MATERNAL GUT MICROBIOTA IN PREGNANCIES RESULTING IN DOWN SYNDROME NEWBORNS - A PILOT STUDY.
Brain
Down syndrome
Microbiota
Outcome
Pregnancy
Screening
Journal
Acta clinica Croatica
ISSN: 1333-9451
Titre abrégé: Acta Clin Croat
Pays: Croatia
ID NLM: 9425483
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
07
12
2020
accepted:
17
11
2021
entrez:
23
6
2022
pubmed:
24
6
2022
medline:
25
6
2022
Statut:
ppublish
Résumé
Down syndrome (DS) is one of the main genetic abnormalities of newborns. Therefore, prenatal diagnosis of this syndrome is of paramount importance to the family and the community. The microbiota system is important in early brain development. We tried to study and compare gut microbiota (GM) composition in pregnancies that resulted in DS neonates with pregnancies that resulted in healthy children. The study population consisted of 21 pregnant women having delivered DS newborns (group 1) and 22 pregnant women who had given birth to healthy newborns (group 2). The GM composition was determined and compared between the two groups. There were no significant age and gestational age differences between the two groups (p>0.005 both). Regarding GM analysis, microorganisms of the families
Identifiants
pubmed: 35734495
doi: 10.20471/acc.2021.60.04.20
pii: acc-60-722
pmc: PMC9196220
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
722-730Références
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