Harmonics and frequency-modulated calls indicate different motivational states in rats.
Affective state
Approach behavior
Rhythmic stroking
Tactile reward
Ultrasonic vocalization
Journal
Behavioural processes
ISSN: 1872-8308
Titre abrégé: Behav Processes
Pays: Netherlands
ID NLM: 7703854
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
09
03
2022
revised:
16
05
2022
accepted:
29
06
2022
pubmed:
9
7
2022
medline:
10
8
2022
entrez:
8
7
2022
Statut:
ppublish
Résumé
Rats emit 50-kHz ultrasonic vocalizations (USVs) via the accumbal dopaminergic system in response to rhythmic stroking (RS). However, it is unknown whether RS can lead to approach behavior, which is a reliable marker of positive affective states. To assess the effects of RS on the behavioral response and its correlation with call subtypes, we measured the total number of 50-kHz USVs (overall and within call subtypes) and approach behavior in response to RS. Rats were randomly divided into two equal groups. One group received RS and the control group received light touch (LT). RS stimulation was administered for 30 s once a day for 7 consecutive days, and USVs were recorded immediately before, during, and after stimulation. RS induced 50-kHz USVs from day 1 and led to quick approach on day 2 and after. However, those responses were absent in the LT group. Specific frequency-modulated (FM) calls observed after RS were significantly correlated with approach latency. These results suggest that RS has rewarding effects, and the specific FM calls observed immediately after RS can be used as indices of innate positive reinforcement.
Identifiants
pubmed: 35803487
pii: S0376-6357(22)00114-0
doi: 10.1016/j.beproc.2022.104697
pii:
doi:
Substances chimiques
Dopamine
VTD58H1Z2X
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104697Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.