Assessing cardiac mechanical dyssynchrony in left bundle branch area pacing and right ventricular septal pacing using myocardial perfusion scintigraphy in the acute phase of pacemaker implantation.

computed tomography left bundle branch area pacing mechanical dyssynchrony physiological ventricular activation right ventricular septal pacing

Journal

Journal of cardiovascular electrophysiology
ISSN: 1540-8167
Titre abrégé: J Cardiovasc Electrophysiol
Pays: United States
ID NLM: 9010756

Informations de publication

Date de publication:
08 2022
Historique:
revised: 25 05 2022
received: 15 02 2022
accepted: 05 06 2022
pubmed: 25 6 2022
medline: 24 8 2022
entrez: 24 6 2022
Statut: ppublish

Résumé

Left bundle branch area pacing (LBBAP) has recently been reported to be a new, clinically feasible and safe physiological pacing strategy. The present study aims to investigate the usefulness of LBBAP in reducing mechanical dyssynchrony compared with right ventricular septal pacing (RVSP). A total of 39 LBBAP patients, 42 RVSP patients, and 93 healthy control participants were retrospectively evaluated. We compared phase analysis- (bandwidth, phase standard deviation [PSD], entropy) and regional wall motion analysis parameters. Wall motion analysis parameters included the time to the end-systolic frame (TES) assessed using single-photon emission computed tomography analysis. The maximum differences between segmental TES (MDTES), the standard deviation of TES (SDTES), and the TES difference between the lateral and septal segments (DTES-LS) were obtained. All phase analysis parameters were significantly smaller in the LBBAP group than in the RVSP group (bandwidth: LBBAP, 74 ± 31° vs. RVSP, 102 ± 59°, p = .009; PSD: LBBAP, 19 ± 6.7° vs. RVSP, 26 ± 15°, p = .007; entropy: LBBAP, 0.57 ± 0.07 vs. RVSP, 0.62 ± 0.11 p = .009). The regional wall motion analysis parameters were also smaller in the LBBAP group than in the RVSP group (MDTES:LBBAP, 17 ± 7.1% vs. RVSP, 25 ± 14%, p = .004; SDTES:LBBAP, 4.5 ± 1.7% vs. RVSP, 6.0 ± 3.5%, p = .015; DTES-LS: LBBAP, 4.1 ± 3.4% vs. RVSP, 7.1 ± 5.4%, p = .004). All phase analysis and wall motion analysis parameters were same in the LBBAP and control groups. LBBAP may reduce mechanical dyssynchrony and achieve greater physiological ventricular activation than RVSP.

Identifiants

pubmed: 35748386
doi: 10.1111/jce.15609
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1826-1836

Informations de copyright

© 2022 Wiley Periodicals LLC.

Références

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Auteurs

Keisuke Miyajima (K)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Tsuyoshi Urushida (T)

Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

Takumi Tamura (T)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Sakito Masuda (S)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Ayako Okazaki (A)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Yasuyo Takashima (Y)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Tomoyuki Watanabe (T)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Yoshitaka Kawaguchi (Y)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Yasushi Wakabayashi (Y)

Department of Cardiology, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan.

Yuichiro Maekawa (Y)

Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

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