Ferulic Acid, Pterostilbene, and Tyrosol Protect the Heart from ER-Stress-Induced Injury by Activating SIRT1-Dependent Deacetylation of eIF2α.
UPR
apoptosis
cardioprotection
phenolic compounds
sirtuin 1
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
14 Jun 2022
14 Jun 2022
Historique:
received:
27
04
2022
revised:
09
06
2022
accepted:
10
06
2022
entrez:
24
6
2022
pubmed:
25
6
2022
medline:
28
6
2022
Statut:
epublish
Résumé
Disturbances in Endoplasmic Reticulum (ER) homeostasis induce ER stress, which has been involved in the development and progression of various heart diseases, including arrhythmias, cardiac hypertrophy, ischemic heart diseases, dilated cardiomyopathy, and heart failure. A mild-to-moderate ER stress is considered beneficial and adaptative for heart functioning by engaging the pro-survival unfolded protein response (UPR) to restore normal ER function. By contrast, a severe or prolonged ER stress is detrimental by promoting cardiomyocyte apoptosis through hyperactivation of the UPR pathways. Previously, we have demonstrated that the NAD
Identifiants
pubmed: 35743074
pii: ijms23126628
doi: 10.3390/ijms23126628
pmc: PMC9224298
pii:
doi:
Substances chimiques
Coumaric Acids
0
Eukaryotic Initiation Factor-2
0
Stilbenes
0
4-hydroxyphenylethanol
1AK4MU3SNX
pterostilbene
26R60S6A5I
ferulic acid
AVM951ZWST
eIF-2 Kinase
EC 2.7.11.1
Sirt1 protein, mouse
EC 3.5.1.-
Sirtuin 1
EC 3.5.1.-
Phenylethyl Alcohol
ML9LGA7468
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : LabEx LERMIT
ID : ANR-10-LABX-33
Organisme : Fondation pour la Recherche Médicale
ID : DPM20121125546
Organisme : Fondation pour la Recherche Médicale
ID : FDT202001010787
Références
FEBS J. 2019 Jan;286(2):241-278
pubmed: 30027602
Circ Res. 2006 May 12;98(9):1186-93
pubmed: 16601230
Pharmacol Ther. 2018 Aug;188:140-154
pubmed: 29577959
Curr Atheroscler Rep. 2013 May;15(5):324
pubmed: 23512608
Nutr Res Pract. 2017 Oct;11(5):430-434
pubmed: 28989580
J Med Food. 2017 May;20(5):427-438
pubmed: 28387565
Molecules. 2020 Jul 20;25(14):
pubmed: 32698385
Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1375-89
pubmed: 26232232
Free Radic Biol Med. 2018 Jul;122:161-170
pubmed: 29548794
Mol Nutr Food Res. 2010 Jan;54(1):7-16
pubmed: 20013887
Circulation. 2010 Jul 27;122(4):361-9
pubmed: 20625112
J Mol Cell Cardiol. 2010 Jun;48(6):1105-10
pubmed: 19913545
Cell Death Differ. 2017 Feb;24(2):343-356
pubmed: 27911441
J Nutr. 2011 May;141(5):989S-1009S
pubmed: 21451125
Mol Nutr Food Res. 2009 May;53 Suppl 1:S7-15
pubmed: 19194969
Food Funct. 2018 Dec 13;9(12):6129-6145
pubmed: 30460963
Arch Biochem Biophys. 2010 Sep 1;501(1):79-90
pubmed: 20450879
Front Nutr. 2019 Aug 07;6:121
pubmed: 31448280
Nature. 2003 Sep 11;425(6954):191-6
pubmed: 12939617
Cells. 2020 Feb 12;9(2):
pubmed: 32059483
World J Cardiol. 2019 Jun 26;11(6):159-170
pubmed: 31367278
J Toxicol. 2013;2013:463595
pubmed: 23431291
Br J Pharmacol. 2018 Apr;175(8):1293-1304
pubmed: 28548229
Int J Mol Sci. 2019 Feb 19;20(4):
pubmed: 30791450
Cardiovasc Res. 2008 Sep 1;79(4):600-10
pubmed: 18508854
Cardiovasc Res. 2019 Feb 1;115(2):328-342
pubmed: 30084984
Toxicol Appl Pharmacol. 2019 Jan 15;363:34-46
pubmed: 30336174
Molecules. 2021 Feb 03;26(4):
pubmed: 33546142
Int J Mol Med. 2015 Sep;36(3):873-80
pubmed: 26202177
RSC Adv. 2020 Apr 27;10(28):16593-16606
pubmed: 35498835
Free Radic Biol Med. 2010 Sep 15;49(6):963-75
pubmed: 20542108
Molecules. 2019 May 24;24(10):
pubmed: 31137753
Food Chem (Oxf). 2021 Dec 27;4:100069
pubmed: 35415678
Cell Physiol Biochem. 2016;39(2):780-9
pubmed: 27467279
Cell Commun Signal. 2011 May 08;9:11
pubmed: 21549004
Nutr Metab Cardiovasc Dis. 2007 Sep;17(7):535-45
pubmed: 16928436
Biochem Biophys Res Commun. 2016 Jan 15;469(3):748-52
pubmed: 26692476
Br J Pharmacol. 2017 Jun;174(11):1209-1225
pubmed: 28071785
Drug Metab Dispos. 2004 Dec;32(12):1377-82
pubmed: 15333514
Apoptosis. 2016 Aug;21(8):905-16
pubmed: 27270300
Curr Mol Med. 2016;16(6):533-44
pubmed: 27211800
Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1246-52
pubmed: 17548692
Biofactors. 2018 Jan;44(1):5-15
pubmed: 29322567
Mini Rev Med Chem. 2011 Dec;11(14):1191-9
pubmed: 22070680
Ann N Y Acad Sci. 2011 Jan;1215:9-15
pubmed: 21261636
Skin Pharmacol Physiol. 2018;31(6):332-336
pubmed: 30235459
Metallomics. 2020 Feb 26;12(2):290-300
pubmed: 31872196
Phytother Res. 2021 Oct;35(10):5564-5583
pubmed: 34114705
Front Pharmacol. 2020 Aug 07;11:1225
pubmed: 32848804
Biochim Biophys Acta. 2013 Dec;1833(12):3460-3470
pubmed: 23850759
Nat Rev Mol Cell Biol. 2020 Aug;21(8):421-438
pubmed: 32457508
Eur J Pharmacol. 2016 Apr 5;776:26-33
pubmed: 26921129
Nutrients. 2016 May 02;8(5):
pubmed: 27144581
J Agric Food Chem. 2021 Feb 10;69(5):1555-1566
pubmed: 33522796
Biomed Pharmacother. 2018 May;101:805-819
pubmed: 29525677
Nutrition. 2017 Feb;34:82-96
pubmed: 28063518