Alain J Labro

Affiliations

Department of Biomedical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.
Department of Basic Medical Sciences, University of Ghent, C. Heymanslaan 10, 9000 Ghent, Belgium.

Publications (17)

Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient.

Cardiovascular research

Avec: Szilvia Déri , János Borbás , Teodóra Hartai , Lidia Hategan , Beáta Csányi , Ádám Visnyovszki , Tamara Madácsy , József Maléth , Zoltán Hegedűs , István Nagy , Rohit Arora , Alain J Labro , László Környei , András Varró , Róbert Sepp , Balázs Ördög

Developmental Toxicity and Biotransformation of Two Anti-Epileptics in Zebrafish Embryos and Early Larvae.

International journal of molecular sciences

Avec: Chloé Bars , Jente Hoyberghs , Allan Valenzuela , Laura Buyssens , Miriam Ayuso , Chris Van Ginneken , Alain J Labro , Kenn Foubert , Steven J Van Cruchten

The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells.

Channels (Austin, Tex.)

Avec: Dieter V Van de Sande , Ivan Kopljar , Alaerts Maaike , Ard Teisman , David J Gallacher , Loeys Bart , Dirk J Snyders , Luc Leybaert , Hua Rong Lu , Alain J Labro

Morpho-functional comparison of differentiation protocols to create iPSC-derived cardiomyocytes.

Biology open

Avec: Aleksandra Nijak , Eline Simons , Bert Vandendriessche , Dieter Van de Sande , Erik Fransen , Ewa Sieliwończyk , Ilse Van Gucht , Emeline Van Craenenbroeck , Johan Saenen , Hein Heidbuchel , Peter Ponsaerts , Alain J Labro , Dirk Snyders , Winnok De Vos , Dorien Schepers , Maaike Alaerts , Bart L Loeys

The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels.

Science advances

Avec: Laura Coonen , Evelyn Martinez-Morales , Dieter V Van De Sande , Dirk J Snyders , D Marien Cortes , Luis G Cuello , Alain J Labro

Immunosuppressive effects of new thiophene-based K

European journal of medicinal chemistry

Avec: Špela Gubič , Alberto Montalbano , Cesare Sala , Andrea Becchetti , Louise Antonia Hendrickx , Kenny M Van Theemsche , Ernesto Lopes Pinheiro-Junior , Ginevra Chioccioli Altadonna , Steve Peigneur , Janez Ilaš , Alain J Labro , Luis A Pardo , Jan Tytgat , Tihomir Tomašič , Annarosa Arcangeli , Lucija Peterlin Mašič

Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based K

Cancers

Avec: Špela Gubič , Louise Antonia Hendrickx , Xiaoyi Shi , Žan Toplak , Štefan Možina , Kenny M Van Theemsche , Ernesto Lopes Pinheiro-Junior , Steve Peigneur , Alain J Labro , Luis A Pardo , Jan Tytgat , Tihomir Tomašič , Lucija Peterlin Mašič

Clinical and functional characterisation of a recurrent KCNQ1 variant in the Belgian population.

Orphanet journal of rare diseases

Avec: Ewa Sieliwonczyk , Maaike Alaerts , Eline Simons , Dirk Snyders , Aleksandra Nijak , Bert Vandendriessche , Dorien Schepers , Dogan Akdeniz , Emeline Van Craenenbroeck , Katleen Knaepen , Laura Rabaut , Hein Heidbuchel , Lut Van Laer , Johan Saenen , Alain J Labro , Bart Loeys

Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model.

Frontiers in pharmacology

Avec: Dieter V Van de Sande , Ivan Kopljar , Ard Teisman , David J Gallacher , Dirk J Snyders , Hua Rong Lu , Alain J Labro

Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Lena Möller , Glenn Regnier , Alain J Labro , Rikard Blunck , Dirk J Snyders

Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K

Frontiers in pharmacology

Avec: Kenny M Van Theemsche , Dieter V Van de Sande , Dirk J Snyders , Alain J Labro

Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-κB Signaling.

International journal of molecular sciences

Avec: Rohit Arora , Kenny M Van Theemsche , Samuel Van Remoortel , Dirk J Snyders , Alain J Labro , Jean-Pierre Timmermans

Evaluating the proarrhythmic risk of delayed-action compounds in serum free cell culture conditions; serum-starvation accelerates/amplifies the effect of probucol on the KCNQ1 + KCNE1 channel.

Journal of pharmacological and toxicological methods

Avec: Kenny M Van Theemsche , Lisse Frans , Dieter V Van de Sande , Evelyn Martinez-Morales , Dirk J Snyders , Alain J Labro

The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels.

Biophysical journal

Avec: Laura Coonen , Evy Mayeur , Nicolas De Neuter , Dirk J Snyders , Luis G Cuello , Alain J Labro

iPSC-Cardiomyocyte Models of Brugada Syndrome-Achievements, Challenges and Future Perspectives.

International journal of molecular sciences

Avec: Aleksandra Nijak , Johan Saenen , Alain J Labro , Dorien Schepers , Bart L Loeys , Maaike Alaerts

Design of New Potent and Selective Thiophene-Based K

Cancers

A Possible Explanation for the Low Penetrance of Pathogenic KCNE1 Variants in Long QT Syndrome Type 5.

Pharmaceuticals (Basel, Switzerland)

Avec: Szilvia Déri , Teodóra Hartai , László Virág , Norbert Jost , Alain J Labro , András Varró , István Baczkó , Stanley Nattel , Balázs Ördög

Réseau de co-auteurs

Dirk J Snyders 8 collaborations

Kenny M Van Theemsche 6 collaborations

Dieter V Van de Sande 4 collaborations

Aleksandra Nijak 3 collaborations

Johan Saenen 3 collaborations

Dorien Schepers 3 collaborations

Maaike Alaerts 3 collaborations

Špela Gubič 3 collaborations

Louise Antonia Hendrickx 3 collaborations

Ernesto Lopes Pinheiro-Junior 3 collaborations

Steve Peigneur 3 collaborations

Luis A Pardo 3 collaborations

Jan Tytgat 3 collaborations

Tihomir Tomašič 3 collaborations

Lucija Peterlin Mašič 3 collaborations

Szilvia Déri 2 collaborations

Teodóra Hartai 2 collaborations

Rohit Arora 2 collaborations

András Varró 2 collaborations

Balázs Ördög 2 collaborations

Ivan Kopljar 2 collaborations

Ard Teisman 2 collaborations

David J Gallacher 2 collaborations

Hua Rong Lu 2 collaborations

Eline Simons 2 collaborations

Bert Vandendriessche 2 collaborations

Emeline Van Craenenbroeck 2 collaborations

Hein Heidbuchel 2 collaborations

Dirk Snyders 2 collaborations

Bart L Loeys 2 collaborations

Laura Coonen 2 collaborations

Evelyn Martinez-Morales 2 collaborations

Luis G Cuello 2 collaborations

Xiaoyi Shi 2 collaborations

Žan Toplak 2 collaborations

Štefan Možina 2 collaborations

János Borbás 1 collaboration

Lidia Hategan 1 collaboration

Beáta Csányi 1 collaboration

Ádám Visnyovszki 1 collaboration

Tamara Madácsy 1 collaboration

József Maléth 1 collaboration

Zoltán Hegedűs 1 collaboration

István Nagy 1 collaboration

László Környei 1 collaboration

Róbert Sepp 1 collaboration

Chloé Bars 1 collaboration

Jente Hoyberghs 1 collaboration

Allan Valenzuela 1 collaboration

Laura Buyssens 1 collaboration

Miriam Ayuso 1 collaboration

Chris Van Ginneken 1 collaboration

Kenn Foubert 1 collaboration

Steven J Van Cruchten 1 collaboration

Alaerts Maaike 1 collaboration

Loeys Bart 1 collaboration

Luc Leybaert 1 collaboration

Dieter Van de Sande 1 collaboration

Erik Fransen 1 collaboration

Ewa Sieliwończyk 1 collaboration

Ilse Van Gucht 1 collaboration

Peter Ponsaerts 1 collaboration

Winnok De Vos 1 collaboration

Dieter V Van De Sande 1 collaboration

D Marien Cortes 1 collaboration

Alberto Montalbano 1 collaboration

Cesare Sala 1 collaboration

Andrea Becchetti 1 collaboration

Ginevra Chioccioli Altadonna 1 collaboration

Janez Ilaš 1 collaboration

Annarosa Arcangeli 1 collaboration

Ewa Sieliwonczyk 1 collaboration

Dogan Akdeniz 1 collaboration

Katleen Knaepen 1 collaboration

Laura Rabaut 1 collaboration

Lut Van Laer 1 collaboration

Bart Loeys 1 collaboration

Lena Möller 1 collaboration

Glenn Regnier 1 collaboration

Rikard Blunck 1 collaboration

Samuel Van Remoortel 1 collaboration

Jean-Pierre Timmermans 1 collaboration

Lisse Frans 1 collaboration

Evy Mayeur 1 collaboration

Nicolas De Neuter 1 collaboration

László Virág 1 collaboration

Norbert Jost 1 collaboration

István Baczkó 1 collaboration

Stanley Nattel 1 collaboration