Renal Artery Aneurysms in the Inpatient Setting.


Journal

Annals of vascular surgery
ISSN: 1615-5947
Titre abrégé: Ann Vasc Surg
Pays: Netherlands
ID NLM: 8703941

Informations de publication

Date de publication:
Oct 2022
Historique:
received: 23 04 2022
revised: 22 05 2022
accepted: 30 05 2022
pubmed: 9 7 2022
medline: 15 11 2022
entrez: 8 7 2022
Statut: ppublish

Résumé

The risk of rupture of renal artery aneurysms (RAAs) remains undefined. A recent paper from the Vascular Low-Frequency Disease Consortium (VLFDC) identified only 3 ruptures in 760 patients. However, over 80% of patients in the VLFDC study were treated at large academic centers, which may not reflect the pattern of care of RAAs nationwide. Thus, the purpose of this study was to evaluate the pattern of nonelective versus elective surgery requiring inpatient admission for RAAs, including nephrectomies, and their outcomes using a national database. The National Inpatient Sample (NIS) database from 2012 to 2018 was utilized. Patients with a primary diagnosis of RAAs were identified using ICD-9 and ICD-10 codes. Ruptured RAAs (rRAAs) were identified utilizing surrogate ICD codes. The primary outcome variables for this study were proportion of RAAs requiring non-elective surgery and in-hospital mortality. A total of 590 inpatient admissions for RAA were identified with 554 procedures at 467 hospitals across the country. Of the 590 inpatient admissions, 380 (64.4%) admissions were deemed nonelective. There was an increasing proportion of nonelective admissions over the study period. The overall rate of nephrectomies was 7.1% (n = 42). In-hospital mortality rate for the cohort was 1.4% (n = 8) with no differences in in-hospital mortality in the elective versus nonelective setting (1.0% vs. 1.6%; P = 0.718). In the nonelective setting, patients requiring a nephrectomy (n = 23) had significantly higher rates of in-hospital mortality compared those not requiring a nephrectomy (8.7% vs. 1.1%, P = 0.045). rRAA (n = 50) patients had significantly higher in-hospital mortality compared to the remainder of the cohort (6.0% vs. 0.9%, P = 0.024). rRAA patients were also more likely to undergo a nephrectomy compared to the remainder of the cohort (16.0% vs. 6.3%, P = 0.019). These data demonstrate that treatment of RAAs are primarily done in the nonelective setting with a high proportion of ruptures, which could continue to rise as the threshold for repair has decreased.

Sections du résumé

BACKGROUND BACKGROUND
The risk of rupture of renal artery aneurysms (RAAs) remains undefined. A recent paper from the Vascular Low-Frequency Disease Consortium (VLFDC) identified only 3 ruptures in 760 patients. However, over 80% of patients in the VLFDC study were treated at large academic centers, which may not reflect the pattern of care of RAAs nationwide. Thus, the purpose of this study was to evaluate the pattern of nonelective versus elective surgery requiring inpatient admission for RAAs, including nephrectomies, and their outcomes using a national database.
METHODS METHODS
The National Inpatient Sample (NIS) database from 2012 to 2018 was utilized. Patients with a primary diagnosis of RAAs were identified using ICD-9 and ICD-10 codes. Ruptured RAAs (rRAAs) were identified utilizing surrogate ICD codes. The primary outcome variables for this study were proportion of RAAs requiring non-elective surgery and in-hospital mortality.
RESULTS RESULTS
A total of 590 inpatient admissions for RAA were identified with 554 procedures at 467 hospitals across the country. Of the 590 inpatient admissions, 380 (64.4%) admissions were deemed nonelective. There was an increasing proportion of nonelective admissions over the study period. The overall rate of nephrectomies was 7.1% (n = 42). In-hospital mortality rate for the cohort was 1.4% (n = 8) with no differences in in-hospital mortality in the elective versus nonelective setting (1.0% vs. 1.6%; P = 0.718). In the nonelective setting, patients requiring a nephrectomy (n = 23) had significantly higher rates of in-hospital mortality compared those not requiring a nephrectomy (8.7% vs. 1.1%, P = 0.045). rRAA (n = 50) patients had significantly higher in-hospital mortality compared to the remainder of the cohort (6.0% vs. 0.9%, P = 0.024). rRAA patients were also more likely to undergo a nephrectomy compared to the remainder of the cohort (16.0% vs. 6.3%, P = 0.019).
CONCLUSIONS CONCLUSIONS
These data demonstrate that treatment of RAAs are primarily done in the nonelective setting with a high proportion of ruptures, which could continue to rise as the threshold for repair has decreased.

Identifiants

pubmed: 35803463
pii: S0890-5096(22)00318-1
doi: 10.1016/j.avsg.2022.05.045
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

50-57

Informations de copyright

Published by Elsevier Inc.

Auteurs

Mitri K Khoury (MK)

University of Texas Southwestern, Dallas, TX; Division of Vascular and Endovascular Surgery, Dallas, TX.

Fred A Weaver (FA)

University of Southern California, Los Angeles, CA; Division of Vascular and Endovascular Surgery, Los Angeles, CA.

Shirling Tsai (S)

University of Texas Southwestern, Dallas, TX; Division of Vascular and Endovascular Surgery, Dallas, TX; Surgical Service, Dallas Veterans Affairs Medical Center, Dallas, TX.

Nicole M Nevarez (NM)

University of Texas Southwestern, Dallas, TX; Division of Vascular and Endovascular Surgery, Dallas, TX.

Bala Ramanan (B)

University of Texas Southwestern, Dallas, TX; Division of Vascular and Endovascular Surgery, Dallas, TX; Surgical Service, Dallas Veterans Affairs Medical Center, Dallas, TX.

Melissa L Kirkwood (ML)

University of Texas Southwestern, Dallas, TX; Division of Vascular and Endovascular Surgery, Dallas, TX.

J Gregory Modrall (JG)

University of Texas Southwestern, Dallas, TX; Division of Vascular and Endovascular Surgery, Dallas, TX; Surgical Service, Dallas Veterans Affairs Medical Center, Dallas, TX. Electronic address: greg.modrall@utsouthwestern.edu.

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