PDGFRα
Colon
Inhibitory Effects
Interstitial Cells
Peptidergic Neurotransduction
Journal
Cellular and molecular gastroenterology and hepatology
ISSN: 2352-345X
Titre abrégé: Cell Mol Gastroenterol Hepatol
Pays: United States
ID NLM: 101648302
Informations de publication
Date de publication:
2022
2022
Historique:
received:
06
02
2022
revised:
01
05
2022
accepted:
05
05
2022
pubmed:
16
5
2022
medline:
26
7
2022
entrez:
15
5
2022
Statut:
ppublish
Résumé
Platelet-derived growth factor receptor α (PDGFRα)-positive interstitial cells (PIC) are interposed between enteric nerve fibers and smooth muscle cells (SMCs) in the tunica muscularis of the gastrointestinal tract. PIC have robust expression of small conductance Ca Gene expression analysis, Ca Adcyap1r1 (encoding PAC PIC of mouse and human colon utilize PAC
Sections du résumé
BACKGROUND & AIMS
Platelet-derived growth factor receptor α (PDGFRα)-positive interstitial cells (PIC) are interposed between enteric nerve fibers and smooth muscle cells (SMCs) in the tunica muscularis of the gastrointestinal tract. PIC have robust expression of small conductance Ca
METHODS
Gene expression analysis, Ca
RESULTS
Adcyap1r1 (encoding PAC
CONCLUSIONS
PIC of mouse and human colon utilize PAC
Identifiants
pubmed: 35569815
pii: S2352-345X(22)00085-6
doi: 10.1016/j.jcmgh.2022.05.004
pmc: PMC9250024
pii:
doi:
Substances chimiques
Pituitary Adenylate Cyclase-Activating Polypeptide
0
Receptor, Platelet-Derived Growth Factor alpha
EC 2.7.10.1
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
357-373Subventions
Organisme : NIDDK NIH HHS
ID : R01 DK091336
Pays : United States
Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.