Stiff person syndrome spectrum disorders; more than meets the eye.
Autoimmunity
GAD65
Glutamic acid decarboxylase
Stiff person spectrum disorders
Stiff person syndrome
Journal
Journal of neuroimmunology
ISSN: 1872-8421
Titre abrégé: J Neuroimmunol
Pays: Netherlands
ID NLM: 8109498
Informations de publication
Date de publication:
15 08 2022
15 08 2022
Historique:
received:
15
01
2022
revised:
21
05
2022
accepted:
07
06
2022
pubmed:
20
6
2022
medline:
8
7
2022
entrez:
19
6
2022
Statut:
ppublish
Résumé
Stiff person syndrome spectrum disorders (SPSD) are a group of rare neuroimmunological disorders that often include painful spasms and rigidity. However, patients have highly heterogeneous signs and symptoms which may reflect different mechanistic disease processes. Understanding subsets of patients based on clinical phenotype may be important for prognosis and guiding treatment. The goal of this review is to provide updates on SPSD and its expanding clinical spectrum, prognostic markers, and treatment considerations. Further, we describe the current understanding in immunopathogenesis and highlight gaps in our knowledge appropriate for future research directions. Examples of revised diagnostic criteria for SPSD based on phenotype are also presented.
Identifiants
pubmed: 35717735
pii: S0165-5728(22)00110-2
doi: 10.1016/j.jneuroim.2022.577915
pmc: PMC9274902
mid: NIHMS1817271
pii:
doi:
Substances chimiques
Autoantibodies
0
Glutamate Decarboxylase
EC 4.1.1.15
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
577915Subventions
Organisme : Intramural NIH HHS
ID : Z99 NS999999
Pays : United States
Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.
Références
Bone Marrow Transplant. 2020 Feb;55(2):283-306
pubmed: 31558790
Front Mol Neurosci. 2019 Jul 03;12:168
pubmed: 31333413
Nat Immunol. 2002 Feb;3(2):169-74
pubmed: 11812994
Front Immunol. 2021 Sep 03;12:723349
pubmed: 34539659
Science. 2014 Jan 10;343(6167):152-7
pubmed: 24310608
Intern Med. 2001 Sep;40(9):968-71
pubmed: 11579968
J Immunol. 2017 Dec 1;199(11):3748-3756
pubmed: 29061767
Medicine (Baltimore). 2021 Mar 26;100(12):e25260
pubmed: 33761724
Arch Neurol. 1999 Feb;56(2):172-7
pubmed: 10025422
J Neurol Neurosurg Psychiatry. 2004 Aug;75(8):1135-40
pubmed: 15258215
Front Neurol. 2022 May 27;13:865462
pubmed: 35693022
Brain. 2014 Aug;137(Pt 8):2178-92
pubmed: 24951641
J Neuroimmunol. 2020 Apr 15;341:577192
pubmed: 32087460
Neurol Neuroimmunol Neuroinflamm. 2020 Mar 2;7(3):
pubmed: 32123047
Neurology. 1994 Nov;44(11):2209-10
pubmed: 7969992
Neurologist. 2004 May;10(3):131-7
pubmed: 15140273
FEBS J. 2022 Apr;289(8):2318-2336
pubmed: 33844440
Ann Neurol. 2017 Aug;82(2):271-277
pubmed: 28749549
Ann Neurol. 2020 Sep;88(3):544-561
pubmed: 32588476
Brain. 2008 Oct;131(Pt 10):2553-63
pubmed: 18687732
Semin Immunol. 2011 Apr;23(2):67-83
pubmed: 21288738
Neuron. 2002 Feb 28;33(5):789-804
pubmed: 11879655
PLoS One. 2010 May 26;5(5):e10838
pubmed: 20520773
Neurology. 2017 Apr 4;88(14):1340-1348
pubmed: 28258082
Neurology. 2020 May 19;94(20):e2126-e2131
pubmed: 31924684
Front Neurosci. 2020 Jun 30;14:660
pubmed: 32714136
N Engl J Med. 2001 Dec 27;345(26):1870-6
pubmed: 11756577
Front Mol Neurosci. 2018 Sep 12;11:317
pubmed: 30258351
Neurol Neuroimmunol Neuroinflamm. 2016 Aug 29;3(5):e281
pubmed: 27606356
Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):18060-18067
pubmed: 31427534
Neurology. 2002 Dec 24;59(12):1985-7
pubmed: 12499499
BMC Neurol. 2019 Jan 3;19(1):1
pubmed: 30606131
J Neurol. 2021 Jan;268(1):265-275
pubmed: 32785838
Neurology. 2008 Dec 9;71(24):1955-8
pubmed: 18971449
Neurology. 2021 Feb 9;96(6):e817-e830
pubmed: 33318163
JAMA Neurol. 2016 Jun 1;73(6):714-20
pubmed: 27065452
Neurology. 2015 Jan 27;84(4):430-2
pubmed: 25520315
Curr Opin Neurol. 2017 Jun;30(3):310-316
pubmed: 28306573
J Neuroophthalmol. 2021 Dec 1;41(4):e665-e671
pubmed: 33105411
Proc Staff Meet Mayo Clin. 1963 May 22;38:203-12
pubmed: 13955116
Ann Neurol. 2013 Jan;73(1):120-8
pubmed: 23225603
Dev Neurobiol. 2011 Jan 1;71(1):45-61
pubmed: 21154909
J Neurol Neurosurg Psychiatry. 2021 Feb 9;:
pubmed: 33563803
J Neurosci. 2014 Jun 11;34(24):8151-63
pubmed: 24920620
Front Immunol. 2018 Nov 20;9:2696
pubmed: 30515171
Arthritis Rheumatol. 2020 Aug;72(8):1375-1384
pubmed: 32162841
Neuron. 2003 Feb 6;37(3):449-61
pubmed: 12575952
Neurology. 2006 Sep 26;67(6):1068-70
pubmed: 17000981
Science. 2004 Mar 5;303(5663):1532-5
pubmed: 15001782
J Hum Genet. 2015 Nov;60(11):697-702
pubmed: 26290149
Neuroscientist. 2019 Aug;25(4):344-358
pubmed: 30317911
J Neurol Sci. 2017 Jan 15;372:297-299
pubmed: 28017232
Neurology. 2014 Apr 29;82(17):1521-8
pubmed: 24696508
J Proteome Res. 2017 Jan 6;16(1):355-365
pubmed: 27700100
J Exp Med. 1993 Dec 1;178(6):2219-23
pubmed: 8245793
Neurology. 2016 Nov 29;87(22):e264-e268
pubmed: 27895250
Annu Rev Immunol. 1993;11:729-66
pubmed: 7682817
J Neuroimmunol. 2008 Sep 15;201-202:163-5
pubmed: 18639938
PLoS One. 2015 Mar 16;10(3):e0121364
pubmed: 25774787
Arch Neurol. 2004 Jun;61(6):902-4
pubmed: 15210528
JAMA Neurol. 2013 Dec;70(12):1531-6
pubmed: 24100349
Neurol Neuroimmunol Neuroinflamm. 2018 Jan 23;5(2):e438
pubmed: 29464188
Case Reports Immunol. 2020 Feb 8;2020:8454532
pubmed: 32089910
J Neurol Sci. 2020 Jun 15;413:116860
pubmed: 32388243
J Neurosci. 2007 Jun 20;27(25):6655-63
pubmed: 17581952
Transfusion. 2014 Jul;54(7):1851-6
pubmed: 24527774
Mayo Clin Proc. 1964 Feb;39:131-44
pubmed: 14117273
Lancet Neurol. 2014 Mar;13(3):276-86
pubmed: 24462240
Brain. 2016 Feb;139(Pt 2):365-79
pubmed: 26582558
Pract Neurol. 2011 Oct;11(5):272-82
pubmed: 21921002
Nat Rev Immunol. 2017 Mar;17(3):179-194
pubmed: 28138136
Hum Mol Genet. 1997 Aug;6(8):1275-82
pubmed: 9259273
BMJ Case Rep. 2020 Sep 17;13(9):
pubmed: 32943444
Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):331-5
pubmed: 8552632
Neurology. 2015 Sep 8;85(10):890-7
pubmed: 26291285
Biol Blood Marrow Transplant. 2015 Dec;21(12):2061-2068
pubmed: 26327628
JAMA. 2019 Jan 15;321(2):175-187
pubmed: 30644981
J Neurol Neurosurg Psychiatry. 1984 Mar;47(3):280-7
pubmed: 6707674
Neurology. 2000 Nov 28;55(10):1531-5
pubmed: 11094109
Neurology. 2008 Oct 14;71(16):1291-2
pubmed: 18852446
Neuropathol Appl Neurobiol. 2021 Feb;47(2):316-327
pubmed: 32910464
Clin Neurol Neurosurg. 2009 Oct;111(8):708-12
pubmed: 19616370
Neurology. 2004 Mar 9;62(5):778-82
pubmed: 15007130
Ann N Y Acad Sci. 2005 Jun;1050:1-9
pubmed: 16014515
Clin Neuropathol. 1997 Jul-Aug;16(4):214-9
pubmed: 9266148
J Clin Endocrinol Metab. 1993 Dec;77(6):1550-3
pubmed: 8263140
Front Cell Neurosci. 2012 May 15;6:23
pubmed: 22615685
Neuron. 2000 May;26(2):307-12
pubmed: 10839351
Proc Staff Meet Mayo Clin. 1956 Jul 25;31(15):421-7
pubmed: 13350379
Pediatr Neurol. 2021 Jan;114:11-15
pubmed: 33189024
Drugs Future. 2011 Nov;36(11):847
pubmed: 22869930
Brain. 2010 Nov;133(11):3166-80
pubmed: 20884644
Clin Transplant. 2020 Jun;34(6):e13875
pubmed: 32279341
JAMA Neurol. 2013 Sep 1;70(9):1140-9
pubmed: 23877118
J Physiol. 2005 Nov 15;569(Pt 1):41-57
pubmed: 16141270
Nat Med. 2006 Feb;12(2):198-206
pubmed: 16444264
Arch Neurol. 2012 Feb;69(2):230-8
pubmed: 22332190
Brain. 2006 Dec;129(Pt 12):3270-6
pubmed: 16984900
Transfus Apher Sci. 2019 Jun;58(3):310-312
pubmed: 30952585
Biol Mood Anxiety Disord. 2012 Mar 02;2:5
pubmed: 22738428
J Exp Med. 1995 Jun 1;181(6):1945-8
pubmed: 7539032
JAMA Neurol. 2014 Oct;71(10):1296-9
pubmed: 25155372
Diabetes. 2000 Oct;49(10):1621-6
pubmed: 11016444