Long-Term Follow-up of Individual Therapist Delivered and Standardized Hypnotherapy Recordings in Pediatric Irritable Bowel Syndrome or Functional Abdominal Pain.
Journal
Journal of pediatric gastroenterology and nutrition
ISSN: 1536-4801
Titre abrégé: J Pediatr Gastroenterol Nutr
Pays: United States
ID NLM: 8211545
Informations de publication
Date de publication:
01 07 2022
01 07 2022
Historique:
entrez:
27
6
2022
pubmed:
28
6
2022
medline:
30
6
2022
Statut:
ppublish
Résumé
We previously showed that standardized home-based gut-directed hypnosis exercises with compact disc (CD) is non-inferior to individual hypnotherapy (iHT) by a therapist in the treatment of children with irritable bowel syndrome (IBS) and functional abdominal pain (syndrome) (FAP(S)). Aim of this follow-up study was to investigate the long-term effects of standardized-hypnosis-recordings at home in comparison to iHT. All participants from our previous randomized controlled trial were invited to complete: 1) an online standardized abdominal pain dairy, on which pain frequency and intensity were scored, and 2) an online questionnaire including adequate relief (AR), anxiety/depression scores, somatization, quality of life (QOL), pain beliefs, school and/or work absenteeism and health care utilization. 227 out of 250 (91%) participants completed this study. After a median duration of 6 years follow-up (5.8-6.2), 80.0% in the CD group vs 86.6% in the iHT group reported AR of their abdominal complaints (P=.22). Compared to the 1-year follow-up, AR percentages were stable. Treatment success was seen in 67.6% in the CD group vs 71.3% in the iHT group (P=.66). Anxiety and depression scores, somatization, pain beliefs, health care utilization and school/work absenteeism also improved significantly in both study groups compared with baseline. No differences were found in QOL-scores. Both home-based treatment with standardized-hypnosis-recordings and iHT given by a therapist show persisting positive results in more than 80% of children with IBS and FAP(S) after 6 years of follow-up. These results support the rationale for implementation of this easy-to-use, widely available and cost-effective home-treatment in daily practice.
Identifiants
pubmed: 35759537
doi: 10.1097/MPG.0000000000003478
pii: 00005176-202207000-00005
pmc: PMC9236305
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
24-29Informations de copyright
Copyright © 2022 The Author(s). Published by Wolters Kluwer on behalf of European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
Références
Korterink JJ, Diederen K, Benninga MA, et al. Epidemiology of pediatric functional abdominal pain disorders: a meta-analysis. PLoS One. 2015;10:e0126982.
Hyams JS, Di Lorenzo C, Saps M, et al. Functional disorders: children and adolescents. Gastroenterology. 2016;150:1456–1468.e2.
Youssef NN, Murphy TG, Langseder AL, et al. Quality of life for children with functional abdominal pain: a comparison study of patients’ and parents’ perceptions. Pediatrics. 2006;117:54–9.
Varni JW, Bendo CB, Nurko S, et al. Health-related quality of life in pediatric patients with functional and organic gastrointestinal diseases. J Pediatr. 2015;166:85–90.e2.
Assa A, Ish-Tov A, Rinawi F, et al. School attendance in children with functional abdominal pain and inflammatory bowel diseases. J Pediatr Gastroenterol Nutr. 2015;61:553–7.
Youssef NN, Atienza K, Langseder AL, et al. Chronic abdominal pain and depressive symptoms: analysis of the National Longitudinal Study of Adolescent Health. Clin Gastroenterol Hepatol. 2008;6:329–32.
Shelby GD, Shirkey KC, Sherman AL, et al. Functional abdominal pain in childhood and long-term vulnerability to anxiety disorders. Pediatrics. 2013;132:475–82.
Santucci NR, Saps M, van Tilburg MA.New advances in the treatment of paediatric functional abdominal pain disorders. Lancet Gastroenterol Hepatol. 2020;5:316–28.
Gonsalkorale WM. Gut-directed hypnotherapy: the Manchester approach for treatment of irritable bowel syndrome. Int J Clin Exp Hypn. 2006;54:27–50.
Rutten JMTM, Vlieger AM, Frankenhuis C, et al. Gut-directed hypnotherapy in children with irritable bowel syndrome or functional abdominal pain (syndrome): a randomized controlled trial on self exercises at home using CD versus individual therapy by qualified therapists. BMC Pediatr. 2014;14:140.
Vlieger AM, Menko-Frankenhuis C, Wolfkamp SCS, et al. Hypnotherapy for children with functional abdominal pain or irritable bowel syndrome: a randomized controlled trial. Gastroenterology. 2007;133:1430–6.
Rexwinkel R, de Bruijn CMA, Gordon M, Benninga MA, Tabbers MM. Pharmacologic treatment in functional abdominal pain disorders in children: a systematic review. Pediatrics. 2021;147:e2020042101.
Gordon M, Sinopoulou V, Tabbers M, et al. Psychosocial interventions for the treatment of functional abdominal pain disorders in children: a systematic review and meta-analysis. JAMA Pediatr. 2022:e220313. doi: 10.1001/jamapediatrics.2022.0313. Epub ahead of print.
doi: 10.1001/jamapediatrics.2022.0313.
Weerts ZZRM, Heinen KGE, Masclee AAM, et al. Correction: Smart Data Collection for the Assessment of Treatment Effects in Irritable Bowel Syndrome: Observational Study. JMIR Mhealth Uhealth. 2021;9:e27998. doi: 10.2196/27998. Erratum for: JMIR Mhealth Uhealth 2022;8:e19696. PMID: 33600349; PMCID: PMC7932838.
doi: 10.2196/27998.
Gulewitsch MD, Müller J, Hautzinger M, et al. Brief hypnotherapeutic-behavioral intervention for functional abdominal pain and irritable bowel syndrome in childhood: A randomized controlled trial. Eur J Pediatr. 2013;172:1043–51.
Vlieger AM, Rutten JMTM, Govers AMAP, et al. Long-term follow-up of gut-directed hypnotherapy vs. standard care in children with functional abdominal pain or irritable bowel syndrome. Am J Gastroenterol. 2012;107:627–31.
Rutten JMTM, Vlieger AM, Frankenhuis C, et al. Home-based hypnotherapy self-exercises vs individual hypnotherapy with a therapist for treatment of pediatric irritable bowel syndrome, functional abdominal pain, or functional abdominal pain syndrome a randomized clinical trial. JAMA Pediatr. 2017;171:470–7.
Shahbazi K, Solati K, Hasanpour-Dehkordi A. Comparison of hypnotherapy and standard medical treatment alone on quality of life in patients with irritable bowel syndrome: a randomized control trial. J Clin Diagn Res. 2016;10:OC01–4.
van Tilburg MAL, Chitkara DK, Palsson OS, et al. Audio-recorded guided imagery treatment reduces functional abdominal pain in children: a pilot study. Pediatrics. 2009;124:e890–7.
Palsson OS, Turner MJ, Johnson DA, et al. Hypnosis treatment for severe irritable bowel syndrome: investigation of mechanism and effects on symptoms. Dig Dis Sci. 2002;47:2605–14.
Lindfors P, Unge P, Nyhlin H, et al. Long-term effects of hypnotherapy in patients with refractory irritable bowel syndrome. Scand J Gastroenterol. 2012;47:414–21.
Lindfors P, Unge P, Arvidsson P, et al. Effects of gut-directed hypnotherapy on IBS in different clinical settings-results from two randomized, controlled trials. Am J Gastroenterol. 2012;107:276–85.
Saps M, van Tilburg MAL, Lavigne JV, et al. Recommendations for pharmacological clinical trials in children with irritable bowel syndrome: the Rome foundation pediatric subcommittee on clinical trials. Neurogastroenterol Motil. 2016;28:1619–31.
Camilleri M, Mangel AW, Fehnel SE, et al. Primary endpoints for irritable bowel syndrome trials: a review of performance of endpoints. Clin Gastroenterol Hepatol. 2007;5:534–40.
Creed F, Sci FM, Ratcliffe J, et al. Health-related quality of life and health care costs in severe, refractory irritable bowel syndrome. Ann Intern Med. 2001;134(9 Part 2):860–8.
Mangel A, Hahn B, Heath A, et al. Adequate relief as an endpoint in clinical trials in irritable bowel syndrome. J Int Med Res. 1998;26:76–81.
See MC, Birnbaum AH, Schechter CB, et al. Double-blind, placebo-controlled trial of famotidine in children with abdominal pain and dyspepsia: Global and quantitative assessment. Dig Dis Sci. 2001;46:985–92.
Whorwell P, Prior A, Faragher E.Controlled trial of hypnotherapy in the treatment of severe refractory irritable-bowel syndrome. Lancet. 1984;324:1232–4.
RStudio Team. RStudio: Integrated Development for R. Boston, MA: RStudio, PBC2020.
Rutten JMTM, van Barreveld A, Vlieger A, et al. Cost-effectiveness and cost-utility of home-based hypnotherapy using CD versus individual hypnotherapy by a therapist in pediatric irritable bowel syndrome and functional abdominal pain (syndrome). Unpublished. 2015.
Heinsch ML, Nightingale S. Functional gastrointestinal disorders in children and adolescents: knowledge, practice and attitudes of Australian paediatricians. J Paediatr Child Health. 2019;55:1063–9.
Hypnosebijbuikpijn. Available at https://hypnosebijbuikpijn.nl . Accessed January 5, 2021.
hypnosis4abdominalpain. Available at https://hypnosis4abdominalpain.com . Accessed January 5, 2021.
Hipnosis dolor abdominal. Available at http://hipnosisdolorabdominal.com . Accessed January 5, 2021.
Rexwinkel R, de Bruijn CMA, Gordon M, et al. Pharmacologic treatment in functional abdominal pain disorders in children: a systematic review. Pediatrics. 2021;147.
Gordon M, Sinopoulou V, Tabbers MM, et al. Psychosocial interventions for the treatment of Functional Abdominal Pain Disorders in Children: A systematic review and meta-analysis. Paper presented at: BSPGHAN Scientific Meeting January 2022; Brimingham, UK.
Thapar N, Benninga MA, Crowell MD, et al. Paediatric functional abdominal pain disorders. Nat Rev Dis Prim. 2020;6:89.
Lindley KJ, Glaser D, Milla PJ. Consumerism in healthcare can be detrimental to child health: lessons from children with functional abdominal pain. Arch Dis Child. 2005;90:335–7.
Michel G, Bisegger C, Fuhr DC, et al. Age and gender differences in health-related quality of life of children and adolescents in Europe: A multilevel analysis. Qual Life Res. 2009;18:1147–57.
Ravens-Sieberer U, Gosch A, Rajmil L, et al. The KIDSCREEN-52 quality of life measure for children and adolescents: psychometric results from a cross-cultural survey in 13 European countries. Value Heal. 2008;11:645–58.
Cui W, Zack MM. Trends in health-related quality of life among adolescents in the United States, 2001–2010. Prev Chronic Dis. 2013;10:2007–8.
Weerts ZZRM, Vork L, Mujagic Z, et al. Reduction in IBS symptom severity is not paralleled by improvement in quality of life in patients with irritable bowel syndrome. Neurogastroenterol Motil. 2019;31:1–10.
Kongsved SM, Basnov M, Holm-Christensen K, et al. Response rate and completeness of questionnaires: A randomized study of internet versus paper-and-pencil versions. J Med Internet Res. 2007;9:1–11.
Weerts ZZRM, Heinen KGE, Masclee AAM, et al. Smart data collection for the assessment of treatment effects in irritable bowel syndrome: observational study. JMIR mHealth uHealth. 2020;8.
Stone AA, Shiffman S, Schwartz JE, et al. Patient compliance with paper and electronic diaries. Control Clin Trials. 2003;24:182–99.
Burton C, Weller D, Sharpe M. Are electronic diaries useful for symptoms research? A systematic review. J Psychosom Res. 2007;62:553–61.
Morren M, van Dulmen S, Ouwerkerk J, et al. Compliance with momentary pain measurement using electronic diaries: a systematic review. Eur J Pain. 2009;13:354–65.
Walker LS, Guite JW, Duke M, et al. Recurrent abdominal pain: a potential precursor of irritable bowel syndrome in adolescents and young adults. J Pediatr. 1998;132:1010–5.
Gieteling MJ, Bierma-Zeinstra SMA, Passchier J, et al. Prognosis of chronic or recurrent abdominal pain in children. J Pediatr Gastroenterol Nutr. 2008;47:316–26.
Bhandari A, Wagner T. Self-reported utilization of health care services: improving measurement and accuracy. Med Care Res Rev. 2006;63:217–35.