Resistance to dicyclanil and imidacloprid in the sheep blowfly, Lucilia cuprina, in Australia.
Lucilia cuprina
blowfly
dicyclanil
flystrike
imidacloprid
resistance
Journal
Pest management science
ISSN: 1526-4998
Titre abrégé: Pest Manag Sci
Pays: England
ID NLM: 100898744
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
revised:
25
05
2022
received:
24
03
2022
accepted:
11
06
2022
pubmed:
13
6
2022
medline:
8
9
2022
entrez:
12
6
2022
Statut:
ppublish
Résumé
The sheep blowfly, Lucila cuprina, is a myiasis-causing parasite responsible for significant production losses and welfare issues for the Australian sheep industry. Control relies largely on the use of insecticides. The pyrimidine compound, dicyclanil, is the predominant control chemical, although other insecticides also are used, including imidacloprid, ivermectin, cyromazine and spinosad. We investigated in vitro resistance patterns and mechanisms in field-collected blowfly strains. The Walgett 2019 strain showed significant levels of resistance to both dicyclanil and imidacloprid, with resistance factors at the IC This study indicates that in vitro resistance to both dicyclanil and imidacloprid in this field-collected blowfly strain is likely mediated by cytochrome P450, with Cyp12d1 implicated as the enzyme responsible; however, it remains possible that another P450 also may be involved. A common resistance mechanism for the two drugs has important implications for drug rotation strategies designed to prolong the useful life of flystrike control chemicals. © 2022 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Sections du résumé
BACKGROUND
BACKGROUND
The sheep blowfly, Lucila cuprina, is a myiasis-causing parasite responsible for significant production losses and welfare issues for the Australian sheep industry. Control relies largely on the use of insecticides. The pyrimidine compound, dicyclanil, is the predominant control chemical, although other insecticides also are used, including imidacloprid, ivermectin, cyromazine and spinosad. We investigated in vitro resistance patterns and mechanisms in field-collected blowfly strains.
RESULTS
RESULTS
The Walgett 2019 strain showed significant levels of resistance to both dicyclanil and imidacloprid, with resistance factors at the IC
CONCLUSION
CONCLUSIONS
This study indicates that in vitro resistance to both dicyclanil and imidacloprid in this field-collected blowfly strain is likely mediated by cytochrome P450, with Cyp12d1 implicated as the enzyme responsible; however, it remains possible that another P450 also may be involved. A common resistance mechanism for the two drugs has important implications for drug rotation strategies designed to prolong the useful life of flystrike control chemicals. © 2022 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Identifiants
pubmed: 35690912
doi: 10.1002/ps.7037
pmc: PMC9540573
doi:
Substances chimiques
Insecticides
0
Juvenile Hormones
0
Neonicotinoids
0
Nitro Compounds
0
imidacloprid
3BN7M937V8
Cytochrome P-450 Enzyme System
9035-51-2
dicyclanil
DBC8O809S5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4195-4206Subventions
Organisme : Commonwealth Scientific and Industrial Research Organisation
Organisme : Elanco Animal Health
Informations de copyright
© 2022 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Références
Med Vet Entomol. 2010 Jun;24(2):176-81
pubmed: 20604863
Genome Biol. 2002 Jun 18;3(7):RESEARCH0034
pubmed: 12184808
Int J Parasitol Drugs Drug Resist. 2020 Dec;14:118-125
pubmed: 33035968
Science. 2002 Sep 27;297(5590):2253-6
pubmed: 12351787
Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10797-802
pubmed: 9380713
Pest Manag Sci. 2015 Jun;71(6):793-800
pubmed: 25404103
Nucleic Acids Res. 2012 Aug;40(15):e115
pubmed: 22730293
Insect Biochem Mol Biol. 2003 Jul;33(7):701-8
pubmed: 12826097
Aust Vet J. 2012 Nov;90(11):433-7
pubmed: 23106323
Gene. 2001 Jan 10;262(1-2):189-98
pubmed: 11179683
Int J Parasitol Drugs Drug Resist. 2015 Dec;5(3):201-8
pubmed: 27120067
J Econ Entomol. 1997 Feb;90(1):15-20
pubmed: 9071887
Aust Vet J. 2013 Jan-Feb;91(1-2):61-4
pubmed: 23356375
Med Chem (Los Angeles). 2018;8(3):
pubmed: 30221034
Insect Biochem Mol Biol. 2007 May;37(5):512-9
pubmed: 17456446
Pest Manag Sci. 2008 Jan;64(1):65-73
pubmed: 17912692
J Econ Entomol. 2004 Feb;97(1):112-9
pubmed: 14998134
Mol Genet Genomics. 2001 Dec;266(4):556-63
pubmed: 11810226
Int J Parasitol. 1995 Nov;25(11):1355-62
pubmed: 8635885
Insect Biochem Mol Biol. 2013 May;43(5):455-65
pubmed: 23470655
Aust Vet J. 2022 Jan;100(1-2):1-19
pubmed: 34761372
Int J Parasitol. 2014 Oct 15;44(12):879-91
pubmed: 25240442
Pest Manag Sci. 2012 Nov;68(11):1431-7
pubmed: 22945853
Bioinformatics. 2007 May 15;23(10):1289-91
pubmed: 17379693
Insect Biochem Mol Biol. 2006 Dec;36(12):934-42
pubmed: 17098168