Structural Bases for the Involvement of Phosphatidylinositol-4,5-bisphosphate in the Internalization of the Cell-Penetrating Peptide Penetratin.

Carrier Proteins / metabolism Cell-Penetrating Peptides / metabolism Phosphatidylinositols Protein Binding

Journal

ACS chemical biology
ISSN: 1554-8937
Titre abrégé: ACS Chem Biol
Pays: United States
ID NLM: 101282906

Informations de publication

Date de publication:
17 06 2022
Historique:
pubmed: 25 5 2022
medline: 22 6 2022
entrez: 24 5 2022
Statut: ppublish

Résumé

Cell-penetrating peptides cross cell membranes through various parallel internalization pathways. Herein, we analyze the role of the negatively charged lipid phosphatidylinositol-4,5-bisphosphate (PI(4,5)P

Identifiants

DOI: 10.1021/acschembio.1c00974 PMID: 35608167
pubmed: 35608167
doi: 10.1021/acschembio.1c00974
doi:

Substances chimiques

Carrier Proteins 0
Cell-Penetrating Peptides 0
Phosphatidylinositols 0
penetratin A2AQZ20TEK

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1427-1439

Auteurs

Leïla Bechtella (L)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.

Edward Chalouhi (E)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.

Paula Milán Rodríguez (P)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.

Marine Cosset (M)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.

Delphine Ravault (D)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.

Françoise Illien (F)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.

Sandrine Sagan (S)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.

Ludovic Carlier (L)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.
ORCID: 0000-0002-9036-6561

Olivier Lequin (O)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.
ORCID: 0000-0001-5307-3068

Patrick F J Fuchs (PFJ)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.
Université de Paris, UFR Sciences du Vivant, 75013 Paris, France.
ORCID: 0000-0001-7117-994X

Emmanuelle Sachon (E)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.
Sorbonne Université, Mass Spectrometry Sciences Sorbonne Université, MS3U platform, UFR 926, UFR 927, Paris 75005, France.
ORCID: 0000-0002-2271-8924

Astrid Walrant (A)

Laboratoire des Biomolécules, LBM, Sorbonne Université, École normale supérieure, PSL University, CNRS, 75005 Paris, France.
ORCID: 0000-0003-4054-905X

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Structural Bases for the Involvement of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptides de pénétration cellulaire › Structural Bases for the Involvement of...
questionsmedicales.fr › Lipides › Lipides membranaires › Phospholipides › Glycérophosphate › Acides phosphatidiques › Glycérophospholipides › Phosphatidyl inositols › Structural Bases for the Involvement of...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Structural Bases for the Involvement of...