Arginine and glutamine supplementation on transthyretin levels in severely burned patients: A systematic review.
Arginine
Burns
Glutamine
Immunomodulators
Transthyretin
Journal
Nutrition (Burbank, Los Angeles County, Calif.)
ISSN: 1873-1244
Titre abrégé: Nutrition
Pays: United States
ID NLM: 8802712
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
received:
10
09
2021
revised:
07
03
2022
accepted:
12
03
2022
pubmed:
3
6
2022
medline:
8
7
2022
entrez:
2
6
2022
Statut:
ppublish
Résumé
The aim of this study was to investigate the influence of supplementation with the immunomodulators arginine and glutamine on transthyretin levels in burn patients. This systematic review followed the protocol proposed and registered in PROSPERO (CRD42021239526) and was carried out following the PRISMA checklist for systematic reviews. Forty-four studies were evaluated. Of the 44, we included 6 for complete analysis. In five of the six clinical trials, glutamine was the most used immunomodulator (0.5 g·kg·d In view of the content in the present review, it is possible to affirm that the supplementation of immunomodulators in burn patients is an effective strategy for their treatment, and that the adequate nutritional offer may be a predictor of a favorable outcome. However, regarding the increase in transthyretin values, this finding needs to be considered with reservations as the values can be altered by the inflammatory activity, and not necessarily related to the use of a supplement.
Identifiants
pubmed: 35653933
pii: S0899-9007(22)00070-3
doi: 10.1016/j.nut.2022.111657
pii:
doi:
Substances chimiques
Prealbumin
0
Glutamine
0RH81L854J
Arginine
94ZLA3W45F
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
111657Informations de copyright
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