Management of atypical uremic hemolytic syndrome in pregnant patient.
Embarazo
Haemolytic uremic syndrome
Microangiopatía trombótica
Pregnancy
Síndrome hemolítico urémico
Trombotic microangiopathy
Journal
Revista espanola de anestesiologia y reanimacion
ISSN: 2341-1929
Titre abrégé: Rev Esp Anestesiol Reanim (Engl Ed)
Pays: Spain
ID NLM: 101778594
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
15
05
2020
accepted:
14
12
2020
pubmed:
11
5
2022
medline:
1
6
2022
entrez:
10
5
2022
Statut:
ppublish
Résumé
Atypical uremic haemolytic syndrome is a variant of thrombotic micro-andiopathy characterized by non-autoimmune hemolytic anemia, thrombocytopenia and acute renal failure as a result of excessive activation of the complement. Up to 60% of patients have mutations in the genes that encode the complement system. A disensing factor is required for its manifestation, including gestation. It is an entity with a high morbidity, which can decrease drastically if an early diagnosis is made and appropriate treatment is initiated. Administration of ecuilizumab has demonstrated rapid process disruption, reducing the need for extrarenal purification therapies and improving renal function and patient prognosis.
Identifiants
pubmed: 35537944
pii: S2341-1929(22)00059-2
doi: 10.1016/j.redare.2020.12.008
pii:
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
245-248Informations de copyright
Publicado por Elsevier España, S.L.U.