laser therapy in the treatment of patients with knee osteoarthritis: a randomized controlled trial. Lasers Med Sci. 2014;29:1371–1376.
Choi H-W, Lee J, Lee S, et al. Effects of high intensity laser therapy on pain and function of patients with chronic back pain. J Phys Ther Sci. 2017;29:1079–1081.
Angelova A, Ilieva EM. Effectiveness of high intensity laser therapy for reduction of pain in knee osteoarthritis. Pain Res Manag. 2016;2016:9163618.
Lyss G, Schmidt TJ, Merfort I, et al. Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB. Biol Chem. 1997;378:951–961.
Hausen BM. Arnica allergy. Hautarzt. 1980;31:10–17.
Cameron M, Chrubasik S. Topical herbal therapies for treating osteoarthritis. Cochrane Database Syst Rev. 2013;5:CD010538.
Knuesel O, Weber M, Suter A. Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial. Adv Therapy. 2002;19:209–218.
Bannuru RR, Natov NS, Obadan IE, et al. Therapeutic trajectory of hyaluronic acid versus corticosteroids in the treatment of knee osteoarthritis: a systematic review and meta-analysis. Arthritis Rheum. 2009;61:1704–1711.
Bellamy N, Campbell J, Robinson V, et al. Intraarticular corticosteroid for treatment of osteoarthritis of the knee. Cochrane Database Syst Rev. 2006:CD005328.
Behrens F, Shepard N, Mitchell N. Alterations of rabbit articular cartilage by intra-articular injections of glucocorticoids. J Bone Joint Surg Am. 1975;57:70–76.
Behrens F, Shepard N, Mitchell N. Metabolic recovery of articular cartilage after intra-articular injections of glucocorticoid. J Bone Joint Surg Am. 1976;58:1157–1160.
McAlindon TE, LaValley MP, Harvey WF, et al. Effect of intra-articular triamcinolone vs saline on knee cartilage volume and pain in patients with knee osteoarthritis: a randomized clinical trial. JAMA. 2017;317:1967–1975.
Schmidt MB, Chen EH, Lynch SE. A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair. Osteoarthritis Cartilage. 2006;14:403–412.
Sundman EA, Cole BJ, Karas V, et al. The anti-inflammatory and matrix restorative mechanisms of platelet-rich plasma in osteoarthritis. Am J Sports Med. 2014;42:35–41.
Andia I, Maffulli N. Muscle and tendon injuries: the role of biological interventions to promote and assist healing and recovery. Arthroscopy. 2015;31:999–1015.
Andia I, Perez-Valle A, Del Amo C, et al. Freeze-drying of platelet-rich plasma: the quest for standardization. Int J Mol Sci. 2020;21:E6904.
Baranova IV. The use of the functional state of the joints for the estimation of the effectiveness of the application of oxygen/ozone therapy for the rehabilitative treatment of the patients suffering from knee arthritis. Vopr Kurortol Fizioter Lech Fiz Kult. 2018;95:42–48.
Javadi Hedayatabad J, Kachooei AR, Taher Chaharjouy N, et al. The effect of ozone (O3) versus hyaluronic acid on pain and function in patients with knee osteoarthritis: a systematic review and meta-analysis. Arch Bone Jt Surg. 2020;8:343–354.
Duymus TM, Mutlu S, Dernek B, et al. Choice of intra-articular injection in treatment of knee osteoarthritis: platelet-rich plasma, hyaluronic acid or ozone options. Knee Surg Sports Traumatol Arthrosc. 2017;25:485–492.
Li Q, Qi X, Zhang Z. Intra-articular oxygen-ozone versus hyaluronic acid in knee osteoarthritis: a meta-analysis of randomized controlled trials. Int J Surg. 2018;58:3–10.
Hassan F, Murrell WD, Refalo A, et al. Alternatives to biologics in management of knee osteoarthritis: a systematic review. Sports Med Arthrosc Rev. 2018;26:79–85.
Boon AJ, Smith J, Dahm DL, et al. Efficacy of intra-articular botulinum toxin type A in painful knee osteoarthritis: a pilot study. PM R. 2010;2:268–276.
Rezasoltani Z, Azizi S, Najafi S, et al. Physical therapy, intra-articular dextrose prolotherapy, botulinum neurotoxin, and hyaluronic acid for knee osteoarthritis: randomized clinical trial. Int J Rehabil Res. 2020;43:219–227.
McAlindon TE, Schmidt U, Bugarin D, et al. Efficacy and safety of single-dose onabotulinumtoxin A in the treatment of symptoms of osteoarthritis of the knee: results of a placebo-controlled, double-blind study. Osteoarthritis Cartilage. 2018;26:1291–1299.
Mendes JG, Natour J, Nunes-Tamashiro JC, et al. Comparison between intra-articular Botulinum toxin type A, corticosteroid, and saline in knee osteoarthritis: a randomized controlled trial. Clin Rehabil. 2019;33:1015–1026.
Zhai S, Huang B, Yu K. The efficacy and safety of Botulinum Toxin Type A in painful knee osteoarthritis: a systematic review and meta-analysis. J Int Med Res. 2020;48:300060519895868.
Jensen KT, Rabago DP, Best TM, et al. Early inflammatory response of knee ligaments to prolotherapy in a rat model. J Orthop Res. 2008;26:816–823.
Farpour HR, Fereydooni F. Comparative effectiveness of intra-articular prolotherapy versus peri-articular prolotherapy on pain reduction and improving function in patients with knee osteoarthritis: a randomized clinical trial. Electron Physician. 2017;9:5663–5669.
Sert AT, Sen EI, Esmaeilzadeh S, et al. The effects of dextrose prolotherapy in symptomatic knee osteoarthritis: a randomized controlled study. J Altern Complement Med. 2020;26:409–417.
Rahimzadeh P, Imani F, Faiz SHR, et al. The effects of injecting intra-articular platelet-rich plasma or prolotherapy on pain score and function in knee osteoarthritis. Clin Interv Aging. 2018;13:73–79.
Apaydin H, Bazancir Z, Altay Z. Injection therapy in patients with lateral epicondylalgia: hyaluronic acid or dextrose prolotherapy? A single-blind, randomized clinical trial. J Altern Complement Med. 2020;26:1169–1175.
Arnold BL, Wright CJ, Ross SE. Functional ankle instability and health-related quality of life. J Athl Train. 2011;46:634–641.
Farivar S, Malekshahabi T, Shiari R. Biological effects of low level laser therapy. J Lasers Med Sci. 2014;5:58–62.
Rayegani SM, Raeissadat SA, Heidari S, et al. Safety and effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis. J Lasers Med Sci. 2017;8:S12–S19.
Stausholm MB, Naterstad IF, Joensen J, et al. Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials. BMJ Open. 2019;9:e031142.
Kolasinski SL, Neogi T, Hochberg MC, et al. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis Care Res (Hoboken). 2020;72:149–162.
Chou R, McDonagh MS, Nakamoto E, et al. Analgesics for osteoarthritis: an update of the 2006 comparative effectiveness review. Rockville, MD: Agency for Healthcare Research and Quality. 2011. Available at: http://www.ncbi.nlm.nih.gov/books/NBK65646/ . Accessed February 11, 2021.
Bellamy N, Campbell J, Robinson V, et al. Viscosupplementation for the treatment of osteoarthritis of the knee. Cochrane Database Syst Rev. 2006:CD005321.
Maheu E, Rannou F, Reginster J-Y. Efficacy and safety of hyaluronic acid in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016;45:S28–S33.
Ishijima M, Nakamura T, Shimizu K, et al. Intra-articular hyaluronic acid injection versus oral non-steroidal anti-inflammatory drug for the treatment of knee osteoarthritis: a multi-center, randomized, open-label, non-inferiority trial. Arthritis Res Ther. 2014;16:R18.
Altman RD, Bedi A, Karlsson J, et al. Product differences in intra-articular hyaluronic acids for osteoarthritis of the knee. Am J Sports Med. 2016;44:2158–2165.
Hermans J, Bierma-Zeinstra SMA, Bos PK, et al. The effectiveness of high molecular weight hyaluronic acid for knee osteoarthritis in patients in the working age: a randomised controlled trial. BMC Musculoskelet Disord. 2019;20:196.
Lin K-Y, Yang C-C, Hsu C-J, et al. Intra-articular injection of platelet-rich plasma is superior to hyaluronic acid or saline solution in the treatment of mild to moderate knee osteoarthritis: a randomized, double-blind, triple-parallel, placebo-controlled clinical trial. Arthroscopy. 2019;35:106–117.
Lana JFSD, Weglein A, Sampson SE, et al. Randomized controlled trial comparing hyaluronic acid, platelet-rich plasma and the combination of both in the treatment of mild and moderate osteoarthritis of the knee. J Stem Cells Regen Med. 2016;12:69–78.
Görmeli G, Görmeli CA, Ataoglu B, et al. Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis: a randomized, double-blind, placebo-controlled trial. Knee Surg Sports Traumatol Arthrosc. 2017;25:958–965.
Montañez-Heredia E, Irízar S, Huertas PJ, et al. Intra-articular injections of platelet-rich plasma versus hyaluronic acid in the treatment of osteoarthritic knee pain: a randomized clinical trial in the context of the spanish national health care system. Int J Mol Sci . 2016;17:1064.
Di Y, Han C, Zhao L, et al. Is local platelet-rich plasma injection clinically superior to hyaluronic acid for treatment of knee osteoarthritis? A systematic review of randomized controlled trials. Arthritis Res Ther. 2018;20:128.
Di Martino A, Di Matteo B, Papio T, et al. Platelet-rich plasma versus hyaluronic acid injections for the treatment of knee osteoarthritis: results at 5 years of a double-blind, randomized controlled trial. Am J Sports Med. 2019;47:347–354.
Brown GA. AAOS clinical practice guideline: treatment of osteoarthritis of the knee: evidence-based guideline, 2nd ed. J Am Acad Orthop Surg. 2013;21:577–579.
Bocci VA. Scientific and medical aspects of ozone therapy. State of the art. Arch Med Res. 2006;37:425–435.
Raeissadat SA, Tabibian E, Rayegani SM, et al. An investigation into the efficacy of intra-articular ozone (O2-O3) injection in patients with knee osteoarthritis: a systematic review and meta-analysis. J Pain Res. 2018;11:2537–2550.
Courseau M, Salle PV, Ranoux D, et al. Efficacy of intra-articular botulinum toxin in osteoarticular joint pain: a meta-analysis of randomized controlled trials. Clin J Pain. 2018;34:383–389.
Krug HE, Frizelle S, McGarraugh P, et al. Pain behavior measures to quantitate joint pain and response to neurotoxin treatment in murine models of arthritis. Pain Med. 2009;10:1218–1228.
Arias-Vázquez PI, Tovilla-Zárate CA, Legorreta-Ramírez BG, et al. Prolotherapy for knee osteoarthritis using hypertonic dextrose vs other interventional treatments: systematic review of clinical trials. Adv Rheumatol. 2019;59:39.
Aicher WK, Bühring H-J, Hart M, et al. Regeneration of cartilage and bone by defined subsets of mesenchymal stromal cells—potential and pitfalls. Adv Drug Deliv Rev. 2011;63:342–351.
Caplan AI, Dennis JE. Mesenchymal stem cells as trophic mediators. J Cell Biochem. 2006;98:1076–1084.
Migliorini F, Rath B, Colarossi G, et al. Improved outcomes after mesenchymal stem cells injections for knee osteoarthritis: results at 12-months follow-up: a systematic review of the literature. Arch Orthop Trauma Surg. 2020;140:853–868.
Garza JR, Campbell RE, Tjoumakaris FP, et al. Clinical efficacy of intra-articular mesenchymal stromal cells for the treatment of knee osteoarthritis: a double-blinded prospective randomized controlled clinical trial. Am J Sports Med. 2020;48:588–598.
Kim SH, Djaja YP, Park Y-B, et al. Intra-articular injection of culture-expanded mesenchymal stem cells without adjuvant surgery in knee osteoarthritis: a systematic review and meta-analysis. Am J Sports Med. 2020;48:2839–2849.
Felson DT. Preventing knee and hip osteoarthritis. Bull Rheum Dis. 1998;47:1–4.
Felson DT, Zhang Y, Anthony JM, et al. Weight loss reduces the risk for symptomatic knee osteoarthritis in women. The Framingham Study. Ann Intern Med. 1992;116:535–539.
Hochberg MC Hascall VC, Kuettner KE. Prevention of lower limb osteoarthritis: data from the Johns Hopkins Precursors Study. The Many Faces of Osteoarthritis. Basel: Birkhäuser Basel. 31–37.
Manninen P, Riihimäki H, Heliövaara M, et al. Overweight, gender and knee osteoarthritis. Int J Obes Relat Metab Disord. 1996;20:595–597.
Dargo L, Robinson KJ, Games KE. Prevention of knee and anterior cruciate ligament injuries through the use of neuromuscular and proprioceptive training: an evidence-based review. J Athl Train. 2017;52:1171–1172.
Kakavas G, Malliaropoulos N, Pruna R, et al. Neuroplasticity and anterior cruciate ligament injury. Indian J Orthop. 2020;54:275–280.

Auteurs

Marco Quaranta (M)

Department of Musculoskeletal Disorders, Faculty of Medicine and Surgery, University of Salerno, Baronissi.
Clinica Ortopedica, Ospedale San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.

Ivano Riccio (I)

Department of Musculoskeletal Disorders, Faculty of Medicine and Surgery, University of Salerno, Baronissi.
Clinica Ortopedica, Ospedale San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.

Francesco Oliva (F)

Department of Musculoskeletal Disorders, Faculty of Medicine and Surgery, University of Salerno, Baronissi.
Clinica Ortopedica, Ospedale San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.

Nicola Maffulli (N)

Department of Musculoskeletal Disorders, Faculty of Medicine and Surgery, University of Salerno, Baronissi.
Clinica Ortopedica, Ospedale San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.
Barts and the London School of Medicine and Dentistry, Centre for Sports and Exercise Medicine, Mile End Hospital, Queen Mary University of London, London.
Faculty of Medicine, School of Pharmacy and Bioengineering, Guy Hilton Research Centre, Keele University, Stoke-on-Trent, England.

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