Update on the Diagnosis and Treatment of Achalasia.
Achalasia
Botulinum toxin
Deglutition
Deglutition disorders
Heller surgical myotomy
High-resolution esophageal manometry
Peroral endoscopic myotomy
Pneumatic dilation
Journal
Dysphagia
ISSN: 1432-0460
Titre abrégé: Dysphagia
Pays: United States
ID NLM: 8610856
Informations de publication
Date de publication:
04 2023
04 2023
Historique:
received:
16
04
2021
accepted:
04
03
2022
pubmed:
19
5
2022
medline:
15
3
2023
entrez:
18
5
2022
Statut:
ppublish
Résumé
Achalasia is a rare disease of the esophagus with impaired relaxation of the lower esophageal sphincter and aperistalsis. The etiology is unknown but speculations include a viral or autoimmune etiology. All specialists dealing with swallowing and esophageal diseases should recognize the classic symptoms of dysphagia for solids/liquids, regurgitation, and choking, especially at night. High-resolution manometry is critical for the diagnosis with endoscopy and barium esophagram having a supportive role. The disease cannot be cured but most can return to near normal swallowing and a regular diet with appropriate therapy. Treatment includes smooth muscle relaxants, botulinum toxin injections to the lower sphincter, pneumatic dilation, Heller myotomy, and peroral endoscopic myotomy. One treatment does not fit all and a tailored approach through a multidiscipline team will give the best long-term outcomes.
Identifiants
pubmed: 35585208
doi: 10.1007/s00455-022-10435-3
pii: 10.1007/s00455-022-10435-3
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
596-608Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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