Targeting Th17 cells in HIV-1 remission/cure interventions.

CD4-Positive T-Lymphocytes HIV Infections HIV-1 Humans Th17 Cells Virus Latency
HIV-1 cure Th17 cells antiretroviral therapy metabolic pathways transcription factors viral reservoirs

Journal

Trends in immunology
ISSN: 1471-4981
Titre abrégé: Trends Immunol
Pays: England
ID NLM: 100966032

Informations de publication

Date de publication:
07 2022
Historique:
received: 06 04 2022
revised: 29 04 2022
accepted: 29 04 2022
pubmed: 7 6 2022
medline: 29 6 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

Since the discovery of HIV-1, progress has been made in deciphering the viral replication cycle and mechanisms of host-pathogen interactions that has facilitated the implementation of effective antiretroviral therapies (ARTs). Major barriers to HIV-1 remission/cure include the persistence of viral reservoirs (VRs) in long-lived CD4

Identifiants

DOI: 10.1016/j.it.2022.04.013 PMID: 35659433
pubmed: 35659433
pii: S1471-4906(22)00099-0
doi: 10.1016/j.it.2022.04.013
pii:
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

580-594

Subventions

Organisme : CIHR
ID : HB2-164064
Pays : Canada
Organisme : CIHR
ID : PJT #153052
Pays : Canada
Organisme : CIHR
ID : PJT #178127
Pays : Canada
Organisme : CIHR
ID : PJH #175380
Pays : Canada

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests No interests are declared

Auteurs

Augustine Fert (A)

Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada.

Laurence Raymond Marchand (L)

Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.

Tomas Raul Wiche Salinas (TR)

Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada.

Petronela Ancuta (P)

Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montréal, QC, Canada; Department of Microbiology and Immunology, Faculty of Biology, University of Bucharest, Bucharest, Romania; The Research Institute of the University of Bucharest, Bucharest, Romania. Electronic address: petronela.ancuta@umontreal.ca.

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Classifications MeSH

questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD4+ › Targeting Th17 cells in HIV-1 remission/cure...
questionsmedicales.fr › Maladies du système immunitaire › Déficits immunitaires › Infections à VIH › Targeting Th17 cells in HIV-1 remission/cure...
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Lentivirus › Lentivirus des primates › VIH (Virus de l'Immunodéficience Humaine) › VIH-1 (Virus de l'Immunodéficience Humaine de type 1) › Targeting Th17 cells in HIV-1 remission/cure...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Targeting Th17 cells in HIV-1 remission/cure...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T auxiliaires › Cellules Th17 › Targeting Th17 cells in HIV-1 remission/cure...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Latence virale › Targeting Th17 cells in HIV-1 remission/cure...