Preliminary XFEL data from spontaneously grown endo-1,4-β-xylanase crystals from Hypocrea virens.


Journal

Acta crystallographica. Section F, Structural biology communications
ISSN: 2053-230X
Titre abrégé: Acta Crystallogr F Struct Biol Commun
Pays: United States
ID NLM: 101620319

Informations de publication

Date de publication:
01 Jun 2022
Historique:
received: 04 03 2022
accepted: 11 05 2022
entrez: 1 6 2022
pubmed: 2 6 2022
medline: 7 6 2022
Statut: ppublish

Résumé

The enzymatic degradation of semi-cellulosic substrates has recently received immense attention. The enzyme endo-1,4-β-xylanase is essential for the complete digestion of complex and heterogeneous hemicellulose. Here, the purification, crystallization and preliminary X-ray free-electron laser (XFEL) diffraction analysis of endo-1,4-β-xylanase from the fungus Hypocrea virens (HviGH11) are reported. Codon-optimized HviGH11 was overexpressed in Escherichia coli and spontaneously crystallized after His-tag purification and concentration. Preliminary XFEL diffraction data were collected at the Pohang Accelerator Laboratory XFEL (PAL-XFEL). A total of 1021 images containing Bragg peaks were obtained and indexed. The HviGH11 crystals belonged to the orthorhombic space group P2

Identifiants

pubmed: 35647679
pii: S2053230X22005118
doi: 10.1107/S2053230X22005118
pmc: PMC9158662
doi:

Substances chimiques

Endo-1,4-beta Xylanases EC 3.2.1.8

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

226-231

Subventions

Organisme : National Research Foundation of Korea
ID : NRF-2017M3A9F6029736
Organisme : National Research Foundation of Korea
ID : NRF-2020M3H1A1075314
Organisme : National Research Foundation of Korea
ID : NRF-2021R1I1A1A01050838

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Auteurs

Ki Hyun Nam (KH)

Department of Life Science, Pohang University of Science and Technology, Pohang, Republic of Korea.

Sehan Park (S)

Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang, Republic of Korea.

Jaehyun Park (J)

Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang, Republic of Korea.

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Classifications MeSH