Genomic diversity across the Rickettsia and 'Candidatus Megaira' genera and proposal of genus status for the Torix group.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
12 05 2022
12 05 2022
Historique:
received:
18
10
2021
accepted:
29
04
2022
entrez:
13
5
2022
pubmed:
14
5
2022
medline:
18
5
2022
Statut:
epublish
Résumé
Members of the bacterial genus Rickettsia were originally identified as causative agents of vector-borne diseases in mammals. However, many Rickettsia species are arthropod symbionts and close relatives of 'Candidatus Megaira', which are symbiotic associates of microeukaryotes. Here, we clarify the evolutionary relationships between these organisms by assembling 26 genomes of Rickettsia species from understudied groups, including the Torix group, and two genomes of 'Ca. Megaira' from various insects and microeukaryotes. Our analyses of the new genomes, in comparison with previously described ones, indicate that the accessory genome diversity and broad host range of Torix Rickettsia are comparable to those of all other Rickettsia combined. Therefore, the Torix clade may play unrecognized roles in invertebrate biology and physiology. We argue this clade should be given its own genus status, for which we propose the name 'Candidatus Tisiphia'.
Identifiants
pubmed: 35551207
doi: 10.1038/s41467-022-30385-6
pii: 10.1038/s41467-022-30385-6
pmc: PMC9098888
doi:
Banques de données
figshare
['10.6084/m9.figshare.14865576.v3', '10.6084/m9.figshare.14865567.v5', '10.6084/m9.figshare.14865570.v4']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2630Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/J017698/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/K501773/1
Pays : United Kingdom
Informations de copyright
© 2022. The Author(s).
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