Predictive Capability of Metabolic Panels for Postoperative Atrial Fibrillation in Cardiac Surgery Patients.
Cardiac surgery
Electrolyte imbalance
Metabolic panels
Postoperative atrial fibrillation
Journal
The Journal of surgical research
ISSN: 1095-8673
Titre abrégé: J Surg Res
Pays: United States
ID NLM: 0376340
Informations de publication
Date de publication:
10 2022
10 2022
Historique:
received:
01
10
2020
revised:
13
04
2022
accepted:
22
04
2022
pubmed:
1
6
2022
medline:
27
7
2022
entrez:
31
5
2022
Statut:
ppublish
Résumé
Postoperative atrial fibrillation (POAF) occurs in up to 65% of cardiac surgery patients and is associated with an increased risk for stroke and mortality. Electrolyte disturbances in sodium (Na Metabolic panels of patients with no prior history of atrial fibrillation who did (n = 763) and did not develop POAF (n = 2144) after cardiac surgery were obtained from the Carilion Clinic electronic medical record system. We initially evaluated serum Na Neither scatter nor spaghetti plots of electrolyte data revealed a significant difference between those who did and did not develop POAF. Two logistic regression models and two random forest models with POAF status as the outcome were generated using the first observation for each electrolyte and the coefficient of the linear regression, which was obtained from a linear fit of the scatter plot. The random forest model using the first observation had a sensitivity of only 12.2%, but all four models had specificities more than 97%. Neither of the two logistic regression nor two random forest models were able to effectively predict the development of POAF from plasma ionic concentrations, but the random forest models effectively classified patients who would not develop POAF.
Identifiants
pubmed: 35636203
pii: S0022-4804(22)00288-8
doi: 10.1016/j.jss.2022.04.061
pmc: PMC9764088
mid: NIHMS1854627
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
271-281Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL159097
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR003015
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL141855
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL102298
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL138003
Pays : United States
Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.
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