Evolution of transcription factor binding through sequence variations and turnover of binding sites.


Journal

Genome research
ISSN: 1549-5469
Titre abrégé: Genome Res
Pays: United States
ID NLM: 9518021

Informations de publication

Date de publication:
06 2022
Historique:
received: 28 02 2022
accepted: 20 05 2022
pubmed: 27 5 2022
medline: 29 6 2022
entrez: 26 5 2022
Statut: ppublish

Résumé

Variations in noncoding regulatory sequences play a central role in evolution. Interpreting such variations, however, remains difficult even in the context of defined attributes such as transcription factor (TF) binding sites. Here, we systematically link variations in

Identifiants

pubmed: 35618416
pii: gr.276715.122
doi: 10.1101/gr.276715.122
pmc: PMC9248875
doi:

Substances chimiques

Transcription Factors 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1099-1111

Informations de copyright

© 2022 Krieger et al.; Published by Cold Spring Harbor Laboratory Press.

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Auteurs

Gat Krieger (G)

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

Offir Lupo (O)

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

Patricia Wittkopp (P)

Department of Ecology and Evolutionary Biology, Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA.

Naama Barkai (N)

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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