Extracorporeal membrane oxygenation as a bridge to durable mechanical circulatory support or heart transplantation.
Circulatory support
ECMO
apheresis and detoxification techniques
artificial kidney
cardiac assist and artificial heart
congestive heart failure
total artificial heart
ventricular assist devices (VAD)
Journal
The International journal of artificial organs
ISSN: 1724-6040
Titre abrégé: Int J Artif Organs
Pays: United States
ID NLM: 7802649
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
pubmed:
7
6
2022
medline:
24
6
2022
entrez:
6
6
2022
Statut:
ppublish
Résumé
Patients with cardiogenic shock may require extracorporeal membrane oxygenation (ECMO) prior to durable mechanical circulatory support (dMCS) or heart transplantation (HTx). We investigated the clinical characteristics and outcomes of adult patients with ECMO support as bridge to dMCS or HTx between 1/1/13 and 12/31/20. Of 57 patients who underwent bridging ECMO, 41 (72%) received dMCS (approximately half with biventricular support) and 16 (28%) underwent HTx, 13 (81%) after the 2018 UNOS allocation system change. ECMO → HTx patients had shorter ventilatory time (3.5 vs 7.5 days; Patients on ECMO who undergo HTx, with or without dMCS bridge, have acceptable post-HTx survival. These findings suggest that HTx from ECMO is a viable option for carefully selected patients deemed acceptable to proceed with definitive advanced therapies, especially in the era of the new UNOS allocation system.
Sections du résumé
BACKGROUND
UNASSIGNED
Patients with cardiogenic shock may require extracorporeal membrane oxygenation (ECMO) prior to durable mechanical circulatory support (dMCS) or heart transplantation (HTx).
METHODS
UNASSIGNED
We investigated the clinical characteristics and outcomes of adult patients with ECMO support as bridge to dMCS or HTx between 1/1/13 and 12/31/20.
RESULTS
UNASSIGNED
Of 57 patients who underwent bridging ECMO, 41 (72%) received dMCS (approximately half with biventricular support) and 16 (28%) underwent HTx, 13 (81%) after the 2018 UNOS allocation system change. ECMO → HTx patients had shorter ventilatory time (3.5 vs 7.5 days;
CONCLUSION
UNASSIGNED
Patients on ECMO who undergo HTx, with or without dMCS bridge, have acceptable post-HTx survival. These findings suggest that HTx from ECMO is a viable option for carefully selected patients deemed acceptable to proceed with definitive advanced therapies, especially in the era of the new UNOS allocation system.
Identifiants
pubmed: 35658592
doi: 10.1177/03913988221103284
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM