Imaging approaches and radiomics: toward a new era of ultraprecision radioimmunotherapy?
immunotherapy
radioimmunotherapy
radiotherapy
tumor biomarkers
Journal
Journal for immunotherapy of cancer
ISSN: 2051-1426
Titre abrégé: J Immunother Cancer
Pays: England
ID NLM: 101620585
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
accepted:
21
06
2022
entrez:
6
7
2022
pubmed:
7
7
2022
medline:
9
7
2022
Statut:
ppublish
Résumé
Strong rationale and a growing number of preclinical and clinical studies support combining radiotherapy and immunotherapy to improve patient outcomes. However, several critical questions remain, such as the identification of patients who will benefit from immunotherapy and the identification of the best modalities of treatment to optimize patient response. Imaging biomarkers and radiomics have recently emerged as promising tools for the non-invasive assessment of the whole disease of the patient, allowing comprehensive analysis of the tumor microenvironment, the spatial heterogeneity of the disease and its temporal changes. This review presents the potential applications of medical imaging and the challenges to address, in order to help clinicians choose the optimal modalities of both radiotherapy and immunotherapy, to predict patient's outcomes and to assess response to these promising combinations.
Identifiants
pubmed: 35793875
pii: jitc-2022-004848
doi: 10.1136/jitc-2022-004848
pmc: PMC9260846
pii:
doi:
Substances chimiques
Immunologic Factors
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: ED has declared consulting fees and support from Roche, BMS, Boehringer, Astrazeneca, Lilly Amgen, and Merck-Serono. The remaining authors have no conflicts of interest to declare that are relevant to the content of this article.
Références
Front Oncol. 2021 Apr 23;11:591106
pubmed: 33968716
BJR Open. 2019 Nov 28;2(1):20190031
pubmed: 33178962
Lancet Oncol. 2009 Jul;10(7):718-26
pubmed: 19573801
Eur J Cancer. 2009 Jan;45(2):228-47
pubmed: 19097774
J Immunother Cancer. 2021 Apr;9(4):
pubmed: 33849924
Cancer Radiother. 2017 Oct;21(6-7):648-654
pubmed: 28865968
Cancer Res. 2016 Jan 1;76(1):73-82
pubmed: 26573799
Cancer Cell. 2018 Dec 10;34(6):1012-1026.e3
pubmed: 30537506
Neuro Oncol. 2015 Sep;17(9):1188-98
pubmed: 26250565
J Clin Oncol. 2018 Mar 20;36(9):850-858
pubmed: 29341833
Cancer Discov. 2022 Jan;12(1):108-133
pubmed: 34479871
Eur Radiol. 2021 Aug;31(8):6001-6012
pubmed: 33492473
Lancet Oncol. 2022 Mar;23(3):e105-e115
pubmed: 35240087
Cancer Treat Rev. 2015 Jun;41(6):503-10
pubmed: 25872878
Med Phys. 2022 Mar;49(3):1547-1558
pubmed: 35026041
Nat Rev Clin Oncol. 2017 Jun;14(6):365-379
pubmed: 28094262
Br J Radiol. 1953 May;26(305):234-41
pubmed: 13042090
Cancer Immunol Res. 2016 Sep 2;4(9):744-54
pubmed: 27466265
Med Res Rev. 2022 Jan;42(1):441-461
pubmed: 34346083
Sci Adv. 2020 Jul 10;6(28):eaba6156
pubmed: 32832602
Theranostics. 2016 Jun 18;6(10):1629-40
pubmed: 27446497
Radiol Oncol. 2020 Jul 29;54(3):285-294
pubmed: 32726293
J Immunother Cancer. 2021 Feb;9(2):
pubmed: 33593828
Eur Radiol. 2020 Oct;30(10):5392-5403
pubmed: 32394281
JNCI Cancer Spectr. 2021 May 13;5(4):
pubmed: 34409252
Cancers (Basel). 2020 May 05;12(5):
pubmed: 32380754
Radiology. 2019 Apr;291(1):53-59
pubmed: 30694160
Lancet Oncol. 2019 Aug;20(8):e417-e433
pubmed: 31364594
N Engl J Med. 2012 Mar 8;366(10):883-892
pubmed: 22397650
J Clin Oncol. 2021 Jan 1;39(1):30-37
pubmed: 32822275
Sci Immunol. 2021 Apr 9;6(58):
pubmed: 33837124
Bioconjug Chem. 2018 Jan 17;29(1):96-103
pubmed: 29125731
Thorac Cancer. 2020 Apr;11(4):993-1004
pubmed: 32043309
Clin Genitourin Cancer. 2021 Oct;19(5):396-404
pubmed: 33849811
Cancer Res. 2012 Jul 1;72(13):3163-74
pubmed: 22570253
Int J Radiat Oncol Biol Phys. 2019 Dec 1;105(5):1065-1073
pubmed: 31476418
Neuroimage. 2017 Nov 1;161:149-170
pubmed: 28826946
Int J Radiat Oncol Biol Phys. 2020 Sep 1;108(1):189-195
pubmed: 32569799
Radiology. 2020 May;295(2):328-338
pubmed: 32154773
Cancers (Basel). 2022 Jan 11;14(2):
pubmed: 35053513
Radiology. 2020 Mar;294(3):487-489
pubmed: 31891322
J Immunother Cancer. 2021 Jun;9(6):
pubmed: 34135101
J Clin Oncol. 2020 Aug 10;38(23):2667-2676
pubmed: 32552274
Diagnostics (Basel). 2021 May 28;11(6):
pubmed: 34071518
Int J Clin Oncol. 2020 May;25(5):801-809
pubmed: 32246277
J Immunother Cancer. 2020 Oct;8(2):
pubmed: 33051340
Eur Radiol. 2020 Jul;30(7):3759-3769
pubmed: 32086577
Lancet Oncol. 2018 Sep;19(9):1180-1191
pubmed: 30120041
Methods. 2021 Apr;188:44-60
pubmed: 32697964
Neuro Oncol. 2020 Aug 17;22(8):1214-1225
pubmed: 32152626
Lancet Oncol. 2021 Apr;22(4):450-462
pubmed: 33794205
Phys Med Biol. 2016 Jul 7;61(13):R150-66
pubmed: 27269645
Elife. 2017 Jul 21;6:
pubmed: 28731408
J Immunother Cancer. 2020 Jul;8(2):
pubmed: 32636239
World J Urol. 2021 Sep;39(9):3707-3709
pubmed: 32632555
IEEE Rev Biomed Eng. 2017;10:213-234
pubmed: 28092576
JAMA Oncol. 2022 Mar 01;8(3):385-392
pubmed: 35050320
Eur J Nucl Med Mol Imaging. 2020 May;47(5):1302-1313
pubmed: 31883023
Lung Cancer. 2019 Mar;129:75-79
pubmed: 30797495
J Natl Cancer Inst. 2013 Feb 20;105(4):256-65
pubmed: 23291374
Nat Commun. 2017 Jun 09;8:15618
pubmed: 28598415
Oncoimmunology. 2020 Sep 29;9(1):1824316
pubmed: 33457100
Mol Oncol. 2020 Jul;14(7):1529-1537
pubmed: 32112478
Front Oncol. 2021 Mar 02;11:609054
pubmed: 33738253
Bioconjug Chem. 2015 Oct 21;26(10):2062-9
pubmed: 26307602
Front Oncol. 2021 Feb 24;11:544339
pubmed: 33718125
Clin Cancer Res. 2015 Aug 15;21(16):3727-39
pubmed: 25869387
Eur J Cancer. 2016 Jul;62:132-7
pubmed: 27189322
J Clin Oncol. 2016 May 1;34(13):1510-7
pubmed: 26951310
Cancer Radiother. 2017 May;21(3):244-255
pubmed: 28522277
Clin Cancer Res. 2009 Sep 1;15(17):5379-88
pubmed: 19706802
Ann Oncol. 2019 Mar 1;30(3):385-396
pubmed: 30657859
Sci Rep. 2020 Jul 23;10(1):12340
pubmed: 32704007
Clin Radiol. 2010 Jul;65(7):517-21
pubmed: 20541651
N Engl J Med. 2018 Dec 13;379(24):2342-2350
pubmed: 30280658
Acad Radiol. 2020 Feb;27(2):171-179
pubmed: 31147234
Mol Cancer Res. 2021 Jun;19(6):950-956
pubmed: 33811161
Cancer Res. 2017 Nov 1;77(21):e104-e107
pubmed: 29092951
Immunity. 2018 Apr 17;48(4):812-830.e14
pubmed: 29628290
Lancet Oncol. 2015 Jul;16(7):795-803
pubmed: 26095785
Sci Rep. 2021 Mar 23;11(1):6633
pubmed: 33758304
J Clin Oncol. 2018 Jun 1;36(16):1611-1618
pubmed: 29437535
Int J Radiat Oncol Biol Phys. 2016 Aug 1;95(5):1544-1545
pubmed: 27479727
Clin Cancer Res. 2009 Dec 1;15(23):7412-20
pubmed: 19934295
J Pathol. 2014 Jan;232(2):199-209
pubmed: 24122236
Clin Cancer Res. 2017 Apr 15;23(8):1920-1928
pubmed: 27827313
Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):862-70
pubmed: 14967443
Oncoimmunology. 2017 May 19;6(7):e1329071
pubmed: 28811971
Abdom Radiol (NY). 2019 Nov;44(11):3755-3763
pubmed: 31250180
Lancet Oncol. 2017 Mar;18(3):e143-e152
pubmed: 28271869
Lancet Respir Med. 2021 May;9(5):467-475
pubmed: 33096027
Radiother Oncol. 2019 Jan;130:2-9
pubmed: 30416044
Clin Cancer Res. 2021 Oct 1;27(19):5325-5333
pubmed: 34253583
Sci Rep. 2021 May 7;11(1):9758
pubmed: 33963236
Lancet Oncol. 2019 Aug;20(8):e452-e463
pubmed: 31364597
Nature. 2015 Apr 16;520(7547):373-7
pubmed: 25754329
Am J Transl Res. 2021 Feb 15;13(2):743-756
pubmed: 33594323
Lancet Oncol. 2014 Jun;15(7):700-12
pubmed: 24831977
Strahlenther Onkol. 2018 Jun;194(6):509-519
pubmed: 29500551
Bioconjug Chem. 2019 May 15;30(5):1434-1441
pubmed: 30973703
Cancers (Basel). 2021 Aug 07;13(16):
pubmed: 34439148
Nat Med. 2018 Dec;24(12):1852-1858
pubmed: 30478423
Oncotarget. 2016 Feb 16;7(7):7913-24
pubmed: 26761210
Ann Oncol. 2019 Jun 1;30(6):998-1004
pubmed: 30895304
Cancer Manag Res. 2020 Sep 30;12:9389-9403
pubmed: 33061627
Blood. 2009 Jul 16;114(3):589-95
pubmed: 19349616
Eur J Nucl Med Mol Imaging. 2020 May;47(5):1168-1182
pubmed: 31807885
J Immunother Cancer. 2020 Nov;8(2):
pubmed: 33188037
Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6506-14
pubmed: 26604307
Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1117-1142
pubmed: 30064704
Nat Commun. 2017 Nov 24;8(1):1751
pubmed: 29170499
Cancer Immunol Immunother. 2021 Jun;70(6):1667-1678
pubmed: 33315149
Clin Cancer Res. 2003 Oct 1;9(12):4318-23
pubmed: 14555501
PLoS One. 2021 Aug 24;16(8):e0255923
pubmed: 34428218
Lancet Oncol. 2022 Feb;23(2):279-291
pubmed: 35033226
Eur Urol. 2019 May;75(5):707-711
pubmed: 30665814
Ann Oncol. 2017 Jun 1;28(6):1191-1206
pubmed: 28168275
Magn Reson Imaging. 2019 Dec;64:160-170
pubmed: 31301354
Immunol Rev. 2017 Nov;280(1):231-248
pubmed: 29027224
JAMA Oncol. 2019 Sep 01;5(9):1276-1282
pubmed: 31294749
Eur Urol Oncol. 2020 Oct;3(5):680-686
pubmed: 31412003
Lancet Digit Health. 2021 Jun;3(6):e371-e382
pubmed: 34045003
Med Image Anal. 2019 May;54:280-296
pubmed: 30959445
Lung Cancer. 2020 Aug;146:197-208
pubmed: 32563015
Respir Res. 2021 Jun 28;22(1):189
pubmed: 34183009
Comput Biol Med. 2021 Nov;138:104916
pubmed: 34656867
J Immunother Cancer. 2021 Nov;9(11):
pubmed: 34795006
Acad Radiol. 2021 Jun;28(6):e147-e154
pubmed: 32499156
Front Oncol. 2021 Mar 19;11:657615
pubmed: 33816314
J Nucl Med. 2022 May;63(5):720-726
pubmed: 34413145
Front Oncol. 2021 Aug 06;11:620246
pubmed: 34422625
Cancer Immunol Res. 2020 Jan;8(1):108-119
pubmed: 31719058
Front Oncol. 2021 Jul 07;11:697497
pubmed: 34307164
Nat Rev Clin Oncol. 2019 Feb;16(2):123-135
pubmed: 30401936
Eur Radiol. 2019 Aug;29(8):4177-4187
pubmed: 30666445
Eur Radiol. 2020 Oct;30(10):5602-5610
pubmed: 32417949
Nat Rev Clin Oncol. 2017 Dec;14(12):749-762
pubmed: 28975929