Daycare Attendance is Linked to Increased Risk of Respiratory Morbidities in Children Born Preterm with Bronchopulmonary Dysplasia.


Journal

The Journal of pediatrics
ISSN: 1097-6833
Titre abrégé: J Pediatr
Pays: United States
ID NLM: 0375410

Informations de publication

Date de publication:
10 2022
Historique:
received: 04 03 2022
revised: 06 05 2022
accepted: 05 06 2022
pubmed: 9 7 2022
medline: 13 10 2022
entrez: 8 7 2022
Statut: ppublish

Résumé

To test the hypothesis that daycare attendance among children with bronchopulmonary dysplasia (BPD) is associated with increased chronic respiratory symptoms and/or greater health care use for respiratory illnesses during the first 3 years of life. Daycare attendance and clinical outcomes were obtained via standardized instruments for 341 subjects recruited from 9 BPD specialty clinics in the US. All subjects were former infants born preterm (<34 weeks) with BPD (71% severe) requiring outpatient follow-up between 0 and 3 years of age. Mixed logistic regression models were used to test for associations. Children with BPD attending daycare were more likely to have emergency department visits and systemic steroid usage. Children in daycare up to 3 years of age also were more likely to report trouble breathing, having activity limitations, and using rescue medications when compared with children not in daycare. More severe manifestations were found in children attending daycare between 6 and 12 months of chronological age. In this study, children born preterm with BPD who attend daycare were more likely to visit the emergency department, use systemic steroids, and have chronic respiratory symptoms compared with children not in daycare, indicating that daycare may be a potential modifiable risk factor to minimize respiratory morbidities in children with BPD during the preschool years.

Identifiants

pubmed: 35803300
pii: S0022-3476(22)00617-5
doi: 10.1016/j.jpeds.2022.06.037
pmc: PMC10588550
mid: NIHMS1936712
pii:
doi:

Substances chimiques

Steroids 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

22-28.e1

Subventions

Organisme : NHLBI NIH HHS
ID : K23 HL136851
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL114800
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL140572
Pays : United States

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

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Auteurs

Sharon A McGrath-Morrow (SA)

Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA. Electronic address: mcgrathmos@chop.edu.

Amit Agarwal (A)

Division of Pediatric Pulmonary and Sleep Medicine, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR.

Stamatia Alexiou (S)

Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA.

Eric D Austin (ED)

Pulmonary Medicine, Vanderbilt University and Vanderbilt University Medical Center, Nashville, TN.

Julie L Fierro (JL)

Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA.

Lystra P Hayden (LP)

Division of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA.

Khanh Lai (K)

Division of Pediatric Pulmonary and Sleep Medicine, University of Utah, Salt Lake City, UT.

Jonathan C Levin (JC)

Division of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA.

Winston M Manimtim (WM)

Neonatal/Perinatal Medicine, Children's Mercy Hospital, Kansas City, MO.

Paul E Moore (PE)

Pulmonary Medicine, Vanderbilt University and Vanderbilt University Medical Center, Nashville, TN.

Lawrence M Rhein (LM)

Neonatal-Perinatal Medicine/Pediatric Pulmonology, University of Massachusetts, Worcester, MA.

Jessica L Rice (JL)

Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA.

Catherine A Sheils (CA)

Division of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA.

Michael C Tracy (MC)

Division of Pediatric Pulmonary, Stanford University, Stanford, CA.

Manvi Bansal (M)

Pulmonology and Sleep Medicine, Children's Hospital of Los Angeles, Los Angeles, CA.

Christopher D Baker (CD)

Section of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO.

A Ioana Cristea (AI)

Division of Pediatric Pulmonology, Allergy and Sleep Medicine, Riley Children's Hospital and Indiana University, Indianapolis, IN.

Antonia P Popova (AP)

Pediatric Pulmonology, University of Michigan, Ann Arbor, MI.

Roopa Siddaiah (R)

Pediatric Pulmonology, Penn State Health, Hershey, PA.

Natalie Villafranco (N)

Pulmonary Medicine, Texas Children's Hospital and Baylor University, Houston, TX.

Leif D Nelin (LD)

Division of Neonatology, Nationwide Children's Hospital and Ohio State University, Columbus, OH.

Joseph M Collaco (JM)

Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, MD.

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