Long-term trajectories of employment status, workhours and disability support pension status, after a first episode of CNS demyelination.
Multiple sclerosis
disability pension
disease progression
employment
longitudinal studies
risk factors
Journal
Multiple sclerosis (Houndmills, Basingstoke, England)
ISSN: 1477-0970
Titre abrégé: Mult Scler
Pays: England
ID NLM: 9509185
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
pubmed:
14
5
2022
medline:
9
9
2022
entrez:
13
5
2022
Statut:
ppublish
Résumé
People with multiple sclerosis face significant employment-related challenges, with little known of the drivers of these outcomes. We examined prospective trajectories of employment-related outcomes up to 11 years following a first episode of central nervous system (CNS) demyelination (FCD). Participants were aged 18-59 years, at FCD, with at least two observations and were employed at study entry or anytime during follow-up ( Distinct trajectories were identified for employment (4), workhours (4) and DSP (2). Compared with stable full-time, female sex was strongly associated with being in the stable part-time trajectory (risk ratio (RR): 5.35; 95% confidence interval (CI) = 2.56-11.20; These trajectories indicate substantial heterogeneity and the complex impact of MS on employment from its earliest timepoints. Understanding these trends could enable better targeting of interventions to facilitate workforce retention, particularly for females, those with a higher number of comorbidities, more frequent relapses and greater rate of disability accrual.
Sections du résumé
BACKGROUND
People with multiple sclerosis face significant employment-related challenges, with little known of the drivers of these outcomes.
OBJECTIVE
We examined prospective trajectories of employment-related outcomes up to 11 years following a first episode of central nervous system (CNS) demyelination (FCD).
METHODS
Participants were aged 18-59 years, at FCD, with at least two observations and were employed at study entry or anytime during follow-up (
RESULTS
Distinct trajectories were identified for employment (4), workhours (4) and DSP (2). Compared with stable full-time, female sex was strongly associated with being in the stable part-time trajectory (risk ratio (RR): 5.35; 95% confidence interval (CI) = 2.56-11.20;
CONCLUSION
These trajectories indicate substantial heterogeneity and the complex impact of MS on employment from its earliest timepoints. Understanding these trends could enable better targeting of interventions to facilitate workforce retention, particularly for females, those with a higher number of comorbidities, more frequent relapses and greater rate of disability accrual.
Identifiants
pubmed: 35549477
doi: 10.1177/13524585221089900
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1793-1807Investigateurs
Robyn Lucas
(R)
Keith Dear
(K)
Terry Dwyer
(T)
Trevor Kilpatrick
(T)
David Williams
(D)
Cameron Shaw
(C)
Caron Chapman
(C)
Alan Coulthard
(A)
Michael P Pender
(MP)
Patricia Valery
(P)