[Current management status of hereditary colorectal cancer].


Journal

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
ISSN: 1671-0274
Titre abrégé: Zhonghua Wei Chang Wai Ke Za Zhi
Pays: China
ID NLM: 101177990

Informations de publication

Date de publication:
25 Jun 2022
Historique:
entrez: 27 6 2022
pubmed: 28 6 2022
medline: 29 6 2022
Statut: ppublish

Résumé

Hereditary colorectal cancer accounts for approximately 5% of all colorectal cancer cases, mainly including familial adenomatous polyposis and Lynch syndrome. Total proctocolectomy plus ileal pouch-anal anastomosis and total colectomy plus ileorectal anastomosis are two major procedures for familial adenomatous polyposis, however, the exact impact of these two procedures on surgical efficacy, oncologic efficacy as well as functional results still remains uncertain. Segmental colectomy and total colectomy are two major procedures for Lynch syndrome, each of them both has advantages and disadvantages, and there still lacks a consensus about the optimal strategy because of the nature of retrospective study with a relatively insufficient evidence support. As a result, we would make a review about the current surgical treatment status and future perspectives of hereditary colorectal cancer. 遗传性结直肠癌约占所有结直肠癌的5%,主要包括家族性腺瘤性息肉病和林奇综合征这两类。全结直肠切除加回肠储袋肛管吻合术和全结肠切除加回肠直肠吻合术是家族性腺瘤性息肉病的主要术式,但两种术式的肿瘤学疗效以及对肛门功能和生活质量的影响仍不明确,结论各异。部分结肠切除术和全结肠或次全结肠切除术是林奇综合征的主要术式,不同术式各有优劣,研究同质化较低,以回顾性研究为主,缺乏充分证据支持。本文将对遗传性结直肠癌手术治疗现状及进展作一总结。.

Autres résumés

Type: Publisher (chi)
遗传性结直肠癌约占所有结直肠癌的5%,主要包括家族性腺瘤性息肉病和林奇综合征这两类。全结直肠切除加回肠储袋肛管吻合术和全结肠切除加回肠直肠吻合术是家族性腺瘤性息肉病的主要术式,但两种术式的肿瘤学疗效以及对肛门功能和生活质量的影响仍不明确,结论各异。部分结肠切除术和全结肠或次全结肠切除术是林奇综合征的主要术式,不同术式各有优劣,研究同质化较低,以回顾性研究为主,缺乏充分证据支持。本文将对遗传性结直肠癌手术治疗现状及进展作一总结。.

Identifiants

pubmed: 35754221
doi: 10.3760/cma.j.cn441530-20211111-00457
doi:

Types de publication

Journal Article

Langues

chi

Sous-ensembles de citation

IM

Pagination

546-551

Auteurs

G B Li (GB)

Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.

Z J Wang (ZJ)

Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.

J G Han (JG)

Department of General Surgery, Beijing Chaoyang Hosptial, Capital Medical University, Beijing 100020, China.

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Classifications MeSH