Spelling out the roles of individual nucleoporins in nuclear export of mRNA.
Nucleocytoplasmic transport
mRNA biology
super-resolution light microscopy
Journal
Nucleus (Austin, Tex.)
ISSN: 1949-1042
Titre abrégé: Nucleus
Pays: United States
ID NLM: 101518322
Informations de publication
Date de publication:
12 2022
12 2022
Historique:
entrez:
20
5
2022
pubmed:
21
5
2022
medline:
24
5
2022
Statut:
ppublish
Résumé
The Nuclear Pore Complex (NPC) represents a critical passage through the nuclear envelope for nuclear import and export that impacts nearly every cellular process at some level. Recent technological advances in the form of Auxin Inducible Degron (AID) strategies and Single-Point Edge-Excitation sub-Diffraction (SPEED) microscopy have enabled us to provide new insight into the distinct functions and roles of nuclear basket nucleoporins (Nups) upon nuclear docking and export for mRNAs. In this paper, we provide a review of our recent findings as well as an assessment of new techniques, updated models, and future perspectives in the studies of mRNA's nuclear export.
Identifiants
pubmed: 35593254
doi: 10.1080/19491034.2022.2076965
pmc: PMC9132428
doi:
Substances chimiques
Nuclear Pore Complex Proteins
0
RNA, Messenger
0
Types de publication
Journal Article
Review
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
170-193Subventions
Organisme : NIGMS NIH HHS
ID : R35 GM122552
Pays : United States
Références
Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2172-7
pubmed: 16461911
J Biol Chem. 2010 May 28;285(22):16683-92
pubmed: 20371601
Elife. 2015 Dec 17;4:
pubmed: 26673895
Nat Struct Biol. 2000 Oct;7(10):838-42
pubmed: 11017188
Cell. 2006 Dec 29;127(7):1389-400
pubmed: 17190602
Curr Opin Cell Biol. 2019 Jun;58:1-7
pubmed: 30530239
EMBO J. 2001 Oct 15;20(20):5703-14
pubmed: 11598013
Proc Natl Acad Sci U S A. 2012 May 8;109(19):7326-31
pubmed: 22529346
J Cell Biol. 1990 Apr;110(4):883-94
pubmed: 2324201
EMBO J. 1998 Feb 16;17(4):1107-19
pubmed: 9463388
J Biol Chem. 2013 Feb 8;288(6):3952-63
pubmed: 23264634
Cold Spring Harb Perspect Biol. 2010 Oct;2(10):a000562
pubmed: 20630994
Nat Biotechnol. 2013 Mar;31(3):227-9
pubmed: 23360964
EMBO J. 2010 May 19;29(10):1659-73
pubmed: 20407419
Cell. 2007 Aug 10;130(3):405-7
pubmed: 17693250
Nat Rev Mol Cell Biol. 2007 Oct;8(10):761-73
pubmed: 17786152
Nature. 2020 Oct;586(7831):796-800
pubmed: 32879490
Cell. 2002 May 31;109(5):551-62
pubmed: 12062099
Nature. 1995 Aug 24;376(6542):709-12
pubmed: 7651522
Nature. 2015 Oct 1;526(7571):140-143
pubmed: 26416747
J Cell Biol. 2000 Aug 21;150(4):695-706
pubmed: 10952996
Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9512-7
pubmed: 16769882
Nat Protoc. 2021 Jan;16(1):532-560
pubmed: 33318694
Mol Cell Biol. 2002 Jan;22(1):245-56
pubmed: 11739738
Nat Cell Biol. 2006 Jul;8(7):668-76
pubmed: 16783364
J Cell Sci. 1998 Jan;111 ( Pt 2):223-36
pubmed: 9405308
Elife. 2018 Jan 05;7:
pubmed: 29303478
Science. 2008 Nov 28;322(5906):1369-73
pubmed: 18974315
Cell. 1995 Apr 21;81(2):215-22
pubmed: 7736573
Nat Biotechnol. 1996 Mar;14(3):303-8
pubmed: 9630890
Mol Cell Biol. 2001 May;21(10):3405-15
pubmed: 11313466
Mol Biol Cell. 2008 Sep;19(9):3982-96
pubmed: 18596237
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2450-5
pubmed: 12604785
Science. 2016 Jun 17;352(6292):1425-9
pubmed: 27313040
Mol Biol Cell. 2012 Sep;23(18):3673-6
pubmed: 22833564
Annu Rev Biophys. 2012;41:557-84
pubmed: 22577827
Nat Struct Mol Biol. 2018 Dec;25(12):1062-1064
pubmed: 30518846
Nat Cell Biol. 2005 Jul;7(7):719-23
pubmed: 15937477
J Cell Biol. 2016 Aug 29;214(5):529-37
pubmed: 27551060
Structure. 2005 Dec;13(12):1869-79
pubmed: 16338415
Nat Rev Mol Cell Biol. 2010 Jul;11(7):490-501
pubmed: 20571586
Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16251-6
pubmed: 19805289
J Biol Chem. 2012 Nov 9;287(46):38515-22
pubmed: 23007389
EMBO J. 2000 Aug 1;19(15):3918-31
pubmed: 10921874
Nature. 2021 Oct;598(7882):667-671
pubmed: 34646014
EMBO J. 1997 Jun 2;16(11):3256-71
pubmed: 9214641
Mol Cell Proteomics. 2010 Oct;9(10):2205-24
pubmed: 20368288
Nature. 2007 Nov 29;450(7170):695-701
pubmed: 18046406
Traffic. 2005 Mar;6(3):187-98
pubmed: 15702987
Biochem J. 2020 Jan 17;477(1):23-44
pubmed: 31913454
RNA. 2011 Jul;17(7):1344-56
pubmed: 21613532
J Biol Chem. 2001 Mar 2;276(9):6445-52
pubmed: 11104765
Exp Cell Res. 2004 May 15;296(1):12-20
pubmed: 15120988
Mol Cell. 2019 Dec 19;76(6):981-997.e7
pubmed: 31757757
PLoS One. 2011;6(7):e22423
pubmed: 21811608
Cell. 2007 Apr 6;129(1):83-96
pubmed: 17418788
J Cell Biol. 2011 Aug 22;194(4):597-612
pubmed: 21859863
Methods Cell Biol. 2014;122:117-46
pubmed: 24857728
Science. 2016 Apr 15;352(6283):363-5
pubmed: 27081072
RNA. 2000 Jan;6(1):136-58
pubmed: 10668806
J Cell Biol. 2012 Feb 20;196(4):419-34
pubmed: 22331846
J Cell Biol. 1997 Jan 27;136(2):241-50
pubmed: 9015297
Nature. 2006 Jun 8;441(7094):774-8
pubmed: 16760983
J Cell Biol. 2013 Dec 9;203(5):737-46
pubmed: 24297750
Nat Cell Biol. 2006 Jul;8(7):711-6
pubmed: 16783363
Oncogene. 2012 Nov 8;31(45):4803-9
pubmed: 22249246
J Cell Biol. 2016 Oct 10;215(1):57-76
pubmed: 27697925
Cell. 1995 Dec 1;83(5):683-92
pubmed: 8521485
J Biol Chem. 2010 Apr 2;285(14):10841-9
pubmed: 20133940
EMBO J. 1993 Feb;12(2):595-600
pubmed: 8440248
Nucleus. 2016 Sep 2;7(5):430-446
pubmed: 27673359
EMBO J. 2001 Mar 15;20(6):1320-30
pubmed: 11250898
Cell. 2012 Aug 17;150(4):738-51
pubmed: 22901806
Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7305-10
pubmed: 20368455
EMBO Rep. 2000 Jul;1(1):53-8
pubmed: 11256625
Nat Rev Mol Cell Biol. 2004 Oct;5(10):855-61
pubmed: 15459666
Nat Commun. 2018 Jun 18;9(1):2361
pubmed: 29915221
Nat Commun. 2013;4:2414
pubmed: 24008311
Open Biol. 2018 Oct 3;8(10):
pubmed: 30282659
Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):
pubmed: 34504007
Biochem Soc Trans. 2020 Dec 18;48(6):2603-2614
pubmed: 33336681
Science. 2001 Nov 30;294(5548):1895-901
pubmed: 11729309
Nucleic Acids Res. 2012 May;40(10):4562-73
pubmed: 22307388
J Cell Biol. 1997 Jun 2;137(5):1001-16
pubmed: 9166402
Mol Biol Cell. 2003 May;14(5):1923-40
pubmed: 12802065
PLoS One. 2012;7(1):e29921
pubmed: 22253824
Sci Rep. 2017 Nov 17;7(1):15793
pubmed: 29150645
Chem Rev. 2013 Nov 13;113(11):8523-45
pubmed: 23731471
Semin Cell Dev Biol. 2017 Aug;68:72-84
pubmed: 28506892
J Cell Sci. 1995 Jan;108 ( Pt 1):257-63
pubmed: 7738103
Cell. 2013 Dec 5;155(6):1233-43
pubmed: 24315095
Cell Death Differ. 2012 May;19(5):798-807
pubmed: 22075984
J Struct Biol. 2007 Aug;159(2):277-89
pubmed: 17446086
Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10406-11
pubmed: 20498086
Mol Cell Proteomics. 2013 Mar;12(3):664-78
pubmed: 23242554
J Cell Biol. 1993 Jul;122(1):1-19
pubmed: 8314837
J Cell Biol. 1999 Apr 19;145(2):237-54
pubmed: 10209021
Trends Biochem Sci. 2021 Jul;46(7):595-607
pubmed: 33563541
Mol Biol Cell. 2005 Dec;16(12):5610-20
pubmed: 16195343
Nat Commun. 2015 Jun 26;6:7532
pubmed: 26112706
Wiley Interdiscip Rev RNA. 2012 Jan-Feb;3(1):13-25
pubmed: 21796793
Genetics. 2014 Aug;197(4):1213-24
pubmed: 24931410
Nat Struct Mol Biol. 2009 Mar;16(3):247-54
pubmed: 19219046
Mol Cell. 2001 Aug;8(2):397-406
pubmed: 11545741
Science. 2003 May 2;300(5620):805-8
pubmed: 12730603
J Cell Biol. 2006 May 8;173(3):361-71
pubmed: 16682526
Cell Res. 2020 Jun;30(6):532-540
pubmed: 32367042
Cell. 2016 Mar 10;164(6):1162-1171
pubmed: 26967283
Mol Cell Biol. 2001 Apr;21(7):2545-54
pubmed: 11259602
J Cell Biol. 2002 Feb 18;156(4):617-30
pubmed: 11839768
Nature. 2017 Oct 12;550(7675):280-284
pubmed: 28976959
Science. 2016 Apr 15;352(6283):aaf1015
pubmed: 27081075
PLoS One. 2014 Apr 10;9(4):e93709
pubmed: 24722547
Mol Cell Biol. 2004 Feb;24(3):1155-67
pubmed: 14729961
Traffic. 2019 Nov;20(11):829-840
pubmed: 31513326
J Phys Chem B. 2019 Jun 20;123(24):5107-5120
pubmed: 31117612
EMBO J. 2002 Feb 1;21(3):387-97
pubmed: 11823431
Exp Cell Res. 2010 Apr 1;316(6):1028-38
pubmed: 19853599
Annu Rev Biochem. 2011;80:613-43
pubmed: 21495847
J Biol Chem. 2001 Jun 8;276(23):20536-43
pubmed: 11259411
Science. 2021 Dec 10;374(6573):eabd9776
pubmed: 34762489
Cell. 2009 Feb 20;136(4):688-700
pubmed: 19239889
J Cell Biol. 2021 Apr 5;220(4):
pubmed: 33570570
J Cell Biol. 2000 Feb 21;148(4):635-51
pubmed: 10684247
J Struct Biol. 2002 Oct-Dec;140(1-3):254-67
pubmed: 12490173
FEBS J. 2015 Feb;282(3):445-62
pubmed: 25429850
EMBO J. 2011 Aug 31;30(17):3457-74
pubmed: 21878989
Mol Biol Cell. 2005 Sep;16(9):4304-15
pubmed: 16000379
Mol Cell. 1998 Apr;1(5):649-59
pubmed: 9660949
Genes Dev. 2005 Jul 1;19(13):1512-7
pubmed: 15998806
Eur J Hum Genet. 2016 Oct;24(10):1388-95
pubmed: 27071718
Mol Biol Cell. 2014 Aug 15;25(16):2472-84
pubmed: 24943837
Nat Commun. 2020 Sep 11;11(1):4577
pubmed: 32917881
Immunity. 1997 May;6(5):571-82
pubmed: 9175835
J Cell Biol. 2001 May 14;153(4):745-62
pubmed: 11352936
Trends Endocrinol Metab. 2004 Jan-Feb;15(1):34-9
pubmed: 14693424
Chromosoma. 2005 Nov;114(5):319-30
pubmed: 16133350
J Biol Chem. 2002 Dec 27;277(52):50597-606
pubmed: 12372823
Genes Dev. 2015 Jun 15;29(12):1224-38
pubmed: 26080816
Adv Exp Med Biol. 2019;1203:33-81
pubmed: 31811630
Nat Cell Biol. 2001 Jan;3(1):97-9
pubmed: 11146633
J Cell Biol. 2000 Nov 27;151(5):1057-66
pubmed: 11086007
Eukaryot Cell. 2007 Sep;6(9):1521-7
pubmed: 17660363
J Cell Biol. 2000 Oct 2;151(1):1-14
pubmed: 11018049
Mol Biol Cell. 1999 Mar;10(3):649-64
pubmed: 10069809
J Cell Biol. 1993 Nov;123(4):771-83
pubmed: 8227139
Nat Struct Mol Biol. 2015 Oct;22(10):774-81
pubmed: 26344569
J Cell Physiol. 2013 Nov;228(11):2222-31
pubmed: 23625794
Genes (Basel). 2015 Mar 20;6(1):124-49
pubmed: 25802992
Cell. 2007 Aug 10;130(3):512-23
pubmed: 17693259
J Mol Biol. 2003 Feb 21;326(3):849-58
pubmed: 12581645
Mol Cell Biol. 2000 Aug;20(15):5619-30
pubmed: 10891499
Structure. 2012 Jun 6;20(6):998-1006
pubmed: 22632834
Nat Struct Mol Biol. 2016 Mar;23(3):239-47
pubmed: 26878241
Mol Biol Cell. 2013 Apr;24(8):1222-31
pubmed: 23427268
J Cell Sci. 2009 Jun 15;122(Pt 12):1933-7
pubmed: 19494120
Elife. 2015 Jan 06;4:
pubmed: 25562883
Curr Biol. 1999 Jun 3;9(11):569-78
pubmed: 10359695
Dev Cell. 2015 Jun 22;33(6):717-28
pubmed: 26051542
Mol Biol Cell. 2015 Apr 1;26(7):1386-94
pubmed: 25631821
J Cell Biol. 2003 Aug 4;162(3):391-401
pubmed: 12885761
J Cell Biol. 2007 Sep 24;178(7):1121-32
pubmed: 17875746
J Cell Biol. 1982 Apr;93(1):63-75
pubmed: 7068761
J Biol Chem. 1995 Jun 9;270(23):14209-13
pubmed: 7775481
Science. 2015 Oct 2;350(6256):106-10
pubmed: 26292704
PLoS Genet. 2021 Nov 18;17(11):e1009899
pubmed: 34793452
Mol Cell. 2007 Dec 14;28(5):850-9
pubmed: 18082609
Mol Cell. 2006 Apr 7;22(1):93-103
pubmed: 16600873
J Cell Sci. 2017 Jul 15;130(14):2306-2316
pubmed: 28576968
EMBO J. 1999 Jul 1;18(13):3746-56
pubmed: 10393189
Nat Struct Mol Biol. 2009 Nov;16(11):1173-7
pubmed: 19855394
Cell. 2012 Jun 8;149(6):1393-406
pubmed: 22658674
Nature. 2011 May 19;473(7347):337-42
pubmed: 21593866
Curr Opin Cell Biol. 2004 Jun;16(3):272-8
pubmed: 15145351
Cell. 2002 Feb 22;108(4):501-12
pubmed: 11909521
Biophys J. 2014 Apr 15;106(8):1751-62
pubmed: 24739174
Cell. 2016 Nov 17;167(5):1215-1228.e25
pubmed: 27839866
J Biol Chem. 2001 Nov 30;276(48):44953-62
pubmed: 11579093
RNA. 2017 Jun;23(6):927-937
pubmed: 28325843
J Mol Biol. 2003 Apr 18;328(1):119-30
pubmed: 12684002
Genomics Proteomics Bioinformatics. 2019 Apr;17(2):119-128
pubmed: 30710789
J Cell Sci. 2017 Oct 1;130(19):3347-3359
pubmed: 28751496
EMBO J. 1999 May 4;18(9):2593-609
pubmed: 10228171
Curr Opin Cell Biol. 2004 Jun;16(3):314-21
pubmed: 15145357
EMBO J. 2001 May 15;20(10):2587-95
pubmed: 11350948
Nature. 2018 Mar 22;555(7697):475-482
pubmed: 29539637
Cancers (Basel). 2020 Dec 25;13(1):
pubmed: 33375634
Nucleus. 2011 Sep-Oct;2(5):500-9
pubmed: 21983083
Biochem Biophys Res Commun. 2008 Sep 5;373(4):457-61
pubmed: 18489905
BMC Cell Biol. 2009 Oct 16;10:74
pubmed: 19835572
EMBO J. 1999 Oct 15;18(20):5761-77
pubmed: 10610322
EMBO J. 1996 Oct 15;15(20):5574-83
pubmed: 8896451
J Cell Sci. 2012 Jan 1;125(Pt 1):144-54
pubmed: 22250199
Nature. 2009 Feb 19;457(7232):1023-7
pubmed: 19098896
J Cell Biol. 2019 Sep 2;218(9):2962-2981
pubmed: 31375530
Genes Cells. 2002 Apr;7(4):421-34
pubmed: 11952838
Curr Biol. 2003 Jul 15;13(14):1159-68
pubmed: 12867026
Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13308-13
pubmed: 14583593
J Vis Exp. 2018 Jan 16;(131):
pubmed: 29364223
FEBS Lett. 2008 Jun 18;582(14):1987-96
pubmed: 18394429
EMBO J. 1990 May;9(5):1495-502
pubmed: 2184032
J Cell Sci. 2013 Jun 15;126(Pt 12):2656-67
pubmed: 23591820
J Mol Biol. 1996 Jul 19;260(3):304-11
pubmed: 8757794
Nat Rev Genet. 2014 Mar;15(3):163-75
pubmed: 24514444
Cell. 2000 Jul 7;102(1):99-108
pubmed: 10929717
Science. 2015 Oct 2;350(6256):56-64
pubmed: 26316600
Nat Cell Biol. 1999 Jun;1(2):E31-3
pubmed: 10559889