Evaluating the Efficacy of the Drinks:Ration Mobile App to Reduce Alcohol Consumption in a Help-Seeking Military Veteran Population: Randomized Controlled Trial.
alcohol consumption
alcohol intervention
alcohol misuse
digital health
digital intervention
health intervention
mHealth
mental health
military
mobile health
smartphone
smartphone application
veteran
Journal
JMIR mHealth and uHealth
ISSN: 2291-5222
Titre abrégé: JMIR Mhealth Uhealth
Pays: Canada
ID NLM: 101624439
Informations de publication
Date de publication:
20 06 2022
20 06 2022
Historique:
received:
25
04
2022
accepted:
19
05
2022
revised:
12
05
2022
entrez:
20
6
2022
pubmed:
21
6
2022
medline:
23
6
2022
Statut:
epublish
Résumé
Alcohol misuse is higher in the UK armed forces (AF) than in the general population. Research demonstrates that alcohol misuse persists after an individual leaves service, and this is notably the case for those who are seeking help for a mental health difficulty. Despite this, there is no work on testing a mobile alcohol reduction intervention that is personalized to support the UK AF. To address this gap, we investigated the efficacy of a 28-day brief alcohol intervention delivered via a mobile app in reducing weekly self-reported alcohol consumption among UK veterans seeking help for mental health difficulties. We performed a 2-arm participant-blinded randomized controlled trial (RCT). We compared a mobile app that included interactive features designed to enhance participants' motivation and personalized messaging (intervention arm) with a version that provided government guidance on alcohol consumption only (control arm). Adults were eligible if they had served in the UK AF, were currently receiving or had received clinical support for mental health symptoms, and consumed 14 units (approximately 112 g of ethanol) or more of alcohol per week. Participants received the intervention or the control mobile app (1:1 ratio). The primary outcome was a change in self-reported weekly alcohol consumption between baseline and day 84 assessed using the validated Timeline Follow Back for Alcohol Consumption (TLFB) (prior 7 days), with a secondary outcome exploring self-reported change in the Alcohol Use Disorder Identification Test (AUDIT) score. Between October 2020 and April 2021, 2708 individuals were invited to take part, of which 2531 (93.5%) did not respond, 54 (2%) were ineligible, and 123 (4.5%) responded and were randomly allocated (62, 50.4%, intervention; 61, 49.6%, control). At day 84, 41 (66.1%) participants in the intervention arm and 37 (60.7%) in the control arm completed the primary outcome assessment. Between baseline and day 84, weekly alcohol consumption reduced by -10.5 (95% CI -19.5 to -1.5) units in the control arm and -28.2 (95% CI -36.9 to -19.5) units in the intervention arm (P=.003, Cohen d=0.35). We also found a significant reduction in the AUDIT score of -3.9 (95% CI -6.2 to -1.6) in the intervention arm (Cohen d=0.48). Our primary and secondary effects did not persist over the longer term (day 168). Two adverse events were detected during the trial. This study examined the efficacy of a fully automated 28-day brief alcohol intervention delivered via a mobile app in a help-seeking sample of UK veterans with hazardous alcohol consumption. We found that participants receiving Drinks:Ration reduced their alcohol consumption more than participants receiving guidance only (at day 84). In the short term, we found Drinks:Ration is efficacious in reducing alcohol consumption in help-seeking veterans. ClinicalTrials.gov NCT04494594; https://tinyurl.com/34em6n9f. RR2-10.2196/19720.
Sections du résumé
BACKGROUND
Alcohol misuse is higher in the UK armed forces (AF) than in the general population. Research demonstrates that alcohol misuse persists after an individual leaves service, and this is notably the case for those who are seeking help for a mental health difficulty. Despite this, there is no work on testing a mobile alcohol reduction intervention that is personalized to support the UK AF.
OBJECTIVE
To address this gap, we investigated the efficacy of a 28-day brief alcohol intervention delivered via a mobile app in reducing weekly self-reported alcohol consumption among UK veterans seeking help for mental health difficulties.
METHODS
We performed a 2-arm participant-blinded randomized controlled trial (RCT). We compared a mobile app that included interactive features designed to enhance participants' motivation and personalized messaging (intervention arm) with a version that provided government guidance on alcohol consumption only (control arm). Adults were eligible if they had served in the UK AF, were currently receiving or had received clinical support for mental health symptoms, and consumed 14 units (approximately 112 g of ethanol) or more of alcohol per week. Participants received the intervention or the control mobile app (1:1 ratio). The primary outcome was a change in self-reported weekly alcohol consumption between baseline and day 84 assessed using the validated Timeline Follow Back for Alcohol Consumption (TLFB) (prior 7 days), with a secondary outcome exploring self-reported change in the Alcohol Use Disorder Identification Test (AUDIT) score.
RESULTS
Between October 2020 and April 2021, 2708 individuals were invited to take part, of which 2531 (93.5%) did not respond, 54 (2%) were ineligible, and 123 (4.5%) responded and were randomly allocated (62, 50.4%, intervention; 61, 49.6%, control). At day 84, 41 (66.1%) participants in the intervention arm and 37 (60.7%) in the control arm completed the primary outcome assessment. Between baseline and day 84, weekly alcohol consumption reduced by -10.5 (95% CI -19.5 to -1.5) units in the control arm and -28.2 (95% CI -36.9 to -19.5) units in the intervention arm (P=.003, Cohen d=0.35). We also found a significant reduction in the AUDIT score of -3.9 (95% CI -6.2 to -1.6) in the intervention arm (Cohen d=0.48). Our primary and secondary effects did not persist over the longer term (day 168). Two adverse events were detected during the trial.
CONCLUSIONS
This study examined the efficacy of a fully automated 28-day brief alcohol intervention delivered via a mobile app in a help-seeking sample of UK veterans with hazardous alcohol consumption. We found that participants receiving Drinks:Ration reduced their alcohol consumption more than participants receiving guidance only (at day 84). In the short term, we found Drinks:Ration is efficacious in reducing alcohol consumption in help-seeking veterans.
TRIAL REGISTRATION
ClinicalTrials.gov NCT04494594; https://tinyurl.com/34em6n9f.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID)
RR2-10.2196/19720.
Identifiants
pubmed: 35724966
pii: v10i6e38991
doi: 10.2196/38991
pmc: PMC9254042
doi:
Banques de données
ClinicalTrials.gov
['NCT04494594']
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e38991Subventions
Organisme : Medical Research Council
ID : MR/N028244/2
Pays : United Kingdom
Informations de copyright
©Daniel Leightley, Charlotte Williamson, Roberto J Rona, Ewan Carr, James Shearer, Jordan P Davis, Amos Simms, Nicola T Fear, Laura Goodwin, Dominic Murphy. Originally published in JMIR mHealth and uHealth (https://mhealth.jmir.org), 20.06.2022.
Références
Addiction. 1993 Jun;88(6):791-804
pubmed: 8329970
J Ment Health. 2019 Dec;28(6):654-661
pubmed: 28982279
Psychiatr Serv. 2014 Jan 1;65(1):98-105
pubmed: 24037454
Telemed J E Health. 2022 May 11;:
pubmed: 35544055
BMJ Open. 2021 Aug 27;11(8):e049815
pubmed: 34452965
PLoS One. 2014 Jun 17;9(6):e99912
pubmed: 24937483
Addict Behav. 2019 May;92:14-19
pubmed: 30572207
J Stud Alcohol. 2004 May;65(3):363-70
pubmed: 15222593
Subst Abus. 2022;43(1):1231-1244
pubmed: 35670777
JAMA. 2001 Apr 18;285(15):2006-7
pubmed: 11308440
JMIR Mhealth Uhealth. 2019 Apr 11;7(4):e11500
pubmed: 30973342
Br J Psychiatry. 2018 Dec;213(6):690-697
pubmed: 30295216
JMIR Mhealth Uhealth. 2018 Sep 11;6(9):e10074
pubmed: 30206054
Drug Alcohol Depend. 2017 Sep 1;178:571-578
pubmed: 28750345
BMJ. 2014 Mar 07;348:g1687
pubmed: 24609605
JMIR Mhealth Uhealth. 2019 May 24;7(5):e12267
pubmed: 31127726
Cochrane Database Syst Rev. 2017 Sep 25;9:CD011479
pubmed: 28944453
BMC Public Health. 2016 Jul 08;16:536
pubmed: 27392430
JMIR Res Protoc. 2020 Oct 2;9(10):e19720
pubmed: 33006569
Int Rev Psychiatry. 2011 Apr;23(2):166-72
pubmed: 21521086
Behav Res Ther. 1979;17(2):157-60
pubmed: 426744
Acta Psychiatr Scand. 2018 Dec;138(6):536-546
pubmed: 30178492
Addict Behav. 2017 Dec;75:130-137
pubmed: 28734152
Addiction. 2012 Aug;107(8):1431-40
pubmed: 22340523
Drug Alcohol Depend. 2010 Apr 1;108(1-2):37-42
pubmed: 20047802
Ann Fam Med. 2010 Jul-Aug;8(4):348-53
pubmed: 20644190
Ann Intern Med. 2007 Mar 6;146(5):317-25
pubmed: 17339617
Addict Behav. 2016 Nov;62:25-34
pubmed: 27310031
J Med Internet Res. 2011 Dec 31;13(4):e126
pubmed: 22209829
J Open Res Softw. 2018 Mar 23;6:13
pubmed: 29795769
Psychiatr Serv. 2013 Feb 1;64(2):134-41
pubmed: 23475498
Addict Sci Clin Pract. 2020 May 7;15(1):17
pubmed: 32381062