Searching for novel antimicrobial agents among hydrazide-hydrazones of 4-iodosalicylic acid.
4-iodosalicylic acid derivatives
Antimicrobial activity screening
Hydrazide-hydrazones
Spectral analysis
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
ISSN: 1950-6007
Titre abrégé: Biomed Pharmacother
Pays: France
ID NLM: 8213295
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
21
04
2022
revised:
09
06
2022
accepted:
13
06
2022
pubmed:
21
6
2022
medline:
9
9
2022
entrez:
20
6
2022
Statut:
ppublish
Résumé
Searching for novel antimicrobial agents is up to day topic for many group of researchers due to the fact that each year the number of bacterial strains resistant to currently used medicines increases. Special attention in the scientific literature among various groups of bioactive organic compounds is focused on the antimicrobial activity of hydrazide-hydrazones. Due to this fact presented study is focused on the design, synthesis and in vitro antimicrobial properties of novel hydrazide-hydrazones of 4-iodosalicylic acid. Target compounds were synthesized by the condensation reaction of the hydrazide of 4-iodosalicylic acid with substituted (hetero)aromatic aldehydes. Chemical structure of obtained molecules was confirmed by spectral methods (
Identifiants
pubmed: 35724512
pii: S0753-3322(22)00691-6
doi: 10.1016/j.biopha.2022.113302
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Anti-Infective Agents
0
Antifungal Agents
0
Hydrazines
0
Hydrazones
0
Iodobenzoates
0
4-iodosalicylic acid
16870-28-3
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113302Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Masson SAS.. All rights reserved.