School performance and genetic propensities for educational attainment and depression in the etiology of self-harm: a Danish population-based study.
School-performance
linkage data
mental disorders
polygenic risk scores
self-harm
Journal
Nordic journal of psychiatry
ISSN: 1502-4725
Titre abrégé: Nord J Psychiatry
Pays: England
ID NLM: 100927567
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
pmc-release:
01
02
2024
pubmed:
1
6
2022
medline:
14
2
2023
entrez:
31
5
2022
Statut:
ppublish
Résumé
Poor school performance is linked to higher risks of self-harm. The association might be explained through genetic liabilities for depression or educational attainment. We investigated the association between school performance and self-harm in a population-based sample while assessing the potential influence of polygenic risk scores (PRSs) for depression (PRS We conducted a follow-up study of individuals born 1987-98 and followed from age 18 until 2016. The total sample consisted of a case group (23,779 diagnosed with mental disorders; schizophrenia, bipolar disorder, depression, autism, and attention deficit hyperactivity disorder (ADHD) and a randomly sampled comparison group ( Individuals in the top PRS Associations between PRS
Sections du résumé
BACKGROUND
UNASSIGNED
Poor school performance is linked to higher risks of self-harm. The association might be explained through genetic liabilities for depression or educational attainment. We investigated the association between school performance and self-harm in a population-based sample while assessing the potential influence of polygenic risk scores (PRSs) for depression (PRS
METHOD
UNASSIGNED
We conducted a follow-up study of individuals born 1987-98 and followed from age 18 until 2016. The total sample consisted of a case group (23,779 diagnosed with mental disorders; schizophrenia, bipolar disorder, depression, autism, and attention deficit hyperactivity disorder (ADHD) and a randomly sampled comparison group (
RESULTS
UNASSIGNED
Individuals in the top PRS
CONCLUSION
UNASSIGNED
Associations between PRS
Identifiants
pubmed: 35635301
doi: 10.1080/08039488.2022.2078998
pmc: PMC9883111
mid: NIHMS1862234
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
179-187Subventions
Organisme : NIMH NIH HHS
ID : U01 MH094432
Pays : United States
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