Epitope Mapping of the Anti-Human CCR2 Monoclonal Antibody C

Alanine Animals Antibodies, Monoclonal Epitope Mapping Epitopes Mice Peptides Receptors, CCR2 Receptors, Chemokine / metabolism
C2Mab-9 enzyme-linked immunosorbent assay epitope flow cytometry human CCR2 monoclonal antibody

Journal

Monoclonal antibodies in immunodiagnosis and immunotherapy
ISSN: 2167-9436
Titre abrégé: Monoclon Antib Immunodiagn Immunother
Pays: United States
ID NLM: 101590955

Informations de publication

Date de publication:
Jun 2022
Historique:
pubmed: 7 6 2022
medline: 28 6 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

CC chemokine receptor type-2 (CCR2) belongs to the G protein-coupled receptors superfamily, localized on cell surface of some immune-related cells, including monocytes and macrophages. CCR2 and its ligand CCL2 are involved in the progression of various diseases such as cancers. Therefore, CCR2-targeted monoclonal antibodies (mAbs) are needed for treatment and diagnosis. Previously, we successfully developed an anti-human CCR2 (hCCR2) mAb, C

Identifiants

DOI: 10.1089/mab.2022.0012 PMID: 35666539
pubmed: 35666539
doi: 10.1089/mab.2022.0012
doi:

Substances chimiques

Antibodies, Monoclonal 0
Ccr2 protein, mouse 0
Epitopes 0
Peptides 0
Receptors, CCR2 0
Receptors, Chemokine 0
Alanine OF5P57N2ZX

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

150-156

Auteurs

Tomohiro Tanaka (T)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.

Guanjie Li (G)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Teizo Asano (T)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.

Mika K Kaneko (MK)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.

Hiroyuki Suzuki (H)

Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Yukinari Kato (Y)

Department of Antibody Drug Development and Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
ORCID: 0000-0001-5385-8201

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Alanine › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Eucaryotes › Animaux › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Cartographie d'interactions entre protéines › Cartographie épitopique › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux chimiokines › Récepteurs CCR › Récepteurs CCR2 › Epitope Mapping of the Anti-Human CCR2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux chimiokines › Epitope Mapping of the Anti-Human CCR2...