Design of New Potent and Selective Thiophene-Based K

KV1.3 anticancer drugs antiproliferative activity apoptosis potassium ion channels

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
24 May 2022
Historique:
received: 25 04 2022
revised: 16 05 2022
accepted: 17 05 2022
entrez: 10 6 2022
pubmed: 11 6 2022
medline: 11 6 2022
Statut: epublish

Résumé

The voltage-gated potassium channel K

Identifiants

pubmed: 35681571
pii: cancers14112595
doi: 10.3390/cancers14112595
pmc: PMC9179341
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Slovenian Research Agency
ID : J1-9192, N1-0098, P1-0245
Organisme : Max Planck Society
ID : No. 813834-PHIONIC-H2020-MSCA-ITN-2018.
Organisme : Research Foundation - Flanders
ID : GOE7120N, GOC2319N, and GOA4919N
Organisme : KU Leuven
ID : PDM/19/164
Organisme : Research Foundation - Flanders
ID : Vlaanderen grant 12W7822N

Commentaires et corrections

Type : ErratumIn

Références

Biochemistry. 2002 Jun 18;41(24):7781-94
pubmed: 12056910
Mol Pharmacol. 2005 Nov;68(5):1254-70
pubmed: 16099841
J Chem Inf Model. 2005 Jan-Feb;45(1):160-9
pubmed: 15667141
Physiology (Bethesda). 2004 Oct;19:285-92
pubmed: 15381757
Front Oncol. 2019 Sep 24;9:933
pubmed: 31612103
Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):
pubmed: 35091471
Biophys J. 2011 Dec 7;101(11):2652-60
pubmed: 22261053
Leukemia. 2013 Aug;27(8):1782-5
pubmed: 23426166
J Pharmacol Toxicol Methods. 2002 Sep-Oct;48(2):65-80
pubmed: 14565563
Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2477-92
pubmed: 25517985
J Pharmacol Toxicol Methods. 2004 Sep-Oct;50(2):93-101
pubmed: 15385083
Am J Physiol Cell Physiol. 2018 Jan 1;314(1):C27-C42
pubmed: 28931540
Expert Opin Ther Targets. 2018 Feb;22(2):101-105
pubmed: 29258373
J Pharmacol Toxicol Methods. 2005 Jul-Aug;52(1):146-53
pubmed: 15936218
Cancer Cell. 2017 Apr 10;31(4):516-531.e10
pubmed: 28399409
Oncotarget. 2017 Jun 13;8(24):38276-38293
pubmed: 27542263
EMBO Mol Med. 2012 Jul;4(7):577-93
pubmed: 22496117
Front Chem. 2018 Jun 19;6:229
pubmed: 29971231
PLoS One. 2008;3(12):e4009
pubmed: 19104661
Bioorg Chem. 2020 May;98:103746
pubmed: 32199306
Front Physiol. 2013 Oct 10;4:283
pubmed: 24133455
Science. 2005 Aug 5;309(5736):897-903
pubmed: 16002581
Front Cell Dev Biol. 2020 Dec 14;8:611853
pubmed: 33381507
Front Oncol. 2017 Sep 29;7:239
pubmed: 29034212
Cancers (Basel). 2019 Mar 01;11(3):
pubmed: 30823672
Cell Mol Life Sci. 2015 Oct;72(19):3677-93
pubmed: 26070303
Curr Opin Chem Biol. 2017 Jun;38:97-107
pubmed: 28412597
Mol Pharmacol. 2019 May;95(5):537-550
pubmed: 30770456
Cell Discov. 2021 Jun 1;7(1):39
pubmed: 34059645

Auteurs

Špela Gubič (Š)

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.

Louise Antonia Hendrickx (LA)

Campus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.

Xiaoyi Shi (X)

AG Oncophysiology, Max-Planck Institute for Multidisciplinary Sciences, Hermann-Rein-Str. 3, 37075 Göttingen, Germany.

Žan Toplak (Ž)

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.

Štefan Možina (Š)

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.

Kenny M Van Theemsche (KMV)

Laboratory for Molecular, Cellular and Network Excitability, Department of Biomedical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Department of Basic and Applied Medical Sciences, Ghent University, Corneel Heymanslaan 10 (Entrance 36), 9000 Ghent, Belgium.

Ernesto Lopes Pinheiro-Junior (EL)

Campus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.

Steve Peigneur (S)

Campus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.

Alain J Labro (AJ)

Laboratory for Molecular, Cellular and Network Excitability, Department of Biomedical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Department of Basic and Applied Medical Sciences, Ghent University, Corneel Heymanslaan 10 (Entrance 36), 9000 Ghent, Belgium.

Luis A Pardo (LA)

AG Oncophysiology, Max-Planck Institute for Multidisciplinary Sciences, Hermann-Rein-Str. 3, 37075 Göttingen, Germany.

Jan Tytgat (J)

Campus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.

Tihomir Tomašič (T)

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.

Lucija Peterlin Mašič (LP)

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.

Classifications MeSH