Cystic fibrosis related diabetes is not associated with maximal aerobic exercise capacity in cystic fibrosis: a cross-sectional analysis of an international multicenter trial.

Humans Female Male Cystic Fibrosis / complications Cross-Sectional Studies Diabetes Mellitus Exercise Test Exercise

Cystic fibrosis related diabetes Dysglycaemia Exercise capacity Peak oxygen uptake Physical activity

Journal

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

ISSN: 1873-5010

Titre abrégé: J Cyst Fibros

Pays: Netherlands

ID NLM: 101128966

Informations de publication

Date de publication:
01 2023

Historique:

received: 15 04 2022

revised: 24 06 2022

accepted: 27 06 2022

pubmed: 9 7 2022

medline: 15 3 2023

entrez: 8 7 2022

Statut: ppublish

Résumé

Previous studies have reported differences in aerobic exercise capacity, expressed as peak oxygen uptake (VO Baseline data from the international multicenter trial ACTIVATE-CF with participants ≥12 years performing up to 4 h per week of vigorous physical activity were used for this project. Multivariable models were computed to study associations between CFRD and VO Among 117 randomized individuals, 103 (52% female) had a maximal exercise test and were included in the analysis. Participants with (n = 19) and without (n = 84) CFRD did not differ in FEV This study suggests no meaningful differences in VO

Sections du résumé

BACKGROUND

Previous studies have reported differences in aerobic exercise capacity, expressed as peak oxygen uptake (VO

METHODS

Baseline data from the international multicenter trial ACTIVATE-CF with participants ≥12 years performing up to 4 h per week of vigorous physical activity were used for this project. Multivariable models were computed to study associations between CFRD and VO

RESULTS

Among 117 randomized individuals, 103 (52% female) had a maximal exercise test and were included in the analysis. Participants with (n = 19) and without (n = 84) CFRD did not differ in FEV

CONCLUSIONS

This study suggests no meaningful differences in VO

Identifiants

DOI: 10.1016/j.jcf.2022.06.012 PMID: 35803884

pubmed: 35803884

pii: S1569-1993(22)00599-9

doi: 10.1016/j.jcf.2022.06.012

pii:

doi:

Types de publication

Multicenter Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

31-38

Investigateurs

Ernst Eber (E)

Marlies Wagner (M)

Helmut Ellemunter (H)

Larry C Lands (LC)

Nancy Alarie (N)

Chantal Karila (C)

Clotilde Simon (C)

Anne Faucou (A)

Laurent Mely (L)

Bruno Ravaninjatovo (B)

Anne Prevotat (A)

Helge Hebestreit (H)

Jonathan Schaeff (J)

Lothar Stein (L)

Cordula Koerner-Rettberg (C)

Jutta Hammermann (J)

Christina Smaczny (C)

Inka Held (I)

Sibylle Junge (S)

Oliver Nitsche (O)

Rainald Fischer (R)

Jörg Große-Onnebrink (J)

Anne Wesner (A)

Andreas Hector (A)

Alexandra Hebestreit (A)

Susi Kriemler (S)

Christian Schindler (C)

Thomas Radtke (T)

Christian Benden (C)

Carmen Casaulta (C)

Reta Fischer (R)

Alexander Möller (A)

Erik Hulzebos (E)

Marcella Burghard (M)

Don S Urquhart (DS)

Sarah Blacklock (S)

Debbie Miller (D)

Zoe Johnstone (Z)

David M Orenstein (DM)

John D Lowman (JD)

Informations de copyright

Déclaration de conflit d'intérêts

Conflict of interest None.