Phylogenetic analysis of lumpy skin disease virus isolates in Russia in 2019-2021.


Journal

Archives of virology
ISSN: 1432-8798
Titre abrégé: Arch Virol
Pays: Austria
ID NLM: 7506870

Informations de publication

Date de publication:
Aug 2022
Historique:
received: 11 03 2022
accepted: 15 04 2022
pubmed: 7 6 2022
medline: 29 6 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

Lumpy skin disease continues to pose a threat to countries in the East and Asia-Pacific regions. Although only occasional LSDV outbreaks have been reported recently in Russia, these have been mainly restricted to the Far East region of the country. An increase in the number of outbreaks in South East Asia has been attributed to recombinant vaccine-like LSDV strains. In this scenario, it is epidemiologically important to perform phylogenetic analysis to track the distribution of LSDV worldwide at the genetic level to understand routes of migration and molecular evolution patterns. In this study, we investigated the RPO30 and GPCR gene regions of LSDV isolates associated with outbreaks in 2019-2021 in Siberia and the Far East region of Russia. The inferred phylogeny confirms the recombinant origin of these sequenced isolates. Based on sequences of these selected loci, the isolates from 2019 differed from isolates detected in Russia in the past and from isolates from Asian countries, while the isolates from 2020 and 2021 exhibited a high degree of similarity to the Asian isolates. These findings indicate that recombinant LSDV strains continue to persist and additionally point to the establishment of a specific lineage of recombinant isolates in the region. Full genome sequencing is still needed to gain more information about how the circulating isolates are related to each other.

Identifiants

pubmed: 35666394
doi: 10.1007/s00705-022-05487-7
pii: 10.1007/s00705-022-05487-7
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1693-1699

Subventions

Organisme : Ministry of Education and Science of Russia
ID : 075-15-2021-1054

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.

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Auteurs

Alena Krotova (A)

Federal Center for Animal Health, Vladimir, Russia.

Ali Mazloum (A)

Federal Center for Animal Health, Vladimir, Russia.

Olga Byadovskaya (O)

Federal Center for Animal Health, Vladimir, Russia.

Alexander Sprygin (A)

Federal Center for Animal Health, Vladimir, Russia. spriginav@mail.ru.

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