Critical vitamin deficiencies in autism spectrum disorder: Reversible and irreversible outcomes.
Journal
European journal of clinical nutrition
ISSN: 1476-5640
Titre abrégé: Eur J Clin Nutr
Pays: England
ID NLM: 8804070
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
received:
04
04
2022
accepted:
24
05
2022
revised:
21
05
2022
pubmed:
11
6
2022
medline:
5
11
2022
entrez:
10
6
2022
Statut:
ppublish
Résumé
Vitamin deficiencies are an emerging concern in the management of children with autism spectrum disorder (ASD). Particular attention is required for recognizing the variable signs caused by unbalanced food intakes. We herein report two patients with multiple vitamin deficiencies who needed critical care showing different prognoses. Patient 1 with 'Shoshin' beriberi presenting with cardiac arrest had thiamine deficiency developed severe neurological sequelae despite rapid vitamin supplementation. Patient 2, who had leg pain and a limping gait, showed a rapid recovery with intravenous infusion and tube feeding after being diagnosed with scurvy. A literature search revealed several children with ASD with critically ill thiamine deficiency, but few reports documented a life-threatening condition in the form of cardiac arrest at the onset. Considering the high observation rate of food selectivity in children with ASD, early intervention is required to prevent the exacerbation of vitamin deficiencies to severe neurological disabilities.
Identifiants
pubmed: 35689090
doi: 10.1038/s41430-022-01170-x
pii: 10.1038/s41430-022-01170-x
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1618-1621Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature Limited.
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