A long noncoding RNA influences the choice of the X chromosome to be inactivated.
X chromosome inactivation
X-controlling element
female mouse embryo
noncoding RNA
pluripotency factors
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
12 07 2022
12 07 2022
Historique:
entrez:
5
7
2022
pubmed:
6
7
2022
medline:
7
7
2022
Statut:
ppublish
Résumé
X chromosome inactivation (XCI) is the process of silencing one of the X chromosomes in cells of the female mammal which ensures dosage compensation between the sexes. Although theoretically random in somatic tissues, the choice of which X chromosome is chosen to be inactivated can be biased in mice by genetic element(s) associated with the so-called X-controlling element (
Identifiants
pubmed: 35787055
doi: 10.1073/pnas.2118182119
pmc: PMC9282422
doi:
Substances chimiques
RNA, Long Noncoding
0
XIST non-coding RNA
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2118182119Commentaires et corrections
Type : CommentIn
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