Interaction between Bacteria and the Immune System for Cancer Immunotherapy: The α-GalCer Alliance.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
24 May 2022
Historique:
received: 06 05 2022
revised: 19 05 2022
accepted: 22 05 2022
entrez: 10 6 2022
pubmed: 11 6 2022
medline: 14 6 2022
Statut: epublish

Résumé

Non-conventional T cells, such as γδ T and invariant natural killer T (iNKT) cells, are emerging players in fighting cancer. Alpha-galactosylceramide (α-GalCer) is used as an exogenous ligand to activate iNKT cells. Human cells don't have a direct pathway producing α-GalCer, which, however, can be produced by bacteria. We searched the literature for bacteria strains that are able to produce α-GalCer and used available sequencing data to analyze their presence in human tumor tissues and their association with survival. The modulatory effect of antibiotics on the concentration of α-GalCer was analyzed in mice. The human gut bacteria

Identifiants

pubmed: 35682578
pii: ijms23115896
doi: 10.3390/ijms23115896
pmc: PMC9180740
pii:
doi:

Substances chimiques

Galactosylceramides 0
alpha-galactosylceramide 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

J Immunother Cancer. 2019 Jul 10;7(1):176
pubmed: 31292005
Front Immunol. 2021 Aug 13;12:707734
pubmed: 34484205
Sci Rep. 2021 Apr 14;11(1):8154
pubmed: 33854094
PLoS Biol. 2013 Jul;11(7):e1001610
pubmed: 23874157
Science. 2015 Nov 27;350(6264):1079-84
pubmed: 26541610
Mol Immunol. 2015 Dec;68(2 Pt A):94-7
pubmed: 26141240
J Immunol. 2012 Apr 15;188(8):3928-39
pubmed: 22412194
Mol Clin Oncol. 2021 May;14(5):93
pubmed: 33767862
Nature. 2012 Jun 13;486(7402):207-14
pubmed: 22699609
J Anus Rectum Colon. 2021 Jan 28;5(1):11-24
pubmed: 33537496
Br J Cancer. 2011 Mar 1;104(5):856-62
pubmed: 21285991
Clin Immunol. 2011 Aug;140(2):119-29
pubmed: 21095162
Annu Rev Immunol. 2007;25:297-336
pubmed: 17150027
J Lipid Res. 2017 Jun;58(6):1247-1258
pubmed: 28373486
Sci Rep. 2021 Jan 11;11(1):391
pubmed: 33432015
J Immunother Cancer. 2019 Nov 6;7(1):287
pubmed: 31694714
Cancer Lett. 2015 Jan 28;356(2 Pt B):579-88
pubmed: 25304368
Protein Cell. 2021 May;12(5):426-435
pubmed: 33296049
Gut. 2022 Apr;71(4):734-745
pubmed: 34006584
Cell Host Microbe. 2021 Feb 10;29(2):281-298.e5
pubmed: 33382980
Front Neurol. 2021 Feb 05;12:615593
pubmed: 33613432
Front Immunol. 2020 Aug 20;11:1819
pubmed: 32973759
Science. 2020 May 29;368(6494):973-980
pubmed: 32467386
Front Genet. 2019 Mar 15;10:213
pubmed: 30930939
Oncoimmunology. 2018 Feb 12;7(6):e1428156
pubmed: 29872551
FEBS Lett. 2018 Dec;592(23):3835-3864
pubmed: 29802621
Immunity. 2014 Oct 16;41(4):543-54
pubmed: 25367571
J Exp Clin Cancer Res. 2021 Oct 16;40(1):327
pubmed: 34656142
J Med Chem. 1995 Jun 9;38(12):2176-87
pubmed: 7783149
Immunity. 2018 Mar 20;48(3):453-473
pubmed: 29562195
Front Immunol. 2019 Mar 18;10:533
pubmed: 30936882
PLoS One. 2022 Mar 3;17(3):e0264652
pubmed: 35239725
Nat Commun. 2020 Jul 20;11(1):3644
pubmed: 32686686
Eur J Cancer. 2021 Jul;151:25-34
pubmed: 33962358
Nature. 2021 Apr;592(7852):138-143
pubmed: 33731925
J Lipid Res. 2019 Nov;60(11):1892-1904
pubmed: 31484693
Front Oncol. 2021 Jan 14;10:604531
pubmed: 33520714
J Thorac Oncol. 2019 Aug;14(8):1378-1389
pubmed: 31026576
Clin Cancer Res. 2005 Oct 15;11(20):7322-7
pubmed: 16243803
mSphere. 2018 Nov 14;3(6):
pubmed: 30429227

Auteurs

Arsenij Ustjanzew (A)

Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

Valentin Sencio (V)

Centre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, University of Lille, CHU Lille, Institut Pasteur de Lille, 59000 Lille, France.

François Trottein (F)

Centre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, University of Lille, CHU Lille, Institut Pasteur de Lille, 59000 Lille, France.

Jörg Faber (J)

Department of Pediatric Hematology/Oncology, Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

Roger Sandhoff (R)

Lipid Pathobiochemistry, German Cancer Research Center, 69120 Heidelberg, Germany.

Claudia Paret (C)

Department of Pediatric Hematology/Oncology, Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

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Classifications MeSH