Target-enrichment sequencing yields valuable genomic data for challenging-to-culture bacteria of public health importance.

Bacillus anthracis Mycoplasma amphoriforme RNA baits bacteria genomic target-enrichment sequencing

Journal

Microbial genomics
ISSN: 2057-5858
Titre abrégé: Microb Genom
Pays: England
ID NLM: 101671820

Informations de publication

Date de publication:
05 2022
Historique:
entrez: 27 5 2022
pubmed: 28 5 2022
medline: 1 6 2022
Statut: ppublish

Résumé

Genomic data contribute invaluable information to the epidemiological investigation of pathogens of public health importance. However, whole-genome sequencing (WGS) of bacteria typically relies on culture, which represents a major hurdle for generating such data for a wide range of species for which culture is challenging. In this study, we assessed the use of culture-free target-enrichment sequencing as a method for generating genomic data for two bacterial species: (1)

Identifiants

pubmed: 35622897
doi: 10.1099/mgen.0.000836
pmc: PMC9465068
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_16045
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R012075/1
Pays : United Kingdom

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Auteurs

Tristan P W Dennis (TPW)

Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Barbara K Mable (BK)

Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Brian Brunelle (B)

Daicel Arbor Biosciences, Ann Arbor, Michigan, USA.

Alison Devault (A)

Daicel Arbor Biosciences, Ann Arbor, Michigan, USA.

Ryan W Carter (RW)

Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Clare L Ling (CL)

Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Blandina T Mmbaga (BT)

Kilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

Jo E B Halliday (JEB)

Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Katarina Oravcova (K)

Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Taya L Forde (TL)

Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

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